Characterization of DYRK2 (dual-specificity tyrosine-phosphorylation-regulated kinase 2) from Zebrafish (Dario rerio) |
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| Authors: | SUN Wei TAN Xungang ZHANG Peijun ZHANG Yuqing XU Yongli Institute of Oceanology Chinese Academy of Sciences Qingdao China Graduate School Beijing |
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| Institution: | SUN Wei,TAN Xungang,ZHANG Peijun**,ZHANG Yuqing,XU Yongli Institute of Oceanology,Chinese Academy of Sciences,Qingdao 266071,China,Graduate School,Beijing 100039 |
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| Abstract: | Proteins of the DYRK(dual-specificity tyrosine-phosphorylation-regulated kinase) family are characterized by the presence of a conserved kinase domain and N-terminal DH box.DYRK2 is involved in regulating key developmental and cellular processes,such as neurogenesis,cell proliferation,cytokinesis,and cellular differentiation.Herein,we report that the ortholog of DYRK2 found in zebrafish shares about 70% identity with that of human,mouse,and chick.RT-PCR showed that DYRK2 is expressed maternally and zygotica... |
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| Keywords: | zebrafish DYRK2 in-situ hybridization muscle development |
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