| Effects of benzo（a）pyrene exposure on the antioxidant enzyme activity of scallop Chlamysfarreri |
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| 引用本文： | 潘鲁青,任加云,郑德斌.Effects of benzo（a）pyrene exposure on the antioxidant enzyme activity of scallop Chlamysfarreri[J].中国海洋与湖沼学报,2009,27(1). |
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| 作者姓名： | 潘鲁青 任加云 郑德斌 |
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| 作者单位： | Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, China
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| 基金项目： | Supported by the Technology Development Program of Shandong (No. 2008GG1005010);;the Program of Introducing Talents of Discipline of Universities (111 Project, No. B08049) |
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| 摘 要： | Scallop Chlamys farreri was exposed to different concentrations of benzo(a)pyrene (BaP) (0.5 μg/L, 1.0 μg/L, 10.0 μg/L and 50.0 μg/L) for 30 days in seawater. The 7-ethoxyresorufin O-deethylase (EROD) activity was significantly induced, and increased with the increasing BaP concentration. The glutathione-S-transferase (GST), superoxide dismutase (SOD), catalase (CAT), Glutathione peroxidase (GPx) activities increased in short time at low concentration of BaP, and was significantly depressed at high concentr...
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| 关 键 词： | 抗氧化酶活性 栉孔扇贝 谷胱甘肽过氧化物酶 超氧化物歧化酶 MDA含量 生物标志物 浓度增加 苯 |
Effects of benzo(a)pyrene exposure on the antioxidant enzyme activity of scallop Chlamys farreri |
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| PAN Luqing,REN Jiayun,ZHENG Debin Key Laboratory of Mariculture,Ministry of Education,Ocean University of China,Qingdao ,China.Effects of benzo(a)pyrene exposure on the antioxidant enzyme activity of scallop Chlamys farreri[J].Chinese Journal of Oceanology and Limnology,2009,27(1). |
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| Authors: | PAN Luqing REN Jiayun ZHENG Debin Key Laboratory of Mariculture Ministry of Education Ocean University of China Qingdao China |
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| Institution: | Key Laboratory of Mariculture, Ministry of Education, Ocean University of China, Qingdao 266003, China |
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| Abstract: | Scallop Chlamys farreri was exposed to different concentrations of benzo(a)pyrene (BaP) (0.5 μg/L, 1.0 μg/L, 10.0 μg/L and 50.0 μg/L) for 30 days in seawater. The 7-ethoxyresorufin O-deethylase (EROD) activity was significantly induced, and increased with the increasing BaP concentration. The glutathione-S-transferase (GST), superoxide dismutase (SOD), catalase (CAT), Glutathione peroxidase (GPx) activities increased in short time at low concentration of BaP, and was significantly depressed at high concentrations. Scallop gill was more sensitive to BaP than the digestive gland, and the digestive gland was the main tissue to deal with oxyradicals. The contents of malondialdehyde (MDA) increased with the exposure time and there was a positive correlation (concentration-effect) between the MDA content and the concentration of BaP. The biomarkers determined in this experiment had important roles in detoxification, and showed great potential as biomarkers for oxidative stress. Controlled laboratory experiments designed to simulate field exposure scenarios are particularly useful in ascertaining biomarkers suitable for use with complex contaminant mixtures in the marine environment. |
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| Keywords: | benzo(a)pyrene Chlamys farreri biomarkers biotransformation detoxification mechanism |
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