The asymmetric or periodically varying blade loads resulted by wind shear become more significant as the blade length is increased to capture more wind power. Additionally, compared with the onshore wind turbines, their offshore counterparts are subjected to additional wave loadings in addition to wind loadings within their lifetime. Therefore, vibration control and fatigue load mitigation are crucial for safe operation of large-scale offshore wind turbines. In view of this, a multi-body model of an offshore bottom-fixed wind turbine including a detailed drivetrain is established in this paper. Then, an individual pitch controller (IPC) is designed using disturbance accommodating control. State feedback is used to add damping in flexible modes of concern, and a state estimator is designed to predict unmeasured signals. Continued, a coupled aero-hydro-servo-elastic model is constructed. Based on this coupled model, the load reduction effect of IPC and the dynamic responses of the drivetrain are investigated. The results showed that the designed IPC can effectively reduce the structural loads of the wind turbine while stabilizing the turbine power output. Moreover, it is found that the drivetrain dynamic responses are improved under IPC.