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1.
目的 通过研究烟草烟雾暴露对哮喘大鼠气道组蛋白去乙酰化酶(histone deacetylase,HDAC)2以及血浆、支气管肺泡灌洗液(BALF)中干扰素(interferon,IFN)-γ、白细胞介素(interleukin,IL)-4表达的影响,探讨HDAC2在辅助性T淋巴细胞(T helper cell)Th1/Th2平衡中的作用。方法 50只雄性Wistar大鼠随机分为对照组、哮喘组、烟雾暴露+哮喘组、布地奈德+哮喘组、布地奈德+烟雾暴露+哮喘组,建立哮喘大鼠模型、哮喘大鼠烟雾暴露模型以及布地奈德干预模型。免疫组织化学法检测各组大鼠气道HDAC2蛋白的表达,酶联免疫吸附试验法(ELISA)检测血浆和BALF中Th1型特征性细胞因子IFN-γ以及Th2型特征性细胞因子IL-4水平。结果 与对照组相比,烟雾暴露+哮喘组、哮喘组大鼠气道HDAC2蛋白表达降低,与哮喘组相比,烟雾暴露+哮喘组大鼠气道HDAC2蛋白表达降低,差异均有统计学意义(P均<0.05)。与布地奈德+哮喘组相比,布地奈德+烟雾暴露+哮喘组大鼠气道HDAC2蛋白表达降低,差异有统计学意义(P<0.05);与对照组相比,哮喘组大鼠和烟雾暴露+哮喘组大鼠血浆、BALF中IFN-γ表达减少,IL-4表达增加,差异均有统计学意义(P均<0.01);与哮喘组相比,烟雾暴露+哮喘组大鼠血浆、BALF中IFN-γ表达减少,IL-4表达增加,差异均有统计学意义(P均<0.01);与布地奈德+哮喘组相比,布地奈德+烟雾暴露+哮喘组大鼠血浆、BALF中IFN-γ表达减少,IL-4表达增加,差异均有统计学意义(P均<0.01);肺组织HDAC2蛋白的表达与血浆中IFN-γ表达呈正相关(r=0.533,P<0.01),与IL-4表达呈负相关(r=-0.642,P<0.01)。结论 烟草烟雾暴露可以下调哮喘大鼠模型肺组织HDAC2蛋白的表达,从而影响气道炎症,IFN-γ、IL-4的表达以及布地奈德的治疗效果,这可能是烟草烟雾恶化哮喘气道Th 1/Th2平衡的一个免疫学机制。  相似文献   

2.
周侠  游娜  徐家蓉  缪珩 《寒旱区科学》2017,9(5):140-145
目的 探讨2型糖尿病(T2DM)、非酒精性脂肪肝(NAFLD)与血清胆碱酯酶(S-CHE)的关系。方法 随机选取221例T2DM患者,将患者分为T2DM合并NAFLD、未合并NAFLD两组。并随机选取同一时期体检的工人及退休人员206例,分为单纯NAFLD和正常对照组。所有被检者进行餐前和餐后2h血糖、糖化血红蛋白(HbA1c)、肝肾功能、血脂、S-CHE的检测以及肝胆胰脾B超检查;对T2DM患者进行空腹C肽和餐后C肽的测定,并计算胰岛素抵抗指数(HOMA2-IR)、胰岛素敏感度指数(HOMA2-%S)、胰岛β细胞功能(HOMA2-%B)。结果 DM合并NAFLD和单纯NAFLD组的S-CHE水平明显高于T2DM未合并NAFLD组和正常对照组(P均<0.01);随着T2DM病程的延长,S-CHE、ALT、GGT、TG、TC、空腹C肽、餐后C肽的水平逐渐下降,年龄逐渐增高(P<0.05或P<0.01);将T2DM患者分为A(S-CHE<8900IU/L)、B(S-CHE≥8900IU/L)两组,B组患者的BMI、脂肪肝百分比、ALT、AST、GGT、TG、TC、LDL-C、HOMA2-IR高于A组,HOMA2-%S低于A组(P<0.05或P<0.01);Pearson偏相关分析显示,校正年龄、性别、病程、HbA1c、FBG、收缩压、舒张压后,S-CHE与HOMA2-IR、BMI、TG、TC、LDL-C、ALT、GGT水平呈正相关,与HOMA2-%S呈负相关(P<0.05或P<0.01);多元线性回归分析显示,S-CHE与TC、HOMA2-IR、ALT水平呈正相关(R2=0.281,P均<0.01)。结论 S-CHE的水平在NAFLD患者明显增高,而未合并NAFLD的T2DM患者S-CHE的水平并无增高,S-CHE水平升高主要与脂肪肝、胰岛素抵抗及血脂紊乱相关,常规检测S-CHE可以反映T2DM患者胰岛素抵抗的情况以及早期预测NAFLD的发生。  相似文献   

3.
目的 探讨平均血小板体积等参数在急性胰腺炎病程中变化的临床意义及其对治疗效果评估的价值。方法 回顾性分析53例轻症急性胰腺炎(MAP)患者、25例重症急性胰腺炎(SAP)患者和40例健康者(对照组)的临床资料,检测平均血小板体积(MPV)、血小板计数(PLT)、血小板分布宽度(PDW)、白细胞计数(WBC)、C反应蛋白(CRP)及血清钙离子浓度(Ca2+)等指标。比较并分析上述指标在急性胰腺炎病程中及治疗前后的变化。结果 与对照组比较,急性胰腺炎患者入院时MPV显著升高,差异具有统计学意义(P<0.05);与MAP组比较,SAP组入院时MPV明显升高,差异具有统计学意义(P<0.05);SAP组中,MPV在入院后第3天较入院时进一步升高,至入院第5天、第7天逐渐下降;SAP组中,MPV在病程中各时间点与MAP组比较均显著升高,差异有统计学意义(P<0.05);与治疗前比较,急性胰腺炎患者治疗后MPV显著降低,差异有统计学意义(P<0.05)。结论 急性胰腺炎患者平均血小板体积与病情严重程度及治疗效果相关。  相似文献   

4.
目的 探讨铁过载对原代培养脐静脉内皮细胞(HUVECS)超氧化物歧化酶(SOD)、活性氧表达的影响及川芎嗪的干预效应。方法 使用酶联免疫法(ELISA)检测体外培养铁过载脐静脉内皮细胞表达的超氧化物歧化酶和活性氧的含量。结果 与空白组比较,模型组超氧化物歧化酶的含量显著降低(P<0.01),给药组超氧化物歧化酶与模型组比较,差异有统计学意义(P<0.05);模型组活性氧含量显著高于空白组(P<0.01),与模型组相比,给药组活性氧含量有明显降低(P<0.05)。结论 川芎嗪能抑制脐静脉内皮细胞铁过载导致的氧化应激,有通过抗氧化应激发挥抗动脉粥样硬化的作用。  相似文献   

5.
目的 探讨研究同型半胱氨酸(homocysteine,Hcy)水平与脑梗死患者亚甲基四氢叶酸还原酶(MTHFR)基因C677T的多态性之间的相关性。方法 选择2012年2月~2015年8月期间在笔者医院住院就诊的450例脑梗死患者作为研究组,其中糖尿病患者181例,非糖尿病患者269例,另外选择285例笔者医院门诊部健康的体检人员作为对照组,分别采用焦磷酸测序的方法检测分析MTHFR基因C677T的多态性,并分析各基因型与Hcy水平之间的相关性。结果 脑梗死组与健康对照组的MTHFR基因型分布之间的差异具有统计学意义(P<0.05),脑梗死组T基因的频率明显比对照组高,差异有统计学意义(χ2=13.67,P=0.00)。脑梗死组患者的Hcy浓度明显高于健康对照组,差异有统计学意义(t=12.71,P=0.00)。脑梗死组患者各MTHFR基因型患者的Hcy水平之间比较,差异有统计学意义(F=17.68,P=0.00)。非糖尿病脑梗死患者的Hcy水平明显高于糖尿病脑梗死患者,差异有统计学意义(t=2.97,P=0.00),非糖尿病组TT型的Hcy浓度明显高于糖尿病组,CC型的Hcy浓度明显低于糖尿病组,差异均有统计学意义(t=5.67,2.18;P=0.00,0.03)。糖尿病性脑梗死患者和非糖尿病脑梗死患者中,MTHFR基因为TT型的Hcy水平明显高于CC型和CT型,差异均有统计学意义(P<0.05),而CC型和CT型的Hcy水平之间比较差异无统计学意义(P>0.05)。结论 脑梗死患者比健康人的MTHFR基因C677T的T等位基因频率高,且脑梗死患者的MTHFR基因C677T为TT基因型时血清中Hcy的水平更高,由此判断TT基因型可能是脑梗死发生的危险因素。  相似文献   

6.
目的 探究持续封闭负压引流技术(VSD)对瘢痕切除创面成纤维细胞生长环境的影响。方法 回顾性分析2014年1月~2015年11月于笔者医院行植皮手术的四肢瘢痕切除术后患者60例,根据植皮手术前是否接受VSD治疗分为负压组(n=30)和包扎组(n=30),负压组均于一期植皮前接受VSD治疗,包扎组未接受VSD治疗。回顾性分析对比两组患者并发症发生率、首次植皮存活率、创面感染率、住院时间之间的差异。并用TUNEL染色、CD34染色法对比瘢痕标本中成纤维细胞凋亡指数及血管生成情况。结果 负压组菌培养阳性率明显低于包扎组(P<0.05),植皮存活率明显高于包扎组(P<0.05)。两组并发症发生率、住院时间、疼痛评分、随访VSS评分间比较,负压组均明显较低(P<0.05)。负压组成纤维细胞凋亡指数明显较低,微血管计数明显较高(P<0.05)。结论 负压封闭引流可以减轻瘢痕切除创面感染率,有效减轻炎性水肿,且可以通过改变局部血液循环微环境以及机械应力作用促进成纤维细胞增殖分裂,提高创面恢复效果。  相似文献   

7.
目的 探讨脓毒症患者中横纹肌溶解综合征(RM)与病情严重程度及预后的关系。方法 采用前瞻性研究方法,入选2014年10月~2015年9月重庆医科大学附属第一医院中心ICU连续收治的脓毒症患者151例作为研究对象。检测入ICU当天的血清肌酸激酶(CK),以CK≥1000U/L作为RM的诊断标准,比较发生RM的患者与未发生RM患者的感染标志物、危重症评分、器官功能障碍和28天病死率等。结果 151例脓毒症患者中37例(24.5%)发生RM。RM组的PCT水平、APACHEⅡ评分和SOFA评分较非RM组高(P<0.05)。RM组ICU期间肝脏功能障碍、循环障碍、肾脏功能障碍的发生率、人均器官障碍数、血肌酐峰值水平、接受连续肾脏替代治疗(CRRT)患者的比例和28天病死率较非RM组高(P<0.05),而呼吸功能障碍、凝血功能障碍和神经系统障碍的发生率比较,差异无统计学意义(P>0.05)。CK对预测脓毒症患者28天死亡风险具有统计学意义,ROC曲线下面积(AUC)为0.694(P<0.05),低于APACHEⅡ评分(0.841)和SOFA评分(0.805)(P<0.05)。结论 脓毒症患者中RM的发生率高,发生RM的患者的病情更危重,其ICU期间肝脏功能障碍、循环障碍、肾脏功能障碍的发生率和28天病死率均显著增加,CK可以作为预测脓毒症患者28天病死率的参考指标。  相似文献   

8.
目的 探讨甲状腺激素受体β1(thyroid hormone receptor β1,TRβ1)、β-链蛋白(β-catenin)及细胞周期蛋白A2(Cyclin A2)在甲状腺乳头状癌(thyroid papillary carcinoma,TPC)组织中的表达及意义。方法 应用免疫组化(SP)法分别检测30例正常甲状腺组织、30例结节性甲状腺肿伴乳头状增生(nodular goiter with papillary hyperplasia,NGWPH)及116例TPC组织中TRβ1、β-catenin及Cyclin A2的表达,同时检测肿瘤淋巴管密度(lymphtic vessel density,LVD),分析它们与临床病理指标的关系。结果 与正常甲状腺组织和NGWPH组织比较,TPC组织中TRβ1的表达阳性率降低,β-catenin在细胞膜表达显著减弱,而胞质表达明显增强,Cyclin A2的表达阳性率升高,差异有统计学意义(P<0.01)。相关性分析结果显示,TRβ1与β-catenin和Cyclin A2的表达呈负相关(r=-0.656和-0.525,均P<0.01),β-catenin和Cyclin A2呈正相关(r=0.384,P<0.01);淋巴结转移组的LVD显著高于无淋巴结转移组(P<0.05);TRβ1低表达、β-catenin胞质异常表达及Cyclin A2过表达与TPC包膜外侵、LVD及淋巴结转移有关(P<0.05),而与患者年龄、性别、组织类型、肿瘤直径、是否为多病灶无相关性(P>0.05)。结论 TRβ1通过使β-catenin在细胞内大量蓄积,继而诱导下游靶基因Cyclin A2表达途径参与TPC的发生和进展。  相似文献   

9.
陈燊  黄雯  张梅  张国娟 《寒旱区科学》2017,9(5):112-115
目的 探讨硫化氢(hydrogen sulfide,H2S)与糖尿病肾病(diabetic nephropathy,DN)大鼠肾细胞外基质过度积聚的关系。方法 21只SD大鼠随机分成正常对照组(对照组)、糖尿病肾病组(DN组)、硫化氢干预组(DN+H2S组)。链脲佐菌素(STZ)法建立糖尿病大鼠模型,DN+H2S组给予NaHS治疗8周,其他组给予同等剂量的0.9%生理盐水治疗。观察3组大鼠肾脏病理改变、BrdU阳性细胞和α平滑肌肌动蛋白(α-smooth muscle actin,α-SMA)分布差异。结果 与对照组比较,DN组大鼠尿蛋白量、相对肾重均明显增多,病理呈典型的DN改变,BrdU阳性细胞比值、肾小球α-SMA表达和分布显著增多(P<0.01);应用NaHS治疗后,大鼠肾脏DN改变明显减轻(P<0.01),BrdU阳性细胞比值、肾小球α-SMA表达和分布与正常对照组比较,差异无统计学意义(P>0.05)。结论 H2S可以抑制DN大鼠肌性成纤维细胞增殖,减少α-SMA表达和分布,减缓DN大鼠的肾小球细胞外基质积聚。  相似文献   

10.
目的 初步探讨P16INK4A联合HPV L1壳蛋白检测在宫颈鳞状上皮内病变诊断中的应用价值。方法 选择在温州市人民医院就诊患者,收集69例宫颈鳞状上皮内病变标本,行P16INK4A、HPV L1壳蛋白检测,分析P16INK4A、HPV L1壳蛋白及P16INK4A联合HPV L1壳蛋白在各级宫颈病变中的表达差异。结果 P16INK4A在LSIL组、HSIL组、SCC组中的阳性率分别为45.5%、85.2%、100.0%。同LSIL组比较,P16INK4A在HSIL组及SCC组阳性率明显升高(P<0.01)。HPV L1壳蛋白在LSIL组、HSIL组、SCC组中的阳性率分别为63.6%、18.5%、0%,HPV L1壳蛋白在LSIL组中阳性率明显低于HSIL组及SCC组(P<0.01)。随着宫颈病变加重,P16+/L1-阳性率有升高趋势(P<0.01),P16-/L1+阳性率有下降趋势(P<0.01)。LSIL组中P16+/L1-阳性率明显低于HSIL组和SCC组(P<0.01),SCC组P16+/L1-阳性率较HSIL组有明显提高(P<0.05)。LSIL组中P16-/L1+阳性率明显低于HSIL组和SCC组(P<0.01)。P16+/L1-较P16INK4、HPV L1壳蛋白单一检测筛查HSIL+特异性明显升高(P<0.01)。结论 P16INK4A联合HPV L1壳蛋白有望成为诊断宫颈鳞状上皮内病变的有效指标。  相似文献   

11.
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On Geography and Its History. D.R. Stoddart.

Transportation Networks: A Quantitative Approach. D. Teodorovic.

Processes in Physical Geography. R.D. Thompson, A.M. Mannion, C.W. Mitchell, M. Parry, J.R.G. Townshend.

Imaging Radar for Resources Surveys. J.W. Trevett.

Dominance and Affection: The Making of Pets. Yi-Fu Tuan.

Capturing the Horizon. The Historical Geography of Transportation since the Transportation Revolution of the Sixteenth Century. James E. Vance, Jr.

Nations at Risk: The Impact of the Computer Revolution. Edward Yourdon.  相似文献   

12.

Book Reviewed in this article:

Latin America: Case Studies. Richard G. Boehm and Sent Visser

Locality and Rurality: Economy and Society in Rural Regions. Tony Bradley And Philip Lowe

The City and the Grassroots. Manuel Castells

Geopolitics and Conflict in South America. Quarrels among Neighbors. Jack Child

Post-Industrial America: A Geographical Perspective. David Clark

Coastal Research: UK Perspectives. Malcolm W. Clark

A Rural Policy for the EEC? Hugh Clout

Peasant Agriculture in Assam: A Structural Analysis. M. M. Das.

Environmental Change and Tropical Geomorphology. I. Douglas and T. Spencer

Advances in Abandoned Settlement Analysis: Application to Prehistoric Anthrosols in Colombia, South America. Robert C. Eidt

Measuring Culture. Jonathan L. Gross and Steve Rayner

North America: A Human Geography. Paul Guinness and Michael Bradshaw

A Geographical Bibliography for American Libraries. Chauncy D. Harris et al.

Geography and the Urban Environment: Progress in Research and Applications, Vol. VI. D. T. Herbert and R. J. Johnston

Changes in Global Climate: A Study of the Effect of Radiation and Other Factors During the Present Century. K. Ya. Kondrat'ev.

Rural Development and the State: Contradictions and Dilemmas in Developing Countries. David A. M. Lea and D. P. Chaudhri

The Martial Metropolis: U.S. Cities in War and Peace. Roger W. Lotchin

The Climate of the Earth. Paul E. Lydolph.

Weather and Climate. Paul E. Lydolph.

Spatial Divisions of Labor: Social Structures and the Geography of Production. Doreen Massey.

Panorama of the Soviet Union. N. Mikhailov.

Soviet Armenia. K. S. Demirchian.

USSR: Geography of the Eleventh Five-Year Plan Period. K. Spidchenko.

Planung und Verwirklichung der Wiener Ringstrassenzone (Planning and Materialization of the Ringstrasse-Zone of Vienna). Kurt Mollik, Hermann Reining, Rudolf Wurzer.

The American West Transformed: The Impact of the Second World War Gerald D. Nash.

An Overview of the Survey of Income and Program Participation. Dawn Nelson, David McMillen, and Daniel Kasprzyk.

Phenomenology, Science and Geography: Spatiality and the Human Sciences. John Pickles.

Biological Diversification in the Tropics. Ghillean T. Prance

Die Wanderviehwirtschaft im gebirgigen Westen der U.S.A. und ihre Auswirkungen im Naturraum. Gisbert Rinschede.

Social and Economic Aspects of Radioactive Waste Disposal: Considerations for Institutional Management

World-Wide Weather. K. Takahashi

Coastal Geomorphology in Australia. B. G. Thom

Settlement System in Rural India: A Case Study of the Lower Ganga-Yamuna Doab. Ram Chandra Tiwari.

Computer Programming for Geographers. David J. Unwin and John A. Dawson.

Late Quaternary Environments of the Soviet Union. A. A. Velichko, ed. H. E. Wright, Jr. and C. W. Barnosky

Ethics in Planning. Martin Wachs  相似文献   

13.
Book Reviews     

Books reviewed in this article:

Aerial Photography and Remote Sensing Aerial photography and image interpretation for Resource Management. DAVIDP. PAINE.

Analytical Models and Techniques Spatial Processes Models and ApplicationsA. D. CLIFFAND J. K. ORD

Quantitative and Statistical Approaches to Geography: A Practical ManualJOHNA. MATTHEWS.

Cartography and Maps Map Data Processing. HERBERTFREEMANAND GOFFREDOG. PIERONI, eds.

Computer-assisted Cartography: Principles and Prospects, 1982. MARKS. MONMONIER.

Cultural Navajo Architecture: Forms, History, Distributions. STEPHENC. JETTAND VIRGINIAE . SPENCER.

Rational Landscapes and Humanistic Geography. EDWARDRELPH.

Economic The Structure and Control of a State Economy. W. L. L'ESPERANCE.

Economic Geography. JAMES O. WHEELER AND PETER O. MULLER.

The Myth of the Family Farm: Agribusiness Dominance of U.S. Agriculture. INGOLF VOCELER.

Libya: The Experience of Oil. J. A. ALLEN.

Geography of Public Finance, Welfare Under Fiscal Federalism and local Government Finance. ROBERT BENNETT.

Environmental Management, Resources, and Systems Mountains and Man. LARRY W. PRICE.

Environmental Geology. DONALD R. COATES.

An Introduction to Environmental Systems. G. H. DURY.

The Environment: Chinese and American Views. Edited by LAURENCE J. C. MAAND ALLEN G. NOBLE.

Land Use in America. RICHARD H. JACKSON.

Medical Conceptual and Methodological Issues in Medical Geography. MELINDA S. MEADE (ed.).

Philosophy and Geographic Thought Birds in Egg/Eggs in Bird. GUNNAR OLSSON.

PhysicaI Climatology: Selected Applications. J. E. OLIVER.

Geomorphological Techniques. ANDREW GOUDIE (ed.).

Political Politics, Geography and Behaviour. RICHARD MUIR AND RONAN PADDISON.

The State of the World Atlas. MICHAEL KIDRON AND RONALD SECAL.

Population The Population of the South. DUDLEY L. POSTON, JR. AND ROBERT H. WELLER, eds.

Regional Latin America: Economic Development and Regional Differentiation. ARTHUR MORRIS.

Developing the Amazon. EMILIO F. MORAN.

Western Europe: A Systematic Human Geography. BRIAN W. ILBERY.

Settlement Systems in Sparsely Settled Regions: The United States and Australia. RICHARD E. LONSDALEAND JOHN H. HOLMES, eds.

African Perspectives: The Economic Geography of Nine African States. HARMDEBUJAND ESMOND MARTIN, eds.

Rural Nonmetropolitan America in Transition. AMOS H. HAWLEYAND SARA MILLS MAZIE, eds.

Social Crime and Environment. R. NORMAN DAVIDSON.

The Ghetto: Readings with Interpretations. JOE T. DARDEN, ed.

Urban Urban Problems and Planning in the Developed World. MICHAEL PACIONE (ed.)

Problems and Planning in Third World Cities. Edited by MICHAEL PACIONE.

The City in West Europe. D. BURTENSHAW, M. BATEMAN, AND C. J. ASHWORTH.  相似文献   

14.

Reviews of geographic software in this article:

DEMO-GRAPHICS: WORLD POPULATIONS AND PROJECTIONS.

ESP

GAUSS.

CEMODEL S. Damus

LIMDEP. William H. Greene

MICROSTAT 4.1

OTIS

PCIPS. (Personal Computer Image Processing System). H.J. Meyers and R. Bernstein.

REGRESSION ANALYSIS OF TIME SERIES (RATS)

SPSS/PC+

URBAN DATA MANAGEMENT SOFTWARE (UDMS)  相似文献   

15.
Book Reviewed in this article:

Main Street: Northeastern Oregon: The Founding and Development of Small Towns. Barbara Ruth Bailey.

Food Politics: The Regional Conflict. David N. Balaam and Michael J. Carey, eds.

The International Economy and Industrial Development: Trade and Investment in the Third World. R. Ballance, J. Ansari and H. Singer.

Neighborhoods in Urban America. Ronald H. Bayor, ed.

The English Heartland. By Robert Beckinsale and Monica Beckinsale.

Regional Dimensions of Industrial Policy. Michael E. Bell and Paul S. Lande, eds.

Tension Areas of the World. D. Gordon Bennett, ed.

Latin America: an Introductory Survey. B. W. Blouet and O. M. Blouet, eds.

Integration and Division: Geographical Perspectives on the Northern Ireland Problem. Frederick W. Boal and J. Neville H. Douglas, eds.

Energy and Land Use. Robert W. Burchell and David Listokin, eds.

Slopes and Weathering. Michael Clarke and John Small.

Alaska's Rural Development. Peter G. Cornwall and Gerald McBeath, eds.

The Politics of Park Design: A History of Urban Parks in America. Galen Cranz.

World Congress on Land Policy, 1980, Proceedings. Matthew Cullen and Sharon Woolery, eds.

Oregon Divided: A Regional Geography. Samuel N. Dicken and Emily F. Dicken.

Urban Food Marketing and Third World Rural Development. T. Scarlett Epstein.

South Africa: Spatial Frameworks for Development. T. J. D. Fair.

Institutions and Geographical Patterns. Robin Flowerdew, ed.

Industrialization of U.S. Agriculture, An Interpretive Atlas. Howard F. Gregor.

Planning Theory: Prospects for the 1980s. Patsy Healy, Glen McDougall and Michael J. Thomas, eds.

Neighborhood Mobilization: Redevelopment and Response. Jeffrey R. Henig.

The American Urban System: A Geographical Perspective. R. J. Johnston.

Climate, History and the Modern World. Hubert H. Lamb.

Climate and History: Studies in Past Climates and Their Impact on Man. T. M. L. Wigley, M. J. Ingram and G. Farmer.

China: Railways and Agricultural Development, 1875–1935. Ernest P. Liang.

A Desirable Energy Future—A National Perspective. Robert S. Livingston, T. D. Anderson, T. M. Besmann, M. Olszewski, A. M. Perry, and C. D. West.

Topothesia: Essays Presented to T. S. Ó Máille. B. S. Mac Aodha, ed.

Transportation for the Poor: Research in Rural Mobility. Hal S. Maggied.

Land Uses in American Cities. Harold M. Mayer and Charles R. Haves.

Industrial Organisation and Location. Philip McDermott and Michael Taylor.

Human Adaptability: an Introduction to Ecological Anthropology. Emilio F. Moran.

Regional Analysis and the New International Division of Labor. Frank Moulaert and Patricia W. Salinas, eds.

The Nuclear War Atlas. Victoriaville, Quebec, Canada:

Urbanization and Environmental Quality. Isao Orishimo.

The Garden of Eden: The Botanic Garden and the Re-Creation of Paradise. John Prest.

Earthfire, The Eruption of Mount St. Helens. Charles Rosenfeld and Robert Cooke.

Contest for the South China Sea. Marwyn S. Samuels.

The Future of the Wetlands: Assessing Visual-Cultural Values. Richard C. Smardon, ed.

Tucson: the Life and Times of An American City. C. L. Sonnichsen.

The Geography of Multinationals. Michael Taylor and Nigel Thrift, eds.

Impact of Marine Pollution on Society. Virginia Tippie and Dana Kester.

Reviving the Industrial City: the Politics of Urban Renewal in Lyon and Birmingham. Jerry A. Webman.

Andean Reflections: Letters from Carl O. Sauer While on a South American Trip under a Grant from the Rockefeller Foundation, 1942. Robert C. West, ed.

Cartographic Drawing with Computers. P. Yoeli.  相似文献   

16.
《The Journal of geography》2012,111(6):290-300
Abstract

Ralph and Mollie Izzard. A Walk in the Mountains, A Family's Trip Through the High Lebanon.

Wesley Calef. Private Grazing and Public Lands, Studies of the Local Management of the Taylor Grazing Act.

S. H. Steinberg (editor). The Statesman's Yearbook, 1960-1961.

E. Joseph Dreany. Alaska.

John C. and Elsie F. Caldwell. Our Neighbors in Japan.

R. J. Harrison Church. West Africa: A Study of the Environment and of Man's Use of it.

Alex Somme, editor. A Geography of Norden.  相似文献   

17.

Geographic Software Reviewed in this article:

LIFE TABLES and the LESLIE MATRIX. CONDUIT

MENTMAP2. Lawrence W. Carstensen Jr.

PC-MATLAB, Version 1.0. The Math Works, Inc.

QUICKMAP, version 1.0. Sammamish Data Systems, Inc.

SYSTAT: THE SYSTEM FOR STATISTICS, Version 2.1, Systat Inc.

USA DISPLAY. Instant Tecall  相似文献   

18.

Geographic Software Reviewed in this article:

APPLEPIPS

IBM EDUCATIONAL SOFTWARE SERIES: EARTH SCIENCE SERIES. Moisture in the Atmosphere, Hydrologic Cycle, Surface Water Ground Water

MINI-MAX

MULTIMAP. Barry R. Cohen. Planning Data Systems

WORLD GEOGRAPHY SERIES, U.S. GEOGRAPHY QUIZ, U.S. GEOGRAPHY ADVENTURE  相似文献   

19.
Electromap World Atlas, Version 1.1.

Interactive Population Statistical System, Version 1.0. Jerry W. Wicks and Jose Luiz Pereira de Almeida

MATHCAD, Version 2.5.

Memory Mate.

Micro DEM+, Version 5.21. Peter Guth

NCSS – Number Cruncher Statistical System, Version 5.02. Dr. Jerry L. Hintze  相似文献   

20.
ATLAS?GRAPHICS (Version 3.0).

AutoCAD (Release 9.0 with ADE+1, ADE+2 and ADE+3).

AutoSketch (Speed Enhanced Version 1.02).

NUMERICAL RECIPES FORTRAN. Numerical Recipes Software

SCIPLOT.  相似文献   

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