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991.
1 IntroductionItisnowwellacceptedthemagneticfieldinfilamentisnearlyhorizontalandthecomponentofthefieldalongthefilamentaxisisdominant (D啨moulin ,1 997) .Whenafilamentispresentinactiveregion ,thephotospherictransversefieldbeneathfilamentmostlyliealongthepolar… 相似文献
992.
目的:探讨降气平喘方含药血清对哮喘大鼠气道平滑肌细胞(ASMC)中易感基因解整合素金属蛋白酶 33(ADAM33)和E26 转录因子-1(ETS-1)表达的影响及其作用机制。方法:通过卵清蛋白(OVA)致敏建立大鼠哮喘模型,另取SD雌性大鼠分组(降气平喘方组、孟鲁司特钠组)灌胃给药制备不同浓度的含药血清,即降气平喘方组血清分别配制为浓度5%、10%、15%的中药含药血清培养液,孟鲁司特钠组血清配制为30%浓度的西药含药血清培养液,分别对体外培养的ASMC进行同化干预24h。采用CCK8法测定不同含药血清对ASMC生长的抑制率,ELISA法检测各组细胞培养上清液中转化生长因子-β1(TGF-β1)、白细胞介素-6(IL-6)的浓度,Western Blot法检测各组细胞中ADAM33、ETS-1蛋白表达情况。结果:培养出的细胞在细胞免疫荧光检测下鉴定成功;5%和10%中药血清组均能明显抑制ASMC的增殖(P<0.05或P<0.01);ASMC培养上清液中,10%中药血清组的TGF-β1和IL-6浓度较哮喘模型组明显降低(P<0.05);与哮喘模型组比较,10%中药血清组对ADAM33蛋白的高表达下调作用更显著(P<0.01),10%、15%中药血清组及30%西药血清组对ETS-1蛋白的高表达下调更显著(P<0.01)。结论:降气平喘方可通过调控ADAM33和转录因子ETS-1表达,减少炎性细胞介质TGF-β1和IL-6释放以及改善气道重塑,达到干预和治疗哮喘的作用。 相似文献
993.
大规模蓝藻水华暴发对湖泊水生态系统健康和饮用水安全产生巨大危害,而湖泊水体磷是影响蓝藻水华暴发程度的重要生源要素。应对水体不同磷酸盐浓度,蓝藻高效运行磷酸盐转运系统和磷酸盐特殊转运系统,并合成多聚磷酸盐(聚磷)。蓝藻胞内存在颗粒态、胶体态和可溶态3种形态的聚磷,且不同形态的聚磷分布位置不同。不同蓝藻合成聚磷颗粒的大小、数量和合成期均有所差异。多聚磷酸盐激酶、多聚磷酸盐外切酶、多聚磷酸盐内切酶和P-AMP-磷酸转移酶分别催化聚磷的合成与分解。多聚磷酸盐是二价阳离子的螯合剂,也是磷酸盐及高能磷酸键的储藏库,为细胞生存提供阳离子、磷酸盐和能量,满足蓝藻生命活动过程中生理生化活动所需,具有抵御高温、高pH、紫外线和营养盐缺乏等环境胁迫的生理功能,提升其在不利环境中的生存能力。同时,在蓝藻水华持续暴发、湖泊藻型生境稳态和磷生物地球化学循环过程中聚磷发挥重要的生态功能。因此,蓝藻合成聚磷的分子生物学机制及生态功能研究能够阐明聚磷的存在如何改变湖泊水体—沉积物磷分配、食物网中磷传递等。而开展调控聚磷合成的技术研究,通过控制蓝藻合成聚磷来减轻蓝藻水华暴发规模,将为湖泊水体良性生态系统的重构提供新方法。 相似文献
994.
为研究深海能源土在负压开采过程中含气储层的力学特性,基于含气土赋存理论,提出一种能够控制含气量及气泡大小的制样方法,通过GDS标准应力路径三轴试验系统,开展深海能源土含气储层的固结排水试验研究,分析深海能源土在不同黏土含量及不同含气量下的力学响应规律。研究结果表明:围压变化对深海能源土含气储层的抗剪强度峰值大小影响显著,围压越大抗剪强度峰值越高;黏土含量是决定应力应变曲线变化趋势的关键影响因素,黏土含量越高试样抗剪强度越低,试样抵抗应变软化效应的能力越强;含气土比饱和土体承载能力更低,且承载能力随含气量的增大呈衰减趋势;黏土含量和含气量是深海能源土含气储层抗剪强度指标的重要影响因素,黏土含量、含气量越高,土体自身的总抗剪强度值越低。 相似文献
995.
江西冷水坑矿田是武夷山地区重要的银铅锌集中区之一。无论是世界上少有的斑岩型银铅锌矿床还是火山沉积 热液改造矿床都独具特色,具有很高的研究意义。该矿田的黄铁矿、闪锌矿和方铅矿等硫化物的δ34S值变化为-380‰~694‰,平均为187‰。大约为-411‰的δ13C值与峰值约为2‰的δ34S值的很窄分布表明成矿流体中的碳和硫来源于深部岩浆,并不排除地层提供一部分硫和碳的可能性。硫化物矿石的206Pb/204Pb、207Pb/204Pb和208Pb/204Pb比值分别为17771~17867、15564~15685和38235~38652。地层中火山岩、火山岩沉积岩以及变质岩石的 206Pb/204Pb比值为17899~18220,与矿石铅既有联系又有分离。然而,矿石和花岗斑岩的长石铅中206Pb/204Pb、207Pb/204Pb和208Pb/204Pb比值是相近的,它们在208Pb/204Pb 206Pb/204Pb和207Pb/204Pb 206Pb/204Pb图上落在同一条直线上。这条铅同位素混合线两个端员分别为上地壳和地幔。这些证据都强烈地支持了成矿物质主要来源于斑岩岩浆系统,地层对于成矿流体和物质的贡献不可或缺。冷水坑是一个典型的与次火山岩有关的岩浆热液成因的Ag Pb Zn矿田,成矿作用均发生于中国东部燕山中期陆内环境。 相似文献
996.
Badlands as a hot spot of petrogenic contribution to riverine particulate organic carbon to the Gulf of Lion (NW Mediterranean Sea) 下载免费PDF全文
Yoann Copard Frédérique Eyrolle Olivier Radakovitch Alain Poirel Patrick Raimbault Stéphanie Gairoard Christian Di‐Giovanni 《地球表面变化过程与地形》2018,43(12):2495-2509
Determining the riverine carbon fluxes to oceans is critical for an improved understanding of C budgets and biogeochemical cycles (C, O) over a broad range of spatial and time scales. Among the particulate organic carbon (POC) involved in these fluxes, those yielded by sedimentary rocks (petrogenic POC: pPOC) remain somewhat uncertain as to their source on continental surfaces. Based on time series from long‐term observatories, we refine the POC and sediments flux of the Rhône River, one of the major tributaries to the Mediterranean Sea. Radiocarbon measurements on a set of riverine samples and forward modelling were used to (i) determine a modelled pPOC content and pPOC/POC ratio for each sample set, (ii) assess pPOC flux delivered to the NW Mediterranean Sea, and (iii) estimate the badlands contribution from the Durance catchment to both the pPOC and to sediment discharges. The weighted pPOC flux contributes up to 26% of the POC flux (145 Gg yr‐1) discharged into the Mediterranean Sea, whereas the weighted pPOC content reaches 0.31 wt%. Despite their low contributive surface area (0.2%), badlands provide, respectively, 12, 3.5 and 14% of the pPOC, POC and sediment fluxes to the Rhône River. Consequently, such rocks can be considered as a major source of pPOC and sediments for the NW Mediterranean Sea and potentially for oceans. We suggest that river‐dominated ocean margins, such as the Rhône River, with badlands in their catchment could export a significant amount of pPOC to the oceans. Copyright © 2018 John Wiley & Sons, Ltd. 相似文献
997.
Sebastiano Foti Fabrice Hollender Flora Garofalo Dario Albarello Michael Asten Pierre-Yves Bard Cesare Comina Cécile Cornou Brady Cox Giuseppe Di Giulio Thomas Forbriger Koichi Hayashi Enrico Lunedei Antony Martin Diego Mercerat Matthias Ohrnberger Valerio Poggi Florence Renalier Deborah Sicilia Valentina Socco 《Bulletin of Earthquake Engineering》2018,16(6):2367-2420
Surface wave methods gained in the past decades a primary role in many seismic projects. Specifically, they are often used to retrieve a 1D shear wave velocity model or to estimate the VS,30 at a site. The complexity of the interpretation process and the variety of possible approaches to surface wave analysis make it very hard to set a fixed standard to assure quality and reliability of the results. The present guidelines provide practical information on the acquisition and analysis of surface wave data by giving some basic principles and specific suggestions related to the most common situations. They are primarily targeted to non-expert users approaching surface wave testing, but can be useful to specialists in the field as a general reference. The guidelines are based on the experience gained within the InterPACIFIC project and on the expertise of the participants in acquisition and analysis of surface wave data. 相似文献
998.
Alessandro?Caia Alberto?Giulio?Di?Lullo Giambattista?De?Ghetto Alberto?GuadagniniEmail authorView authors OrcID profile 《Stochastic Environmental Research and Risk Assessment (SERRA)》2018,32(9):2647-2666
The development of robust risk assessment procedures for offshore oil and gas operations is a major element for the assessment of the potential feedback between planned activities and the environment. We illustrate a methodological and computational framework conducive to (1) a quantitative risk analysis of deepwater well barrier failures and subsequent hydrocarbon release to the environment and (2) the analysis of the value of the deployment of conventional and/or innovative mitigation measures. Our methodological framework is grounded on historical records and combines the use of Dynamic Event Trees and Decision Trees from which we estimate probability of occurrence and impact of post-blowout events. Each sequence of response actions, which are undertaken immediately after the event or in the subsequent days, is considered within the context of appropriately structured event paths. This approach is conducive to an estimate of the expected value of key decisions and underlying technologies, with an emphasis on their potential to reduce the oil spill volume, which can critically impact the environment. Our study yields an original comparative analysis of diverse intervention strategies, and forms a basis to guiding future efforts towards the development and deployment of technologies and operating procedures yielding maximum benefit in terms of safety of operations and environmental protection. 相似文献
999.
Di Luo Zhiqiang Wu Tianjiu Zeng Xunhua Zhang Weina Zhao Huaishan Liu Guolin Xiao 《Studia Geophysica et Geodaetica》2018,62(3):466-484
The South Yellow Sea is a superimposed basin overlying Mesozoic-Cenozoic continental sediments, which in turn overlie Paleozoic-Mesozoic marine deposits that are now the target of hydrocarbon exploration. Strongly modified by multiple tectonic events, the marine sediments feature a large tectonic relief, with obvious horizontal anisotropy in seismic velocity, which significantly affects the seismic image quality. In this study, the sedimentary velocity anisotropy and its influence on image quality were analyzed using an analytical theory method, assuming transversely isotropic medium with vertical axis of symmetry (VTI), and using seismic and well-log data. Additionally, an anisotropic prestack time migration was used for the imaging of the field data. The results showed that the anisotropic pre-stack time migration processing could be used to significantly improve the accuracy of the seismic images in areas with distinct faults, offering clear images of accurately located fault planes and fault edges, thereby improving the lateral resolution of the seismic data and its signal-to-noise ratio. 相似文献
1000.
甘肃省CZB型竖直摆倾斜仪观测资料显示,形变异常与中国大陆近年具有较大影响的一些地震存在对应关系,分析发现震前异常变化有2种:①渐进式异常变化;②台阶式异常变化。研究发现,在不同地震台站,同种倾斜仪器在同一地震前异常表现不同,分析认为异常形态与台址岩性和岩石完整程度有关,与台站所处地质构造和周围山体地貌有关。 相似文献