|
|||||
|
|
Biomarkers in croakers Micropogonias furnieri (Teleostei: Sciaenidae) from polluted and non-polluted areas from the Patos Lagoon estuary (Southern Brazil): evidences of genotoxic and immunological effects |
|
| Authors: | Amado Lílian Lund da Rosa Carlos Eduardo Leite Alice Meirelles Moraes Loraine Pires Wagner Vaz Pinho Grasiela L Leães Martins Camila Martinez Gaspar Robaldo Ricardo Berteaux Nery Luis Eduardo Maia Monserrat José Maria Bianchini Adalto Martinez Pablo Elias Geracitano Laura Alicia |
| Institution: | 1. Programa de Pós-Graduação em Oceanografia Biológica, Fundação Universidade Federal do Rio Grande, Av. Itália Km 8, Campus Carreiros, 96201-900, Rio Grande, RS, Brazil;2. Programa de Pós-Graduação em Ciências Fisiológicas—Fisiologia Animal Comparada, Fundação Universidade Federal do Rio Grande, Av. Itália Km 8, Campus Carreiros, 96201-900, Rio Grande, RS, Brazil;3. Curso de Graduação em Ciências Biológicas, Fundação Universidade Federal do Rio Grande, Av. Itália Km 8, Campus Carreiros, 96201-900, Rio Grande, RS, Brazil;4. Departamento de Ciências Fisiológicas, Fundação Universidade Federal do Rio Grande, Av. Itália Km 8, Campus Carreiros, 96201-900, Rio Grande, RS, Brazil |
| Abstract: | Biomarkers of exposure and effect of pollutants were analyzed in croakers Micropogonias furnieri (Teleostei: Sciaenidae) captured in winter and summer in a polluted and in a non-polluted site at the Patos Lagoon estuary (Southern Brazil). Catalase and glutathione S-transferase activities (exposure biomarkers) and lipid peroxidation (effect biomarker) were analyzed in liver samples. Other two effect biomarkers were also studied: blood cells DNA damage (through comet assay and micronucleus test) and respiratory burst measurements. In a broad view, results point to an important seasonal variation of the biochemical biomarkers analyzed. However, data obtained clearly indicate that croakers collected in winter at the polluted site were subjected to a level of clastogenic agents sufficient to generate irreversible genetic damages (mutations) and impair the fish immune system. |
| Keywords: | |
| 本文献已被 ScienceDirect PubMed 等数据库收录！ | |