| Association between multi-level inorganic arsenic exposure from drinking water and skin lesions in Inner Mongolia, China |
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| 作者姓名： | Xiaojuan GUO Yoshihisa Fujino Xiaolei YE Jun LIU Takesumi Yoshimura |
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| 作者单位： | [1]Department of Preventive Medicine, School of Environment andPublic Health, Wenzhou Medical College, Wenzhou 325035, China [2]Department of Preventive Medicine and Community Health, University of Occupational and Environmental Health, Japan [3]Center for Endemic Disease Control and Research oflnner Mongolia, Harbin 150086, China [4]Fukuoka Institute of Health and Environmental Sciences, Fukuoka, Japan |
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| 摘 要： | Arsenic is one of the most important single-substance toxicants in the environment. In Inner Mongolia of China, 300000 residents are believed to drink water containing 〉50 μg/L. Skin lesions have been known as the most common consequences resulting from chronic exposure to arsenic. To clarify the prevalence of arsenic-induced skin lesions, it is important to assess the impact of this problem on the target population, and to make future planning. We evaluated the association between multi-level inorganic arsenic exposure from drinking water and skin lesions in an arsenic-affected area in Inner Mongolia, China. 109 and 32 subjects fi＇om high-level arsenic-affected （〉5 μg/L） village and low-level （≤50 μg/L） village were recruited and had detailed physical examination with special emphasis on arsenic-related skin lesions. Arsenic exposure was measured for each participant with As concentration of primary well and the duration of using the well was recorded. Arsenic-induced skin lesions including keratosis, pigmentation, and/or leucomelanosis were diagnosed in 56 and 3 subjects in the two villages, respectively. Logistic regression was conducted to calculate prevalence-odd ratios of skin lesions by levels of arsenic exposure with adjustment of sex, age group, smoking and duration of exposure. A consistent dose-response relationship between arsenic exposure level and skin lesion risk was observed.
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| 关 键 词： | 砷 内蒙古 饮用水 水文化学 |
Association between multi-level inorganic arsenic exposure from drinking water and skin lesions in Inner Mongolia, China |
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| Xiaojuan GUO Yoshihisa Fujino Xiaolei YE Jun LIU Takesumi Yoshimura.Association between multi-level inorganic arsenic exposure from drinking water and skin lesions in Inner Mongolia, China[J].Chinese Journal of Geochemistry,2006,25(B08):73-73. |
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| Abstract: | |
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| Keywords: | arsenic exposure skin lesions dose-response relationship |
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