| iDose4迭代重建在AIDS合并PJP患者胸部低剂量CT扫描中的应用研究 |
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| 引用本文： | 夏振营,孙君,王杏,吴丹,丁金立,李宏军.iDose4迭代重建在AIDS合并PJP患者胸部低剂量CT扫描中的应用研究[J].CT理论与应用研究,2020,29(2):195-202. |
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| 作者姓名： | 夏振营 孙君 王杏 吴丹 丁金立 李宏军 |
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| 作者单位： | 1. 首都医科大学附属北京佑安医院放射科, 北京 100069; |
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| 基金项目： | 国家自然科学基金:基于医疗影像深度学习的HIV脑认知模型及临床应用(61936013) |
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| 摘 要： | 目的:研究i Dose4迭代重建算法不同迭代水平在人类获得性免疫缺陷综合征(AIDS)合并耶氏肺孢子菌肺炎(PJP)患者胸部低剂量CT扫描中的效能对比。方法:应用飞利浦iCT对16例AIDS合并PJP患者分别行常规剂量和低剂量胸部CT平扫。常规剂量组的DRI指数设置为30;低剂量组的DRI指数设置为10。管电压均采用120 k V。常规剂量组采用FPB重建算法,低剂量组采用iDose4(L2,L4,L6)重建算法。测量不同扫描方案下图像的客观噪声值(SD),记录不同扫描方案下CT容积剂量指数(CTDI vol)、剂量长度乘积(DLP)并计算有效剂量(ED)。比较不同扫描方案下的辐射剂量、图像的客观指标(图像噪声)及主观指标(图像质量主观评分)的差异。结果:低剂量扫描条件下,LD_iDose4_L2组、LD_iDose4_L4组及LD_iDose4_L6图像噪声值分别为:12.41、10.13和8.01,LD_iDose4_L6组的图像噪声值与SD_FPB组(8.51)相比,差异无统计学意义。肺窗视图下,LD-iDose4_L2组、LD-iDose4_L4组CT图像质量主观评分均在3分以上,满足了诊断需求,以LD_iDose4_L2组显示最好。纵隔窗视图下,低剂量组各组主观评分均在3分以上,均满足了诊断需求,其中以LD_iDose4_L6组得分最高。低剂量组与常规组的ED值大小分别为6.18和2.28,差异均具有统计学意义(P<0.05),低剂量组的有效剂量较常规剂量组降低了63.11%。结论:iDose4迭代重建在AIDS合并PJP患者胸部CT病变及解剖结构的显示上具有明显的优势,能够在大幅降低辐射剂量的情况下得到满足诊断需要的CT图像。低剂量扫描条件下,iDose 4迭代重建迭代水平级别越高,降噪的能力越强,图像噪声值越小。但就图像总体质量而言,肺窗视图下,图像质量以LD_iDose4_L2组显示最好;纵隔窗视图下,图像质量以LD_iDose4_L6组显示最好。
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| 关 键 词： | X线断层摄影术 迭代重建 低剂量 耶氏肺孢子菌肺炎 辐射剂量 |
| 收稿时间： | 2019-11-14 |
Application of iDose4 Iterative Reconstruction on Low Dose CT Scanning in AIDS Patients with PJP |
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| Institution: | 1. Department of Radiology, Beijing Youan Hospital, Capital Medical University, Beijing 100069, China;2. Department of Radiology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China |
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| Abstract: | Objective:To study the efficacy of different iterative scales of iDose4 reconstruction algorithm in low dose chest CT scanning in AIDS patients with PJP. Methods:Sixteen AIDS patients with PJP underwent routine dose and low dose unenhanced chest CT scanning on Philips iCT. The DRI index of routine dose group and low dose group was 30 and 10, respectively. The tube voltage was 120 kV in two group. The reconstruction algorithms of routine dose group and low dose group were FPB and iDose 4(L2, L4, L6), respectively. The objective noise value, the CT dose index volume(CTDI) and dose length product(DLP) were recorded, while the effective dose(ED) was estimated. The radiation dose, the objective index of the image(image noise) and the subjective index(image quality subjective score) were compared. Results:The mean values of objective noise of LD_iDose4_L2 group, LD_iDose4_L4 group and LD_iDose4_L6 image were 12.41, 10.13 and 8.01, respectively. There was no significant difference in image noise scores between LD_iDose4_L6 group and SD_FPB group. For the lung images, the noise score of the CT image in the LD-iDose4_L2 group and the LD-iDose4_L4 group was more than 3 points, which met the needs of diagnosis. The LD_iDose4_L2 group showed the best image quality. For the mediastinum images, the subjective scores of all groups in the low-dose group were more than 3 points, which met the needs of diagnosis. The effective dose of low-dose group and the routine dose group were 6.18 and 2.28 respectively(P<0.05). The effective dose of the low dose group was reduced by 63.11% compared with the routine dose group. Conclusion:IDose 4 iteration reconstruction has obvious advantages in displaying chest CT lesions and anatomical structures in AIDS patients with PJP, which can provide CT images to meet diagnostic needs while dramatically reducing radiation dose. Under low-dose scanning conditions, the higher the level of iDose 4 iterative reconstruction iteration, the stronger the ability of noise reduction and the smaller the image noise value. But as far as the overall image quality is concerned, LD_iDose 4_L2 group shows the best image quality in lung window view and LD_iDose 4_L6 group shows the best image quality in mediastinal window view. |
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