Subcellular Distribution of Heavy Metals in Organs of BivalveModiolus Modiolus Living Along a Metal Contamination Gradient |
| |
| Authors: | Olga V Podgurskaya Victor Ya Kavun |
| |
| Institution: | (1) Institute of Marine Biology, Far East Branch, Russian Academy of Sciences, 690041 Vladivostok, Russia |
| |
| Abstract: | Concentration and distribution of Fe, Zn, Cu, Cd, Mn, Pb, Ni among subcellular fractions (cellular membrane structures and
cytosol) and Zn, Cu, Cd among cytoplasmic proteins in the kidney and digestive gland of musselModiolus modiolus living along a polymetallic concentration gradient were studied. It was found in the kidney ofM. modiolus from contaminated sites that the Fe percent increased in the “membrane” fraction, whereas Zn, Pb, Ni and Mn percent increased
in the cytosol compared to the kidney of the control mussel. Note kidney cytosol ofM. modiolus from clean and contaminated sites sequestered major parts of Cu and Cd. In the digestive gland ofM. modiolus from contaminated sites Fe, Zn, Cd, Mn, Ni percent increased in the “membrane” fraction, whereas Cu, Pb percent increased
in the cytosol compared to digestive gland of control mussel. Gel-filtration chromatography shows kidney ofM. modiolus contains increased metallothionein-like protein levels irrespective of ambient dissolved metal concentrations. It was shown
that the metal detoxification system in the kidney and digestive gland ofM. modiolus was efficient under extremely high ambient metal levels. However, under complex environmental contamination in the kidney
ofM. modiolus, the metal detoxification capacity of metallothionein-like proteins was damaged. |
| |
| Keywords: | heavy metals subcellular distribution metalbinding proteins contamination |
| 本文献已被 SpringerLink 等数据库收录！ |
|
