Susceptibility to genetic damage and cell types in Mediterranean mussels |
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| Authors: | Dolcetti L Venier P |
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| Institution: | University of Padova, Department of Biology, Italy. |
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| Abstract: | Micronucleus (MN) frequency is generally accepted as a marker of chromosomal damage and has been studied in a variety of cells and species. In previous work, we detected significant dose-related MN increases in the epithelial-like gill cells and agranular haemocytes of Mytilus galloprovincialis treated with benzoa]pyrene, a well-known mutagenic pollutant. In addition, we have studied micronuclei and other nuclear abnormalities in mussels collected from the Venice lagoon (Italy). Frequency changes, possibly related to genotoxic/toxic stress, in both granular and micronucleated cells from gills and haemolymph, were detected. Environmental data suggest the effect of genotoxic pollutants and the importance of cell replication in the interpretation of micronucleus frequencies. |
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| Keywords: | Mytilus Genotoxic pollutants Micronuclei Nuclear abnormalities Cell replication |
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