| Abstract: | Changes in the activities of two enzymes, viz., glutamic oxalacetic transaminase (GOT) and glutamic pyruvic transaminase (GPT) following exposure to the pyrethroids fenvalerate and decis (deltamethrin), the carbamate sevin (carbaryl), singly, and the binary mixtures of fenvalerate + sevin and decis + sevin was studied in the nervous tissue of the fresh water snail Lymnaea acuminata. The total amount of the pesticides administered in the binary mixtures was very low as compared to the amount contained in the 40% LC50 and 80% LC50 of any of the pesticides when given alone. On the one hand, lower quantities of pesticides were administered, while on the other, there was greater enhancement in the activities of the two transaminases. Thus, synergism in case of transaminase activity was much more as compared to synergism when lethality was taken as a criterion. The order of effectiveness of the pesticides/mixtures was decis + sevin > fenvalerate + sevin > decis > fenvalerate > sevin. |
