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纳米金表面修饰与表面等离子体共振传感器的相互作用研究
引用本文:郝鹏,吴一辉,张平.纳米金表面修饰与表面等离子体共振传感器的相互作用研究[J].海洋学报,2010,32(9):6532-6537.
作者姓名:郝鹏  吴一辉  张平
作者单位:中国科学院长春光学精密机械与物理研究所 应用光学国家重点实验室, 长春 130033) (2009年10月29日收到,2010年1月29日收到修改稿) 为了分析纳米金表面修饰对表面等离子体共振(SPR;中国科学院长春光学精密机械与物理研究所 应用光学国家重点实验室, 长春 130033) (2009年10月29日收到,2010年1月29日收到修改稿) 为了分析纳米金表面修饰对表面等离子体共振(SPR;中国科学院长春光学精密机械与物理研究所 应用光学国家重点实验室, 长春 130033) (2009年10月29日收到,2010年1月29日收到修改稿) 为了分析纳米金表面修饰对表面等离子体共振(SPR
基金项目:国家自然科学基金(批准号:60971025)和国家高技术研究发展计划(863计划)(批准号:2007AA042102 )资助的课题.
摘    要:

关 键 词:表面等离子体共振  生物传感器  纳米金  金属膜

Study of interaction of surface plasmon resonance sensor with nano-gold
Hao Peng,Wu Yi-Hui and Zhang Ping.Study of interaction of surface plasmon resonance sensor with nano-gold[J].Acta Oceanologica Sinica (in Chinese),2010,32(9):6532-6537.
Authors:Hao Peng  Wu Yi-Hui and Zhang Ping
Institution:National Key Lab of Applied Optics, Changchun Institute of Optics,Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China;National Key Lab of Applied Optics, Changchun Institute of Optics,Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China;National Key Lab of Applied Optics, Changchun Institute of Optics,Fine Mechanics and Physics, Chinese Academy of Sciences, Changchun 130033, China
Abstract:For a quantitative analysis of the detection performance of wavelength surface plasmon resonance sensor after the introduction of absorbing thin films, a mathematical model was established for the wavelength SPR biosensor. Based on absorption theory of dispersive media, the distribution of electromagnetic field in each film outside the prism is calculated. The results show that, after introducing the absorbing thin films, electromagnetic field energy distribution in each layer out of the prism surfaces was changed, the metal film contribution on the resonance absorption was reduced, which increases the half wave width of SPR curve and the minimum reflection coefficient, so the optimal film thickness of metal film was also changed. Then the effect of colloidal gold and immunogold on SPR biosensor has been theoretically and experimentally verified. The result shows that, compared with the 48 nm gold film SPR sensor, the sensitivity increases 1.5 times when 45nm gold film is surface-modified with 10nm nano-gold.
Keywords:surface plasmon resonance  biosensors  nano-gold  metal films
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