基于数据挖掘分析中药复方治疗肺癌伴恶性胸腔积液的用药规律          下载免费PDF全文

关鹏  沈云博  刘枫 《应用海洋学学报》2022,38(10):34

目的：运用中医传承计算平台（V3.0）分析中医药治疗肺癌伴恶性胸腔积液的用药规律。方法：计算机检索2000年1月1日至2022年2月28日中国知网（CNKI）、万方数据（WANFANG DATA）、维普中文科技期刊数据库（VIP）中关于中药复方治疗肺癌伴恶性胸腔积液的文献,分析中药的性味归经、功效、频次、药物组合、关联规则及聚类等。结果：共纳入文献98篇,处方103首,中药197味。频次≥20次的中药有18味,排前10位的依次为葶苈子、茯苓、白术、黄芪、大枣、甘草、泽泻、桂枝、半夏、薏苡仁。四气以寒、温、平为主;五味以甘、苦、辛为主;归经以肺、脾、胃经为主。排前3位的功效依次为补虚、利水渗湿、化痰止咳平喘。用药频次≥20次的中药组合有37组,排前4位的依次为茯苓-葶苈子、白术-茯苓、茯苓-黄芪、大枣-葶苈子。支持度≥25%的核心药物为黄芪、白术、茯苓、甘草、葶苈子、大枣、桂枝、泽泻。中药聚类分析提取到4个核心组合。结论：肺癌伴恶性胸腔积液多属晚期,以气血阴阳俱虚为本,饮停胸胁为标,病机多虚实夹杂。中医药治疗此病多以甘温益气补虚治本,苦寒泻肺利水治标,同时兼以温阳化气。  相似文献   

极浅海域波浪滑翔器跨介质通信实验          下载免费PDF全文

杨义军  姚俊辉  陈东升  童峰  兰维瑶 《数字海洋与水下攻防》2022,5(4):307-312

面向海洋立体信息感知中长期环境监测、目标探测、区域预警、跨介质信息中继等领域对极浅海域空海信息链路的需求,考虑极浅海域信道恶劣、潮流复杂、环境噪声严重等困难,采用直接序列扩频结合差分二进制相移键控(DS-DBPSK)的水声调制解调技术,以波浪滑翔器为平台进行水声通信、无线系统设计与整合,构建面向极浅海域水下信息支持的波浪滑翔机跨介质通信链路,并在平均深度 12 m 的厦门港海域开展极浅海域跨介质通信实验,验证了所设计技术方案及系统的有效性。  相似文献   

Complex adaptive blended learning for higher GIS education: A theory-driven pedagogy moving forward after the pandemic     

Yingwei Yan  Chen-Chieh Feng  Lewis Kwek Boon Leong 《Transactions in GIS》2023,27(5):1479-1502

None of the prior studies implementing blended learning (BL) for GIS education has explored pedagogical theories to support BL design, and none coupled blended GIS learning practice with theories. Based on the theoretical framework of complex adaptive blended learning system (CABLS), this article presents a holistic and systematic view of BL for higher GIS education (termed as CABLS-GIS), where its key components are tightly integrated as an integral whole. The framework was implemented for an introductory-level GIS course to empirically evaluate the effectiveness of a BL design from students' perspectives. Most students involved in the implementation agreed that the BL enhanced their learning outcomes. They were mostly positive about the BL and motivated to use the BL materials. Incorporating more BL materials, especially practical ones, and active learning activities were suggested by them. A few negative comments about the BL suggested a thorough consideration of individual learners' characteristics.  相似文献   

Climate Change Adaptation in Southeast Asia. Joy Jacqueline Pereira,Mohd Khairul Zain and Rajib Shaw  (eds). Springer Nature Singapore Pte Ltd,Singapore, 2021, pp. xv + 233. ISBN 978-9-811-66087-0 (hbk).     

Feng Kong 《Singapore journal of tropical geography》2023,44(3):563-566

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黄山风景区旅游废弃物生态足迹历时性分析     

施青雨  章锦河  孙枫  王亚如 《世界地理研究》2023,32(1):150-161

历时性旅游废弃物演化规律及生态影响研究是制定旅游地可持续发展战略的基础性工作。以生态足迹理论为基础,利用1979—2018年相关统计资料与团队实地调研数据,对黄山风景区旅游废弃物生态足迹的长时间序列动态变化进行特征研究。结果表明（：1）黄山风景区旅游废弃物生态足迹演变具有明显的阶段性特征,共分为1979—1987年持续上升、1988—1996年小范围浮动式下降、1997—2005年剧烈振荡以及2006—2018年趋于稳定四个阶段。（2）黄山风景区旅游废弃物生态足迹的来源及构成占比随着当地垃圾处理方式及污染防治措施的变化而变化。其中,固体垃圾的足迹占比最多且达到52.18%～97.99%,并从显性与隐性两方面对当地生态环境产生影响。（3）随着黄山风景区旅游经济增长,区域资源利用效益持续升高,环境质量稳定改善,始终处于可持续发展状态。（4）黄山风景区的实践表明成熟的环境管理体制和不断改进的卫生治理措施可将旅游废弃物造成的生态影响控制在一定范围之内,从而为其他山岳型景区可持续发展提供有益参考。  相似文献   

Transcriptome profile of Dunaliella salina in Yuncheng Salt Lake reveals salt-stress-related genes under different salinity stresses     

Gao  Fan  Nan  Fangru  Feng  Jia  Lü  Junping  Liu  Qi  Liu  Xudong  Xie  Shulian 《中国海洋湖沼学报》2021,39(6):2336-2362

Journal of Oceanology and Limnology - Salt stress is an abiotic stress to plants in especially saline lakes. Dunaliella, a halophilic microalga distributed throughout salt lakes and seas, can...  相似文献   

MamZ protein plays an essential role in magnetosome maturation process of Magnetospirillum gryphiswaldense MSR-1     

Wu  Sha  Wang  Qing  Wang  Xu  Guo  Ruixue  Zhang  Tongwei  Pan  Yongxin  Li  Feng  Li  Ying 《中国海洋湖沼学报》2021,39(6):2082-2096

Journal of Oceanology and Limnology - Based on analysis of gene structure of mamXY operon in Magnetospirillum gryphiswaldense strain MSR-1, we constructed a mamZ deletion mutant strain (ΔmamZ)...  相似文献   

基于ALBERT模型的园林植物知识实体与关系抽取方法     

陈晓玲  唐丽玉  胡颖  江锋  彭巍  冯先超 《地球信息科学学报》2021,23(7):1208-1220

园林植物知识图谱可为顾及区域适应性、观赏性和生态性等因子的绿化树种的选型提供知识支持。植物描述文本的实体识别及关系抽取是知识图谱构建的关键环节。针对植物领域未有公开的标注数据集,本文阐述了园林植物数据集的构建流程,定义了园林植物的概念体系结构,完成了园林植物语料库的构建。针对现有Word2vec、ELMo和BERT等语言模型存在无法解决多义词、融合上下文能力差、运行速度慢等缺点,提出了嵌入ALBERT（A Lite BERT）预训练语言模型的实体识别和关系抽取模型。ALBERT预训练的动态词向量能够有效地表示文本特征,将其分别输入到BiGRU-CRF命名实体识别模型和BiGRU-Attention关系抽取模型中进行训练,进一步提升实体识别和关系抽取的效果。在园林植物语料库上进行方法的有效性验证,结果表明ALBERT-BiGRU-CRF命名实体识别模型的F₁值为0.9517,ALBERT-BiGRU-Attention关系抽取模型的F₁值为0.9161,相较于经典的语言模型（如Word2vec、ELMo和BERT等）性能有较为显著的提升。因此基于ALBERT模型的实体与关系抽取任务能有效提高识别分类效果,可将其应用于植物描述文本的实体关系抽取任务中,为园林植物知识图谱自动构建提供方法。  相似文献   

Numerieal prediction of storm surge in the Qingdao area under the impact of climate change     

Jianlong Feng  Wensheng Jiang  Changwei Bian 《中国海洋大学学报(英文版)》2014,13(4):539-551

A typhoon-induced storm surge simulation system was developed for the Qingdao area, including a typhoon diagnostic model for the generation of wind and pressure fields and a 2D Advanced Circulation (ADCIRC) model for simulating the associated storm surge with a 200 m resolution along the Qingdao coastline. The system was validated by an extreme surge event Typhoon Mamie (8509) and the parameters of Typhoon Mamie were used to investigate the sensitivity of typhoon paths to Qingdao storm surges with four selected paths: the paths of Typhoons Mamie (8509), Opal, 3921 and 2413, the selection being made according to their relative position to Qingdao. Experiments based on the Typhoon Mamie (8509) storm surge were also conducted to study the possible influences of future climate changes, including the sea level rise and sea surface temperature (SST) rise, on storm surges along the Qingdao coast. Storm surge conditions under both present day and future (the end of the 21st century) climate scenarios associated with the four selected paths were simulated. The results show that with the same intensity, when typhoons follow the paths of 3921 and 2413, they would lead to the most serious disasters in different areas of Qingdao. Sea level and SST affect storm surges in different ways: sea level rise affects storm surge mainly through its influence on the tide amplitude, while the increased SST has direct impact on the intensity of the surges. The possible maximum risk of storm surges in 2100 in the Qingdao area caused by typhoons like Mamie (8509) was also estimated in this study.  相似文献   

云南剑川地区象鼻洞遗址孢粉组合和古环境   总被引：1，自引：0，他引：1  

张继效  王伟铭  高峰 《地球科学与环境学报》2014,(4)

为了解云南剑川旧石器时代中晚期植被和气候变化特点以及当地环境与人类活动的关系,选取象鼻洞遗址各地层的13个土样进行孢粉分析。结果表明:该遗址堆积时期孢粉植物群以亚热带和温带成分为主,类型相对丰富,呈温暖期气候特征,但气候存在小的波动,呈现出早期温暖湿润、中期短暂干旱、晚期又逐渐暖湿的特点;木本植物花粉在孢粉总量中占绝对优势,说明当时人类活动对自然环境的影响不明显;可作为食物来源的植物很少,因此,当时居住在象鼻洞的人类主要食物应来源于捕捞或狩猎;对照邻近地区已有的研究成果,推测该遗址气候变化与季风活动有关。  相似文献