| Study on the excretive ratio of Toluene Diisocyanate in mice feces |
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| 作者姓名： | Yubin JI Chenfeng JI Xiang ZOU Huixin LIU |
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| 作者单位： | [1]Research Center on Life Science and Environmental Science of Harbin University of Commerce, Harbin 150002, China [2]Postdoctal Research of the Institute of Material Medical of Harbin University of Commerce, Harbin 150002, China |
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| 摘 要： | To detect the excretion ratio of Toluene Diisocyanate （TDI） in mice feces by HPLC. The chromatogram column is C18-ODS, the mobile phase is Acetonitrile -H2O （45 ： 55）, the flow rate is 1mL/min. The detection wavelength is 254 nm, and the quantity is determined by outer mark method. The linear relationship of concentrations of TDI was shown well in the range of 1.2 mol/L-5.2 mol/L, and the recovery ratio was 96.48%, precision degree within the day was under 2.9% and in the day it was under 3.37%. This method was simple, convenient and viable. And the result showed that the excretive ratio of TDI in mice feces was distinctly increased with the dosage given by p.o, which proved that feces were the chief mode of archetypal excretion of TDI given by p.o.
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| 关 键 词： | TDI 二异氰酸盐 排泄物 环境激素 HPLC |
Study on the excretive ratio of Toluene Diisocyanate in mice feces |
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| Yubin JI Chenfeng JI Xiang ZOU Huixin LIU.Study on the excretive ratio of Toluene Diisocyanate in mice feces[J].Chinese Journal of Geochemistry,2006,25(B08):186-186. |
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| Abstract: | |
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| Keywords: | Toluene Diisocyanate excretion environmental hormone HPLC |
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