| 半胱胺盐酸盐和LHRH-A对黄鳍鲷生长激素分泌的影响 |
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| 引用本文： | 石和荣,张为民,刘晓春,柯浩,林浩然.半胱胺盐酸盐和LHRH-A对黄鳍鲷生长激素分泌的影响[J].海洋学报,2005,27(3):147-153. |
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| 作者姓名： | 石和荣 张为民 刘晓春 柯浩 林浩然 |
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| 作者单位： | 1.中山大学, 水生经济动物研究所, 广东省水生经济动物良种繁育重点实验室, 广东, 广州, 510275;广东省农科院, 兽医研究所, 广东, 广州, 510640 |
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| 基金项目： | 广东省科技厅农业攻关项目资助(C20710)，国家自然科学基金农业倾斜项目资助(39970586)，广东省科技计划项目资助(A3050261)，教育部科学技术研究重点项目资助(02150). |
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| 摘 要： | 研究了生长抑素抑制剂半胱胺盐酸盐(CSH)和促黄体素释放激素类似物(LHRH-A)对黄鳍鲷生长激素(GH)分泌的影响.黄鳍鲷垂体GH含量在单独注射不同剂量CSH(25,50,100μg/gb.w)后2h均显著提高,注射后24h恢复正常.黄鳍鲷血清中GH水平在注射CSH(100μg/gb.w)后2h和CSH(25,50μg/gb.w)后6h均明显提高.单独注射LHRH-A(0.1μg/gb.w)后2h黄鳍鲷垂体GH含量和血清中GH水平均明显提高.注射CSH和LHRH-A后6h垂体GH含量明显高于单独注射CSH或LHRH-A,而血清GH水平在注射后12h明显高于单独注射CSH或LHRH-A.结果表明CSH和LHRH-A都能明显刺激黄鳍鲷垂体合成和释放GH,并且与CSH作用存在剂量依存关系,CSH和LHRH-A联合注射比单独注射作用更明显,作用的时间更持久.
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| 关 键 词： | 半胱胺盐酸盐 促黄体素释放激素类似物 黄鳍鲷 生长激素 |
| 文章编号： | 0253-4193(2005)03-0147-07 |
| 收稿时间： | 3/3/2004 12:00:00 AM |
| 修稿时间： | 2004/8/11 0:00:00 |
Effects of cysteamine hydrochloride and luteinizing hormone-releasing hormone analog on growth hormone secretion in Yellow-Fin Porgy |
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| SHI He-rong,ZHANG Wei-min,LIU Xiao-chun,KE Hao and LIN Hao-ran.Effects of cysteamine hydrochloride and luteinizing hormone-releasing hormone analog on growth hormone secretion in Yellow-Fin Porgy[J].Acta Oceanologica Sinica (in Chinese),2005,27(3):147-153. |
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| Authors: | SHI He-rong ZHANG Wei-min LIU Xiao-chun KE Hao and LIN Hao-ran |
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| Institution: | SHI He-rong~ |
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| Abstract: | Effects of cysteamine hydrochloride (a somatostatin-inhibiting agent,CSH) and luteinizing hormone-releasing hormone analog on growth hormone secretion in Sparus latus were investigated by i.p.injection.The pituitary GH contents of Sparus latus were significantly increased 2 hposti.p.injection of CSH with doses of 25,50 and 100 g/gb.w,and returned to control levels 24 h post injection.The serum GH levels of Sparus latus were significantly increased 2 h post injection of CSH with dose of 100 g/gb.w,and 6 h post injection of CSH with doses of 25 and 50 g/gb.w; LHRH- A(0.1 g/gb.w) significantly increased pituitary GH contents and serum GH levels 2 h post injection.Combining injection of LHRH-A and CSH significantly increased pituitary GH contents 6 h post injection as compared with CSH or LHRH-A alone,and the serum GH levels were significantly increased 12 h post injection as compared with CSH or LHRH-A alone.These results indicate that both CSH and LHRH-A could stimulate the synthesis and release of GH in Sparuslatus,and the effects of CSH were dose dependent.The combined effects of CSH and LHRH-A were significantly higher than those of CSH or LHRH-A alone. |
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| Keywords: | cysteamine hydrochloride(CSH) LHRH-A Sparus latus growth hormone |
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