| 鱼类生长激素的分子生物学和应用研究的进展 |
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| 引用本文： | 徐斌,李德尚,张培军.鱼类生长激素的分子生物学和应用研究的进展[J].海洋与湖沼,1997,28(5):553-557. |
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| 作者姓名： | 徐斌 李德尚 张培军 |
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| 作者单位： | 青岛海洋大学国家教委水产养殖开放研究实验室!青岛，266003，青岛海洋大学国家教委水产养殖开放研究实验室!青岛，266003，中国科学院海洋研究所!青岛，266071 |
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| 基金项目： | 国家自然科学基金!39470553 |
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| 摘 要： | 依据１９８５－１９９５年国际有关资料对鱼类生长激素的分子生物学及其研究的最新成果与进展进行综合评述。研究表明，已完成鳗鲡等９种鱼类生长激素的氨基酸组成与全序列分析及大麻哈鱼等２０种鱼类的生长激素基因的分离与克隆，有些已在工程菌或动物细胞中的高效表达；鱼类生长激素基因的调控机制与生长激素的活性部位研究正在深入进行；将外源的生长上入鱼体或将外源的生长激素基因导入受体鱼，以期促进生长，增加抗性，是生长激
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| 关 键 词： | 鱼类 生长激素 分子生物学 基因 |
| 收稿时间： | 1995/8/30 0:00:00 |
| 修稿时间： | 4/5/1996 12:00:00 AM |
ADVANCES IN STUDIES ON MOLECULAR BIOLOGY AND APPLICATIONS OF FISH GROWTH HORMONE |
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| Xu Bin,Li Deshang and Zhang Peijun.ADVANCES IN STUDIES ON MOLECULAR BIOLOGY AND APPLICATIONS OF FISH GROWTH HORMONE[J].Oceanologia Et Limnologia Sinica,1997,28(5):553-557. |
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| Authors: | Xu Bin Li Deshang and Zhang Peijun |
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| Institution: | Open Laboratory on Aquacultural Research of the State Educational Committee of China,Ocean University of Qingdao,Qingdao 266003;Open Laboratory on Aquacultural Research of the State Educational Committee of China,Ocean University of Qingdao,Qingdao 266003;Institute of Oceanology , Chinese Academy of Sciences, Qingdao 266071 |
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| Abstract: | Based on 1985- 1995 published data, this paper reviews the advancesand latest results in studies on molecular biology and applicahons of flsh growthhormone (GH).Recently,the amino acid compositions and complete amino acidsequences of 9 fish GHs, such as those of eel, etc., were determined. About 20 fishGH genes, including chum salmon, ete., have been isolated and cloned, and somehave been expressed in engineering bacterium, yeast and edmal cells. Studies on theregulatory mechanism (s) of fish GH genes and bioactive domains in fish GH arebeing intensively carried out. In order to promote growth and increase diseaseresistance, the exogenous GH and GH genes are delivered and transferred to farmedfish. |
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| Keywords: | Fish Grwoth hormone (GH) Molecular biology Gene Application Advances |
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