| 人体卵巢癌中砂粒体矿化的矿物学研究 |
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| 引用本文： | 王长秋,杨若晨,鲁安怀,柳剑英,张 波.人体卵巢癌中砂粒体矿化的矿物学研究[J].岩石矿物学杂志,2009,28(6):617-622. |
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| 作者姓名： | 王长秋 杨若晨 鲁安怀 柳剑英 张 波 |
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| 作者单位： | 1. 造山带与地壳演化教育部重点实验室,北京大学,地球与空间科学学院,北京,100871
2. 北京大学,医学部,基础医学院病理学系,北京,100083 |
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| 基金项目： | 国家自然科学基金资助项目 |
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| 摘 要： | 以卵巢浆液性癌中砂粒体矿化为研究对象,采用偏光显微镜、扫描电镜及其能谱、X射线粉晶衍射、傅立叶变换红外光谱和高分辨透射电子显微镜,对原位和分离处理样品的表面形貌、结构和矿物成分进行了观察测试.结果表明,卵巢浆液性癌中砂粒体具同心层状结构,矿化物质由纳米尺寸水草酸钙石和碳羟磷灰石两种物相组成,前者沉积在砂粒体内部,结晶度相对较高,后者沉积在砂粒体外层,结晶度差.
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| 关 键 词： | 卵巢癌 砂粒体 碳羟磷灰石 水草酸钙石 |
Mineralogy of psammoma bodies in human ovarian cancer |
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| WANG Chang_qiu,YANG Ruo_chen,LU An_huai,LIU Jian_ying and ZHANG Bo.Mineralogy of psammoma bodies in human ovarian cancer[J].Acta Petrologica Et Mineralogica,2009,28(6):617-622. |
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| Authors: | WANG Chang_qiu YANG Ruo_chen LU An_huai LIU Jian_ying and ZHANG Bo |
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| Abstract: | Ovarian cancer is one of the common malignant tumors in female reproductive organs. Psammoma bodies occurring in cell population is considered to be a phenomenon of ovarian serous carcer. In this paper, psammoma bodies from ovarian serous carcinomas were investigated by using SEM, EDAX, XRD, FTIR and HRTEM. The results show that the mineralized matter of the psammoma bodies with the concentric lamellated structure is composed of nano-size whewellite and carbonate hydroxylapatite. The former is deposited in the inner part of the psammoma body in a relatively high crystallinity, whereas the latter in the outer part in a low crys-tallinity. |
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| Keywords: | ovarian cancer psammoma body carbonate hydroxylapatite whewellite |
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