| Immunotoxicity Effect of Benzo[α]Pyrene on Scallop Chlamys farreri |
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| 作者单位： | The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, P. R. China
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| 基金项目： | 青岛自然科学技术基金 |
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| 摘 要： | The toxic effects of benzoα]pyrene (Bα]P) at different concentrations (0.1, 0.5, 1, 2.5 and 7.5 ugL-1) on scallop (Chla-mys farreri) immune system were studied. The results showed that Ba]P had significant toxic effects on the haemocyte counts, neu-tral red uptake, phagocytosis, bacteriolytic and antibacterial activity (P<0.05), while the seawater control and acetone control had no significant differences. The haemocyte counts, neutral red uptake, phagocytosis and bacteriolvtic activity in all Bα]P treatment groups as well as antibacterial activity, in groups of 0.5, 1, 2.5 and 7.5 ugL-1 Bα]P decreased significantly (P<0.05). Some of these indices tended to be stable on the sixth day and others on the ninth day, and the indices showed clear time- and concentra-tion-response to Bα]P. Bacteriolytic activity in 0.1ugL-1 Bα]P treatment group and antibacterial activity in 0.1 ugL-1 and 0.5 ugL-1 Bα]P treatment groups increased at the beginning of exposure and reached their peaks on day 1 and day 6, respectively. Following that, both activities decreased gradually and became stable after day 9. When all the indices reached stability, they were significantly lower than those in control group (P<0.05), except for antibacterial activity in 0.1 ugL-1 Bα]P treatment group (P<0.05). Thus, Bα]P has evident toxic effects on scallop immune system, which supports the view that a relationship exists between pollution and immu-nomodulation in aquatic organisms.
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| 关 键 词： | benzo[α]pyrene (B[α]P) |
Immunotoxicity Effect of Benzo[α]Pyrene on Scallop Chlamys farreri |
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| Authors: | ZHANG Lin PAN Luqing LIU Jing |
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| Institution: | The Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, P. R. China |
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| Abstract: | The toxic effects of benzoα]pyrene (Bα]P) at different concentrations (0.1, 0.5, 1, 2.5 and 7.5 ugL-1) on scallop (Chla-mys farreri) immune system were studied. The results showed that Ba]P had significant toxic effects on the haemocyte counts, neu-tral red uptake, phagocytosis, bacteriolytic and antibacterial activity (P<0.05), while the seawater control and acetone control had no significant differences. The haemocyte counts, neutral red uptake, phagocytosis and bacteriolvtic activity in all Bα]P treatment groups as well as antibacterial activity, in groups of 0.5, 1, 2.5 and 7.5 ugL-1 Bα]P decreased significantly (P<0.05). Some of these indices tended to be stable on the sixth day and others on the ninth day, and the indices showed clear time- and concentra-tion-response to Bα]P. Bacteriolytic activity in 0.1ugL-1 Bα]P treatment group and antibacterial activity in 0.1 ugL-1 and 0.5 ugL-1 Bα]P treatment groups increased at the beginning of exposure and reached their peaks on day 1 and day 6, respectively. Following that, both activities decreased gradually and became stable after day 9. When all the indices reached stability, they were significantly lower than those in control group (P<0.05), except for antibacterial activity in 0.1 ugL-1 Bα]P treatment group (P<0.05). Thus, Bα]P has evident toxic effects on scallop immune system, which supports the view that a relationship exists between pollution and immu-nomodulation in aquatic organisms. |
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| Keywords: | Chlamys farreri haemocyte counts neutral red uptake phagocytosis bacteriolytic activity antibactenal activity |
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