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基于CT成像的GBR术中两种植骨材料变化的比较分析
引用本文:王国世,魏明贵,李韶伟,沙烟直.基于CT成像的GBR术中两种植骨材料变化的比较分析[J].CT理论与应用研究,2014(5):843-850.
作者姓名:王国世  魏明贵  李韶伟  沙烟直
作者单位:上海市静安区中心医院(复旦大学附属华山医院静安分院)口腔科,上海200040
基金项目:上海市卫生计生委科研项目(20114129).
摘    要:目的:利用CT扫描提供的图像信息与数据,运用Simplant软件分析系统,对GBR术中植入的天博骨粉(Bio—Osten)与Bio—Oss骨粉材料在引导骨生长过程中的体积变化进行定量比较分析,探讨天博骨粉的成骨状况。方法:选取15例前牙即刻种植同时实施GBR术的患者,随机分为两组,其中天博骨粉组(实验组)7例,Bio—Oss骨粉组(对照组)8例。在完成牙种植体植入的同时,植入天博骨粉或Bio-Oss骨粉,分别于术后1周、3个月、6个月进行种植区螺旋CT扫描,利用CT扫描提供的图像信息,运用Simplant软件分析系统,分别对即刻种植的GBR术后1周、3个月、6个月的天博骨粉、Bio—Oss骨粉的体积进行测量,计算其术后3个月、6个月时相对术后1周时骨粉的吸收率,并运用SPSS16.0统计软件包进行统计分析。结果:术后1周天博组、Bio—Oss组植入骨粉的平均体积分别为:101.10mm^3±14.76mm^3、121.69mm^3±38.35mm^3,两者无统计学意义(P〉0.05);术后3个月天博组、Bio—Oss组吸收率分别为:41.51%±5.87%、49.30%±5.78%,差异有统计学意义(P〈0.05);术后6个月,两者吸收率分别为:58.02%±5.67%、70.26%±10.64%,差异有统计学意义(P〈0.05)。结论:在CT影像上,天博骨粉与Bio—Oss骨粉有着相似的引导成骨性和可吸收性;相比较而言,天博骨粉的吸收速率慢于Bio—Oss骨粉,或者可能是Bio—Oss骨粉引导新骨生长速度快于天博骨粉。

关 键 词:螺旋CT  天博骨粉  Bio—Oss骨粉  三维重建  引导骨再生

Comparison between Two Materials of Bone Graft in Guided Bone Regeneration by CT Image Analysis
WANG Guo-shi,WEI Ming-gui,LI Shao-wei,SHA Yan-zhi.Comparison between Two Materials of Bone Graft in Guided Bone Regeneration by CT Image Analysis[J].Computerized Tomography Theory and Applications,2014(5):843-850.
Authors:WANG Guo-shi  WEI Ming-gui  LI Shao-wei  SHA Yan-zhi
Institution:( Department of Stomatology, Jingan District Central hospital of shanghai (Huashan Hospital Fudan University Jingan Branch), Shanghai 200040, China)
Abstract:Objective: To compare the changes between Bio-Osten bone meal and Bio-Oss bone meal during the period of guided bone regeneration (GBR) in immediate implanting according to the data from the image by spiral CT scan. Methods: 15 patients who receive immediate implanting and GBR process in anterior teeth, were divided randomly into two groups including experimental group (Bio-Osten bone grafts, n = 7) and control group (Bio-Oss, n = 8). During dental implanting, the two groups were used Bio-Osten bone meal and Bio-Oss bone meal respectively and took spiral CT to scan the implanting area in 1 week, 3 months, 6 months after the procedures. According to the information from the image by CT scan, the volumes of bone meal in both groups were measured using Simplant analysis system .The remaining volume ratios were calculated in two groups in 3 months, 6 months after the procedures and analyzed statistically between two groups by the SPSS 16.0. Results: 3 months after operation, the absorption ratios were 41.51% ± 5.87%, 49.30% ± 5.78% in Bio-Osten group and Bio-Oss group, respectively. 6 months after operation, the absorption ratios were 58.02%±5.67%, 70.26%± 10.64%, respectively. There were significant difference between two groups (P 〈 0.05) in both 3 months and 6 months. Conclusion: According to CT image, Bio-Osten and Bio-Oss have similar role in bone induction and similar biological absorption. In comparison, Bio-Osten was absorpted more slowly than Bio-Oss. Maybe Bio-Oss guided bone regeneration faster than Bio-Osten.
Keywords:spiral CT  Bio-Osten  Bio-Oss  3-D reconstruction  GBR
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