| Fluorosis and arsenicosis： An update |
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| 作者姓名： | Lakshmi Narasimharao Kodali Jagadiswararao Ramayanam |
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| 作者单位： | Dept. of Geology, S. V. University, Tirupati-517 502, A.P, India |
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| 摘 要： | Endemic fluorosis, caused by excess fluoride in water, is widespread in the arid and semiarid tracts of India. This disorder is of recent origin and developed due to certain faulty water management practices. After Eager reported ‘dental mottling＇ among emigrants from Pozzuli in Italy in 1901, several such reports came from all over the world. From 3 works published independently from Pennsylvania, Arizona and South Africa in 1931, it was known that this disorder is caused by drinking water containing over 1 mg/L fluoride during formation of permanent teeth among children.‘Skeletal fluorosis/Osteofluorosis＇, affecting bones and joints among adults was reported by Moeller and Gudjonsson in 1932 due to accumulation of fluoride in hard tissues by drinking water with over 7 mg/L fluoride for several years. In course of time fluorosis has been reported in over 22 countries from all over the world. Fluorosis spreads now among 67 million people in the entire arid and semiarid tracts of India. The work of National Institute of Nutrition of India at Hyderabad in 1977 revealed the spread of endemic ‘genu valgum＇ （knock-knee） crippling lower limbs right from childhood in association with fluorosis in most parts of India. Although preliminary work revealed that genu valgum is caused by drinking waters poor in calcium and rich in molybdenum, efforts these disorders by supplying low-fluoride water should be taken up to know its exact cause to the communities could not so eradicate The governmental efforts to eradicate the problem.
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| 关 键 词： | 氟中毒 骨骼 膝部关节 地方病 |
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