Proteomic analysis of acute responses to copper sulfate stress in larvae of the brine shrimp, Artemia sinica |
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| Authors: | Qian Zhou Changgong Wu Bo Dong Fuhua Li Fengqi Liu Jianhai Xiang |
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| Institution: | (1) College of Marine Life Sciences, Ocean University of China, Yushan Road No.5, Qingdao, 266003, China;; |
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| Abstract: | Proteomics was used to reveal the differential protein expression profiles of acute responses to copper sulfate exposure in
larvae of Artemia sinica. Fourteen differentially displayed protein spots were detected and seven of them were identified. Three spots were up-expressed
and identified: actin, heat shock protein 70, and chaperone subunit 1; three down-regulated proteins were identified: arginine
kinase, elongation factor-2, and glycine-rich protein; and a newly expressed protein was identified as peroxiredoxin. The
study indicates the involvement of all the differentially expressed proteins in the early responses of protein expression,
and in the survival of A. sinica in the presence of copper and other heavy metals; the findings improve understanding of the organism’s adaptive responses
and resistance. |
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