| 鱼类维生素D3代谢及其生理功能的研究进展 |
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| 引用本文： | 万敏,邵锐.鱼类维生素D3代谢及其生理功能的研究进展[J].中国海洋大学学报(自然科学版),2021(2). |
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| 作者姓名： | 万敏 邵锐 |
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| 作者单位： | 中国海洋大学水产学院;青岛海洋科学与技术试点国家实验室 |
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| 基金项目： | 国家自然科学基金项目(31972802);山东省自然科学基金项目(ZR2019MC041);青岛海洋科学与技术试点国家实验室海洋渔业科学与食物产出过程功能实验室渔业科技青年人才计划项目(2018-MFS-T11)资助。 |
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| 摘 要： | 维生素D(VD)是一类具有抗佝偻病作用的类固醇激素,其中维生素D3(VD3)是VD在动物体内的主要存在形式。作为生命活动必不可少的一类物质,VD发挥着广泛且重要的生理学作用。VD在动物体内的代谢过程及相关的代谢酶具有较高的进化保守性,同时也受到多种因素的调控影响。由于鱼类在生活环境方面与陆生脊椎动物存在显著差异,VD在鱼类中的合成代谢及生理功能与高等动物也存在一定的区别。本文主要概述了鱼类VD3的主要来源以及需求量的研究,总结了近年来鱼类维生素D受体(VDR)、VD3代谢调控及其生理功能的研究进展,比较了鱼类和陆生高等动物在VD来源、代谢以及VDR等方面的差异,并对水生动物VD的未来研究方向进行了展望。
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| 关 键 词： | 维生素D3 25-羟基维生素D3 1α 25-二羟基维生素D3 维生素D受体(VDR) 代谢调控 鱼类营养 |
Research Progresses in Metabolism and Physiological Functions of Vitamin D3 in Fish Species |
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| WAN Min,SHAO Rui.Research Progresses in Metabolism and Physiological Functions of Vitamin D3 in Fish Species[J].Periodical of Ocean University of China,2021(2). |
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| Authors: | WAN Min SHAO Rui |
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| Institution: | (College of Fisheries, Key Laboratory of Aquaculture Nutrition and Feed, Ministry of Agriculture and Rural Affairs, Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, China;Pilot National Laboratory for Marine Science and Technology(Qingdao), Qingdao 266237, China) |
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| Abstract: | Vitamin D(VD)is a steroid hormone with anti-rickets effect,and vitamin D3(VD3)is mainly found in animals.As an essential substance for life activities,VD plays an extensive and important physiological role.The process of VD metabolism and the metabolic enzymes are evolutionally conserved,and also affected by various factors.Due to the significant differences between fish species and terrestrial vertebrates in living environments,the anabolism and physiological functions of VD in fish display some differences from those in terrestrial higher animals.In this review,we summarized the main origin and requirements of VD3 in fish,and concluded the recent advances in vitamin D receptor(VDR),the regulations of metabolic process of VD3 and its physiological functions in animals.Moreover,we compared the difference between fish and terrestrial higher vertebrates in VD origin,metabolism and VDR.At the end,the future research of VD in aquatic animals is prospected. |
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| Keywords: | vitamin D3 25-hydroxy vitamin D3 lα 25-dihydroxy vitamin D3 vitamin D receptor metabolic regulation fish nutrition |
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