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MDCT评价冠心病患者升主动脉弹性与高血压的相关性
引用本文:吴磊,查云飞,彭晓菁,付传明,密亚平.MDCT评价冠心病患者升主动脉弹性与高血压的相关性[J].CT理论与应用研究,2013(4):685-691.
作者姓名:吴磊  查云飞  彭晓菁  付传明  密亚平
作者单位:[1]湖北医药学院附属太和医院放射影像中心,湖北十堰442000 [2]武汉大学人民医院(湖北省人民医院)放射科,武汉430000
摘    要:目的:采用64-MDCT评价冠心病患者升主动脉弹性与高血压的相关性。方法:对135例拟诊冠心病的受检者行回顾性心电门控技术冠状动脉CTA和冠状动脉造影(CAG)检查。测量受试者血压,重组升主动脉0%~95%R-R间期间隔5%的图像,采用MATLAB软件自动描绘并测量各R—R间期主动脉横截面积,然后计算出升主动脉弹性值。将受试者分为非高血压组(n=54)和高血压组(n=81)。结果:高血压组升主动脉弹性低于非高血压组(t=7.81,P〈0.001)。多元线性回归表明高血压是升主动脉弹性值的独立影响因子(B=-0.835,t=7.18,P〈0.001)。结论:升主动脉弹性与高血压有较好的相关性,升主动脉弹性的及时、准确评价有助于心血管疾病的早期预警。

关 键 词:冠心病  主动脉弹性  高血压  MDCT

Relationship between Ascending Aortic Distensibility and Hypertension of CAD Patients Evaluated by MDCT
WU Lei,ZHA Yun-fei,PENG Xiao-jing,FU Chuan-mingj,MI Ya-ping.Relationship between Ascending Aortic Distensibility and Hypertension of CAD Patients Evaluated by MDCT[J].Computerized Tomography Theory and Applications,2013(4):685-691.
Authors:WU Lei  ZHA Yun-fei  PENG Xiao-jing  FU Chuan-mingj  MI Ya-ping
Institution:1.Department of Radiology, Affiliated Taihe Hospital, Hubei Medical College, Shiyan 442000, China 2.Department of Radiology, Affiliated Renmin Hospital of Wuhan Uniersity, Wuhan 430000, China
Abstract:Objective: To assess the relationship between ascending thoracic aorta distensibility and hypertension in coronary artery disease (CAD) patients by 64-multidetector computed tomography. Method: In all, 135 patients with suspected CAD were enrolled in this study and underwent retrospective ECG-gated coronary CTA and CAG. Every patient's blood pressure was measured before and after the coronary CTA respectively. The ascending aortal images of 20 phases between 0% and 95% of the R-R intervals with an increment of 5% was reformatted and the aortal area of the images was measured by MATLAB software, and then we can calculate the aortic distensibility. The patients can be divided into hypertension subjects (n = 81) and normal subjects (n = 54). Result: The aortic distensibility of the Patients was remarkably lower in hypertension subjects than that in normal subjects(t- 7.81% P〈 0.001). Multivariate linear regression demonstrated that hypertension was the independent risk thctors of aortic distensibility (B -0.835, t = 7.18, P 〈 0.001). Conclusion: The ascending thoracic aorta distensibility had a significant relationship with hypertension. The estimate of aortic distensibility may play an important role in the prediction of cardiovascular disease.
Keywords:coronary artery disease (CAD)  aortic distensibility  hypertension  MDCT
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