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121.
The pharmacokinetic profiles and sulfamethoxazole (SMX) acetylation process in turbot reared at 18°C were investigated. Either SMX (parent drug) or its acetylized metabolite, N4-acetylsulfamethoxazole (AcSMX), was administered intravascularly to turbot at a dosage of 50 mg/kg BW. Serum concentrations of the parent drug and its metabolite were both measured by HPLC, and the changes in concentration over time were analyzed in two- and non-compartment models because SMX treatment produced multiple peaks. The results demonstrated that the elimination half-life of the parent drugs, SMX and AcSMX, were 159.2 and 5.9 h, respectively. The apparent volume of distribution was 0.2 and 0.8 L/kg, and the clearance was 0.038 and 0.222 L/(h·kg), for SMX and AcSMX, respectively. SMX acetylation in turbot was 2.8%, and the deacetylation of AcSMX was 0.2%. These findings may be useful in optimizing SMX dosage regimens in turbot aquaculture. 相似文献
122.
N. P. Safina N. R. Ayupova E. V. Belogub V. V. Maslennikov I. A. Blinov I. G. Zhukov D. A. Artem’ev 《Doklady Earth Sciences》2018,480(2):746-749
Gallium-containing chlorite, mica, and magnetite (up to 14, 13, and 5–7 wt % of Ga) along with Ga hydroxides (oxyhydroxides?) were found for the first time in massive sulfide deposit in the Urals. The minerals identified within the cement of chalcopyrite–sphalerite breccias of the Shemur copper–zinc–massive sulfide deposit (Northern Urals) are associated with Ga-enriched sphalerite, chalcopyrite, and, less commonly, pyrite (33–364, 67–363, and 4–230 g/t, respectively). 相似文献
123.
Analysis of gentle, intermediate, and steep dip angles of fault planes in earthquake sources of the Baikal region is carried out with the slips in seismic sources being taken into account. The areas where normal faulting slips at steep, intermediate, and gentle angles took place are distinguished, and this can be interpreted as transformation of a steep dip to gentle one. It is found that the increase in energy class is accompanied by the number of earthquakes with steep dip angles, whereas the proportion of earthquakes with intermediate angles decreases, and the fraction of earthquakes with gentle angles remains quasi-stable and small. 相似文献
124.
V. Yu. Kuznetsov E. V. Tabuns G. A. Cherkashev V. E. Bel’tenev F. E. Maksimov K. A. Kuksa L. I. Lazareva S. B. Levchenkoa I. E. Zherebtsov 《Doklady Earth Sciences》2018,478(1):26-30
The results of 230Th/U dating and mineralogical–geochemical studies of sulfide ores from the Irinovskoe hydrothermal field and the Severo-Zapadnoe ore occurrence (Mid-Atlantic Ridge) are presented. Sulfides are represented primarily by copper–sulfide ores with 12–30% Cu content; sulfur- and zinc-sulfide ores are distributed less frequently. The analysis of a change in the composition of sulfides over time has made it possible to identify three stages of formation. Each stage assumes that mineral associations are changed from high-temperature (sulfur and copper sulfide) to medium temperature (Zn–Cu and Zn-sulfide) sulfide ores. The whole age range of formation of the hydrothermal deposits falls within the time interval of about 58000–8000 for the Irinovskoe field and 69000–11000 years ago for the Severo-Zapadnoe ore occurrence. 相似文献
125.
A.?G.?SokolEmail author I.?N.?Kupriyanov A.?A.?Tomilenko T.?A.?Bul’bak Yu.?N.?Palyanov N.?V.?Sobolev 《Doklady Earth Sciences》2018,483(1):1451-1453
The main trends of water dissolution in Fe-bearing olivine have been investigated in the olivine–H2O–hydrocarbon fluid system in experiments at a pressure of 6.3 GPa, a temperature of 1200°C, and hydrogen fugacity ( fH2) buffered by the Mo–MoO2 equilibrium. The content and contribution of ОH defects of different types in Fe-bearing olivines depend on the composition of reduced fluids in the system. As the fraction of hydrocarbons in the fluid increases, the H2O content in olivine crystals decreases from 900 to 160–180 ppm, while the ОН absorption peaks become lower at high frequencies and occupy a larger part of the infrared spectrum in the low-frequency region. According to the experimental results, even the deepest seated mantle olivines with OH defects were not equilibrated with a fluid rich in light alkanes or oxygenated hydrocarbons. 相似文献
126.
Doklady Earth Sciences - For the Permian–Triassic foidite and meimechite lavas of Polar Siberia, both the whole-rock petrochemistry and geochemistry and that of melt inclusions in olivine... 相似文献
127.
The Stress–Strain State of Recent Structures in the Northeastern Sector of the Russian Arctic Region
Doklady Earth Sciences - Complex research to determine the stress–strain state of the Earth’s crust and the types of seismotectonic destruction for the northeastern sector of the... 相似文献
128.
V. L. Afanas’ev M. Yu. Piotrovich Yu. N. Gnedin S. D. Buliga T. M. Natsvlishvili 《Astronomy Reports》2018,62(2):138-143
The results of spectropolarimetric observations of a number of magnetic white dwarfs obtained on the 6-m optical telescope of the Special Astrophysical Observatory are presented. The observations were carried out using the SCORPIO focal aperture-ratio reducer in a spectropolarimetric regime. Two characteristic dependences of the degree of polarization on the wavelength are observed. For one group of objects, the degree of linear polarization grows with wavelength, suggesting that the alignment of atoms and molecules in Rydberg states in the atmosphere of the white dwarf due to the action of its magnetic field influences scattering processes. The second group of objects displays an increase in the degrees of both linear and circular polarization with wavelength, providing evidence for the presence of protoplanetary disks around these magnetic white dwarfs, in which the alignment of circumstellar grains leads to the observed behavior. 相似文献
129.
E.V. Deev I.D. Zol’nikov I.V. Turova G.G. Rusanov Yu.M. Ryapolova N.N. Nevedrova S.A. Kotler 《Russian Geology and Geophysics》2018,59(4):351-362
Paleoseismological studies confirm that the Uimon basin is thrust by its northern mountain border along the active South Terekta fault. The latest motion along the fault in the 7-8th centuries AD induced an earthquake with a magnitude of Mw= 7.4-7.7 and a shaking intensity of I = 9-11 on the MSK-64 scale. The same fault generated another event (M > 7, I = 9-10), possibly, about 16 kyr ago, which triggered gravity sliding. The rockslide dammed the Uimon valley and produced a lake, where lacustrine deposition began about 14 ± 1 kyr ago, and a later M > 7 (I = 9-10) earthquake at ~ 6 ka caused the dam collapse and the lake drainage. Traces of much older earthquakes that occurred within the Uimon basin are detectable from secondary deformation structures (seismites) in soft sediments deposited during the drainage of a Late Pleistocene ice-dammed lake between 100 and 90 ka and in ~ 77 ka alluvium. The magnitude and intensity of these paleoearthquakes were at least M > 5.0-5.5 and I > 6-7. 相似文献
130.
N. G. Lyubimtseva N. S. Bortnikov S. E. Borisovsky V. Yu. Prokofiev O. V. Vikent’eva 《Geology of Ore Deposits》2018,60(2):93-120
The mineral assemblages, mode of occurrence, and chemical compositions of coexisting fahlore and sphalerite from the Darasun gold deposit have been described. Three generations of fahlore and three generations of sphalerite have been recognized. The FeS content in sphalerite coexisting with fahlore ranges from 0.8 to 9.4 mol %. The complete solid solution series Fe-tetrahedrite–Zn-tetrahedrite–Fe-tennantite–Zn-tennantite reflected in Sb/(Sb + As) and Fe/(Fe + Zn) ratios ranging from 0 to 0.97 and from 0.07 to 1.00, respectively, with a predominant negative relationship between these ratios has been identified for the first time at the deposit. Stepped, oscillatory, and combined stepped-oscillatory growth zonings within fahlore grains and heterogeneous aggregates of fahlore have been found. Fahlore is enriched in As with respect to Sb, and Zn-tetrahedrite is followed by Fe- and Zn-tennantite from early to late generation; Zn-tetrahedrite is followed by Fe-tennantite in zoned grains and overgrown rims; sphalerite crystallized at decreased temperature and sulfur fugacity. The evolution of the chemical composition of fahlores was caused by the evolving temperature, fluid salinity, and conditions of metal migration. 相似文献