PM_2.5降尘对A549细胞线粒体氧化损伤的影响     

宋小芳  杨洁  霍婷婷  马骥  董发勤  马杰  王玉琳  邓建军 《岩石矿物学杂志》2018,37(6):985-992

将不同浓度PM_(2.5)降尘作用于A549细胞后,利用MTT法检测其存活率,W-G染色观察细胞形态,荧光探针法检测细胞ROS和MMP相对水平,以探讨PM_(2.5)降尘对A549细胞线粒体氧化损伤的影响及作用机制。结果显示,经12. 5μg/m L的PM_(2.5)降尘作用A549细胞3 h后,细胞存活率为(81. 77±6. 15)%,并随作用浓度及时间增加呈递减趋势。PM_(2.5)染毒后可观察到细胞形态不规则,胞膜溶解破坏,细胞微核出现。PM_(2.5)降尘作用于细胞24 h后,胞内ROS相对含量随暴露浓度增加呈递增趋势,细胞MMP相对水平随染毒浓度增加而降低,且胞内ROS和MMP两者间存在显著相关关系(R2=0. 878)。提示PM_(2.5)降尘处理A549细胞后可通过刺激ROS的产生,诱导细胞MMP下降,造成细胞线粒体氧化损伤。  相似文献   

A non-hydrostatic model for the numerical study of landslide-generated waves     

Pengfei Si  Jordan Aaron  Scott McDougall  Ji Lu  Xiping Yu  Nicholas J. Roberts  John J. Clague 《Landslides》2018,15(4):711-726

This paper proposes and demonstrates a two-layer depth-averaged model with non-hydrostatic pressure correction to simulate landslide-generated waves. Landslide (lower layer) and water (upper layer) motions are governed by the general shallow water equations derived from mass and momentum conservation laws. The landslide motion and wave generation/propagation are separately formulated, but they form a coupled system. Our model combines some features of the landslide analysis model DAN3D and the tsunami analysis model COMCOT and adds a non-hydrostatic pressure correction. We use the new model to simulate a 2007 rock avalanche-generated wave event at Chehalis Lake, British Columbia, Canada. The model results match both the observed distribution of the rock avalanche deposit in the lake and the wave run-up trimline along the shoreline. Sensitivity analyses demonstrate the importance of accounting for the non-hydrostatic dynamic pressure at the landslide-water interface, as well as the influence of the internal strength of the landslide on the size of the generated waves. Finally, we compare the numerical results of landslide-generated waves simulated with frictional and Voellmy rheologies. Similar maximum wave run-ups can be obtained using the two different rheologies, but the frictional model better reproduces the known limit of the rock avalanche deposit and is thus considered to yield the best overall results in this particular case.  相似文献   

A direction-dependent shear strength criterion for rock joints with two new roughness parameters     

Liren Ban  Chengzhi Qi  Chunsheng Lu 《Arabian Journal of Geosciences》2018,11(16):466

The surface morphology of a rock joint is closely related to its mechanical properties. To reasonably characterize a rock surface, two new roughness parameters were proposed in this paper. One is related to the average slope angle of asperities that contribute to the shear strength, and the other reflects the frictional behavior of asperities that is defined as the maximum possible contact area in the shear direction. Taking the standard joint roughness coefficient profiles as example, these two roughness parameters can be applied to describe the directional characteristics of shear strength. Based on their relationships with initial dilation angles, the proposed roughness parameters were incorporated into a peak shear strength criterion. It is shown that the predicted peak shear strength is consistent with experimental data, and there is a power–law relationship. The application range of new roughness parameters was determined, which may facilitate a measurement process.  相似文献   

Zircon U–Pb–Hf isotopes and geochemistry analyses of the Huyu igneous rocks in northwestern Beijing,China: possible new evidence for the initial destruction of the North China Craton     

Zejia Ji  Baofu Han  Haifei Yu  Yan Chen 《International Geology Review》2018,60(2):196-216

The timing and extent of cratonic destruction are crucial to understanding the crustal evolution of the North China Craton (NCC). Zircon U–Pb–Hf isotope data and the whole-rock major and trace element characteristics of the Huyu igneous rocks in northwestern Beijing, China, provide possible new evidence for the initial destruction of the NCC. The igneous rocks occur as several sills and dikes, including lamprophyre, monzonite porphyry, and aplite. The lamprophyres have high Mg^# and K₂O contents. The monzonite porphyries have high Mg^#, high K₂O contents, and negative ε_Hf(t) values with zircon U–Pb ages of 225.5–227.7 Ma. These two types of rocks are both enriched in large ion lithosphere elements (LILEs) and light rare earth elements (LREEs) but are depleted in high field strength elements (HFSEs) and high rare earth elements (HREEs) and have almost no Eu anomalies and relatively high total rare earth element (ΣREE) contents. In contrast, the aplites exhibit high silica and K₂O contents, low MgO contents, and more negative ε_Hf(t) values with a zircon U–Pb age of 206.2 Ma. The aplites are also enriched in LILEs and LREEs but are depleted in HFSEs and HREEs, with strongly negative Eu, Ti, P, La, Ce, and Sr anomalies and relatively low ΣREE contents. These results indicate that the lamprophyres and monzonite porphyries represent a continuous cogenetic magma evolution series after melt derived from an enriched metasomatized lithospheric mantle experienced crust assimilation and fractional crystallization. The aplites were produced by the fractional crystallization of low-Mg parental magma derived from melting of the ancient Archaean crust. The occurrence of the Huyu intrusive rocks with many other plutons of similar ages on the northern margin of the NCC suggests that the northern NCC entered an intraplate extensional tectonic environment in the Late Triassic.  相似文献   

大数据环境下内蒙古浩布高地区铅锌多金属矿智能矿产预测研究          下载免费PDF全文

季 斌周涛发  张达玉李晓晖 袁 峰 《地质科学》2018,(4):1347-1360

传统机器学习算法已广泛应用于矿产预测,但面对地质大数据的高维稀疏、不平衡小样本等特性仍缺乏有效处理和分析的方法,设计适合地质大数据特点的机器学习算法是智能矿产预测亟需解决的新问题。本文以内蒙古浩布高地区的铅锌多金属矿产预测为例,提出了一种面向地质大数据的半监督协同训练矿产预测模型。首先对研究区地质找矿信息和地球化学异常信息进行定量分析,提取断裂构造、二叠系地层、燕山期侵入岩、地层与岩体接触带、围岩蚀变及Pb、Zn、Sn、Cu地球化学异常共9种找矿因子。然后利用递归特征消除法优选找矿因子组合,不包括Sn异常在内的8个找矿因子组合被选为最优组合。最后,利用支持向量机和随机森林算法作为基分类器进行半监督协同训练矿产预测,绘制成矿概率分布图。ROC曲线和预测度曲线分析结果表明,半监督协同训练模型的AUC值和预测效率都高于随机森林和支持向量机模型。研究结果也为大数据环境下的智能矿产预测提供了一种新的思路。  相似文献   

地球接受太阳辐射能量变化对板块构造影响的估算          下载免费PDF全文

田嘉铖  季建清 《地质科学》2018,(4):1499-1512

板块构造理论可以被认为是构造地质学研究的基本模型和框架。传统板块构造理论认为岩石圈板块在软流圈上方随软流圈对流发生运动,软流圈对流所需要的能量则完全由地球内部能量,如重力势能和放射性衰变产生的热能提供。但是近年来的一些研究证明了气候变化会对板块构造活动,如造山带活动产生直接影响。对传统的板块构造所需能量全部由地球内部提供这一观点做出了补充和更新。本文主要从两个方面对外动力作用可能影响板块构造做出分析,一是利用傅里叶分析证明了太阳辐射变化在构造活动,如洋中脊两侧地貌和火山沉积物中均能够留下记录;二是建立了一个简单的平面力学模型,探究洋流同大陆的力学作用会如何影响大陆运动特征。虽然这一模型忽略了很多因素,定量计算的结果本身并不具有很严格的数据绝对意义。但是这一模型的结果可以证明地球所有板块构造活动中释放的能量低于地球系统每年从太阳辐射中接收的能量,而且模型得到的大陆运动特征同现今实际观测下的运动特征存在一致性,洋流向大陆岩石圈传递的能量同地震活动释放的能量处于同一量级,从侧面可以证明洋流可能对板块构造产生了较大的影响。  相似文献   

准噶尔盆地吉木萨尔凹陷梧桐沟组层序地层划分     

郭佳  宋双  王一博 《江苏地质》2018,42(4):558-567

准噶尔盆地吉木萨尔凹陷二叠系梧桐沟组作为一套重要的储集岩,具有良好的油气成藏前景,但对其层序划分及地层沉积样式的认识一直存在争议。在构造背景分析的基础上,结合岩芯、测井及地震资料,对研究区梧桐沟组层序地层划分及地层沉积样式研究表明,梧桐沟组沉积时期构造强度较弱,地形较为平缓,地层在全区稳定分布;中晚二叠世盆地发生造山运动,吉木萨尔凹陷东南边缘区域经过构造抬升,上部地层遭受不同程度的剥蚀,形成了现今"底平顶削"的地层样式。以凹陷中部少数地层保存较全的井的地层叠加样式分析为基础,通过井-震结合识别不同类型界面,特别是最大湖泛面,建立了区域层序地层格架,即梧桐沟组为一个完整的长期基准面旋回(三级层序),并在其内部识别出5个中期旋回。梧桐沟组地层在不同的层序发育时期表现出不同的旋回叠加样式:下段沉积时期,即最大湖泛面以下,随着可容纳空间的增大,地层表现为明显的退积叠加样式;上段沉积时期,即最大湖泛面以上,随着可容纳空间的减小,地层表现为明显的进积叠加样式,符合沉积物体积分配原理。  相似文献   

A noise suppression method for superconducting full tensor aeromagnetic gradient measurement data     

ZiQi Guo  ShuangXi Ji  Yanchao Qiao  Ji Wang 《《地质学报》英文版》2018,92(Z1):367-368

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A new evil waveforms evaluating method for new BDS navigation signals     

Chengyan He  Ji Guo  Xiaochun Lu  Xue Wang  Yongnan Rao  Li Kang  Zhigang Hu 《GPS Solutions》2018,22(2):37

With the advent of new global navigation satellite systems (GNSSs) and new signals, GNSS users will rely more on them to obtain higher-accuracy positioning. Evil waveform monitoring and assessment are of great importance for GNSS to achieve its positioning, velocity, and timing service with high accuracy. However, the advent of new navigation signals introduces the necessity to extend the traditional analyzing techniques already accepted for binary phase-shift keying modulation to new techniques. First, the well-known second-order step thread model adopted by the International Civil Aviation Organization is introduced. Then the extended new general thread models are developed for the new binary offset carrier modulated signals. However, no research has been done on navigation signal waveform symmetry yet. Simulation results showed that, waveform asymmetry may also cause tracking errors, range biases, and position errors in GNSS receivers. It is thus imperative that the asymmetry be quantified to enable the design of appropriate error budgets and mitigation strategies for various application fields. A novel evil waveform analysis method, called waveform rising and falling edge symmetry (WRaFES) method, is proposed. Based on this WRaFES method, the correlation metrics are provided to detect asymmetric correlation peaks distorted by received signal asymmetry. Then the statistical properties of the proposed methods are analyzed, and a proper deformation detection threshold is calculated. Finally, both simulation results and experimentally measured results of Beidou navigation satellite system (BDS) M1-S B1Cd signal are given, which show the effectiveness and robustness of the proposed thread models.  相似文献   

北羌塘地块上石炭统瓦垄山组的珊瑚化石     

张少文  李涌溪  武桂春  纪占胜 《地质论评》2021,67(Z1):67z1249-67z1250

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