| 两种卵巢肿瘤中砂粒体的矿物学研究 |
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| 引用本文： | 孟繁露,王长秋,李艳,鲁安怀,梅放,柳剑英.两种卵巢肿瘤中砂粒体的矿物学研究[J].地学前缘,2013,20(3):154-160. |
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| 作者姓名： | 孟繁露 王长秋 李艳 鲁安怀 梅放 柳剑英 |
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| 作者单位： | 1. 造山带与地壳演化教育部重点实验室;北京大学地球与空间科学学院,北京100871
2. 北京大学医学部基础医学院病理学系,北京,100083 |
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| 摘 要： | 砂粒体是病理诊断中常见的钙化形式，与肿瘤关系密切。选取具有砂粒体矿化物的6例卵巢浆液癌和2例成熟性囊性畸胎瘤样品，采用POM、ESEM、EDX、TEM、μ SRXRD和μ SRXRF等研究方法，对原位和分离处理后的砂粒体进行了观察测试。结果表明，两种卵巢肿瘤中的砂粒体由粒状和短柱状矿物分层集合而成，其形成与胶原纤维关系密切。卵巢浆液癌和畸胎瘤中的砂粒体最大直径分别为35 μm、70 μm，主要矿物成分分别为碳羟磷灰石Ca5［PO4,CO3］3(OH)、羟基磷灰石Ca5(PO4)3(OH)。砂粒体中还含有Na、Mg、Zn、Fe、Sr、Cu等微量元素，Zn可替代Ca进入矿物晶格。
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| 关 键 词： | 砂粒体 矿化 卵巢浆液癌 畸胎瘤 |
| 收稿时间： | 2013-03-30 |
| 修稿时间： | 2013-04-23 |
Mineralogy of psammoma bodies in two types of ovarian tumors |
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| MENG Fanlu,WANG Changqiu,LI Yan,LU Anhuai,MEI Fang,LIU Jianying.Mineralogy of psammoma bodies in two types of ovarian tumors[J].Earth Science Frontiers,2013,20(3):154-160. |
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| Authors: | MENG Fanlu WANG Changqiu LI Yan LU Anhuai MEI Fang LIU Jianying |
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| Institution: | 1.Key Laboratory of Orogenic Belts and Crustal Evolution,MOE;School of Earth and Space Sciences,Peking University,Beijing 100871,China 2.Pathology Department,School of Basic Medical Science,Health Science Center of Peking University,Beijing 100083,China |
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| Abstract: | Psammoma body is a common form of calcification in pathological diagnosis and has close relevance to tumors.This paper focuses on mineralization in two types of ovarian tumors,ovarian serous cancer(6 cases) and teratoma(2 cases),using mineralogical research methods,such as POM,ESEM,EDX,TEM,μ-SRXRD and μ-SRXRF to investigate the psammoma bodies both in the tissue and separated.The results show that psammoma body consists of round and short column minerals which assembled lamellately.Its formation is closely related to collagenous fibers.In ovarian serous cancer and teratoma,the maximum diameters of the psammoma bodies are 35 μm and 70 μm respectively,and the main mineral compositions are carbonate hydroxyapatite(Ca5PO4,CO3]3(OH)) and hydroxyapatite(Ca5(PO4)3(OH)) respectively.There is also Na,Mg,Zn,Fe,Sr,Cu and other elements in psammoma bodies.Zn can take place of Ca in the crystal lattices. |
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| Keywords: | psammoma body mineralization ovarian serous cancer teratoma |
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