| UV-B辐射增强对泥鳅红细胞遗传毒理学指标的影响研究 |
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| 引用本文： | 李美芹,肖慧,唐学玺.UV-B辐射增强对泥鳅红细胞遗传毒理学指标的影响研究[J].中国海洋大学学报(自然科学版),2007,37(3):453-456,448. |
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| 作者姓名： | 李美芹 肖慧 唐学玺 |
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| 作者单位： | 中国海洋大学生态学实验室,山东,青岛,266003 |
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| 基金项目： | 国家自然科学基金;新世纪优秀人才支持计划奖励基金 |
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| 摘 要： | 利用红细胞微核和核异常的遗传毒理学方法,研究UV-B辐射增强对泥鳅红细胞核的细胞遗传毒性效应,评价2种毒理学指标在UV-B辐射监测应用中的可行性。结果显示,随着UV-B辐射剂量的加大,泥鳅红细胞的微核细胞率持续上升,表现出明显的剂量-效应关系,微核细胞率与辐射剂量显著正相关。而泥鳅红细胞核异常率随着UV-B辐射剂量的加大无规律性的变化,没有表现出剂量-效应关系,核异常率与辐射剂量无相关性。脱离UV-B辐射处理6 d后泥鳅红细胞的微核细胞率不能够恢复正常的对照水平,而核异常细胞率随着时间的延长,逐渐得以恢复。结果指示泥鳅红细胞微核率是用于UV-B辐射监测的灵敏和可行的细胞遗传毒理学指标,而核异常率不能用于UV-B辐射的监测。
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| 关 键 词： | 泥鳅 微核率 核异常率 UV-B辐射 |
| 文章编号： | 1672-5174（2007）03-453-05 |
| 修稿时间： | 2006-08-012006-10-09 |
A Study on the Effect of UV-B Radiation Enhancement on the Indicators of Cytogenetic Toxicology in Misgurnus anguillicaudatus |
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| LI Mei-Qin,XIAO Hui,TANG Xue-Xi.A Study on the Effect of UV-B Radiation Enhancement on the Indicators of Cytogenetic Toxicology in Misgurnus anguillicaudatus[J].Periodical of Ocean University of China,2007,37(3):453-456,448. |
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| Authors: | LI Mei-Qin XIAO Hui TANG Xue-Xi |
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| Institution: | The Ecology Laboratory, Ocean University of China, Qingdao 266003, China |
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| Abstract: | The cytogenetic toxicity effect of UV-B radiation enhancement on the erythrocytes of Misgurnus anguillicaudatus was studied by using micronuclei and nuclear anomalies tests,and the feasibility of UV-B radiation monitoring by means of the two tests was evaluated.The results showed that the micronuclei frequency increased continuously with the increase of UV-B radiation,and there was a significant correlation between frequencies of micronuclei and UV-B radiation dose.The frequencies of nuclear anomalies exhibited irregular changes with the increasing UV-B radiation,there was no relationship between the frequency of nuclear anomalies and UV-B radiation dose.The frequency of nuclear anomalies could recover to the control level 6 days after the removal of UV-B radiation,while the frequency of micronuclei could not.Therefore, the frequency of micronuclei was a sensitive and feasible cytogenetic indicator to monitor and assess the UV-B radiation status,but the frequency of nuclear anomalies could not be used to do so. |
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| Keywords: | Misgurnus anguillicaudatus frequency of micronuclei frequency of nuclear anomalies UV-B radiation |
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