几种鱼类培养细胞对不同干扰素敏感性的研究   总被引：5，自引：0，他引：5  

张义兵  王铁辉 《海洋湖沼通报》2000,(3):1-5

本文研究了四种鱼类培养细胞ＣＩＫ、ＣＡＢ、ＧＣＢ、ＢＲＥ对Ｈｕｉｆｎ－ａ,ＣＩＫ、ＣＡＢ、ＧＣＢ、ＧＲＥ、ＦＨＭ等五种鱼类培养细胞干扰素作用的敏感性。这四种鱼类培养细胞对ＨｕＩＦＮ－ａ不敏感,对五种鱼类培养细胞干扰素表现出相对一致的敏感性差异,其中ＧＲＥ细胞对鱼类干扰素最敏感,其次为ＣＡＢ、ＧＣＢ。ＣＩＫ细胞能产生高滴度的干扰素但对鱼类干扰素不敏感。不同病毒对干扰素作用的敏感性也不同。  相似文献   

孟加拉湾风暴Mala登陆期间地形敏感试验   总被引：1，自引：0，他引：1  

王曼  段旭  李华宏  刘建宇  符睿 《气象学报》2011,69(3):486-495

孟加拉湾是全球8个热带气旋易发生的地区之一。孟加拉湾风暴向偏北和偏东方向移动,会对中国青藏高原和西南地区形成重大影响,而孟加拉湾风暴的移动方向受到青藏高原和云贵高原大地形的影响很大。为了分析大地形对孟加拉湾风暴路径、结构变化和降水分布的作用和影响,文中利用WRF模式对2006年4月29—30日孟加拉湾风暴Mala的登陆过程进行数值模拟研究。试验结果表明:模拟风暴中心的路径和强度与实况虽有一定误差,但移动趋势均为东北方向,强度误差较小,表明WRF模式对本个例的模拟可以参考。通过不同地形高度敏感试验,分析风暴在登陆前后分别在全地形、半地形和零地形高度情况下的移动路径和速度、环流结构、动力结构以及在云南省产生的降水分布和强度。结果表明:风暴登陆前,大地形对风暴结构有间接影响,使高层出现倾斜。在风暴登陆过程中,地形的阻挡和摩擦作用能较明显影响风暴的移动路径和速度。风暴登陆后,地形抬升使风暴强度减弱,移动速度加快;结构由基本对称变为非对称,且斜压结构明显。地形对降水存在双重作用,一方面地形抬升使风暴产生的降水增加,另一方面地形摩擦使风暴强度减弱从而减少降水。  相似文献   

城区下垫面特征对成都地区一次暴雨过程影响的数值模拟   总被引：1，自引：0，他引：1  

谢娜  王咏青  施娟  倪萍 《高原气象》2011,30(6):1472-1480

利用NCEP/NCAR再分析资料对成都地区的一次区域性暴雨过程进行了诊断分析,并利用WRF模式对暴雨过程中城市下垫面的可能影响进行了敏感性试验。结果表明,WRF模式能较好地模拟出这次暴雨过程。改变城区下垫面特征后,与控制试验相比,敏感性试验的暴雨落区变化较小,强降雨中心面积有所增加,对四川盆地东部丘陵山区的温度增加影响...  相似文献   

浅层有限频率面波成像中的3D灵敏度核分析   总被引：1，自引：1，他引：0       下载免费PDF全文

鲁来玉  丁志峰  何正勤 《地球物理学报》2011,54(1):55-66

本文利用面波散射的模式耦合方法,基于波恩近似和远场假设,研究了有限频率面波三维灵敏度核,针对面波在工程应用中常遇到的水平分层的背景介质模型,计算了介质扰动引起的面波相位和幅度扰动的三维灵敏度核,分析了模式耦合对三维灵敏度核的影响.结果表明,仅考虑模式自身耦合的JWKB近似,介质密度和波速扰动引起的三维灵敏度核可以蜕化为...  相似文献   

Evaluation of brine discharge to rivers and streams: Methodology of rapid impact assessment     

Dirk Böhme 《Limnologica》2011,41(2):80-89

Induced by a brine discharge study for a submerse gas storage cavern project, a suitable methodology for rapid impact assessment had to be found. In this paper a simple stochastic, stationary model is described for assessment of intensity and temporal variability of chloride pollution at the regional scale of the rivershed. Chloride concentration is used as a proxy of salinity. It is assumed to be the result of deterministic process (flow-dependent) and stochastic variation (estimated for boundary conditions and tributaries by an additive error term based on PERT distribution). This approach is suited to conduct Monte Carlo simulations in order to calculate long-time means and percentiles of the prospective in-stream chloride concentration (exposure model). The biocoenoses exposed to this pollution has to be evaluated in terms of chloride tolerance. Herefore Maximum Field Distributions (MFD) of relevant species (aquatic macrophytes, macroinvertebrates, fish) were compiled and merged to Species Sensitivity Distributions (SSDs). Critical aspects of MFD data quality are discussed. Chloride model simulations representing different discharge scenarios provide exposure parameters (e.g. 90th percentile) that can be compared with SSD-derived protection levels (e.g. maximum loss of 10% of taxa) to quantify and evaluate possible adverse effects as well as potential recolonisation in case of load removal. Crosslinks to conservation issues are relevant in the selection and position of rare or protected species in the SSD. As an analysis of the German legal framework and technical guidelines revealed lack of guidance and best practices for such assessment and impact evaluation, recent experience highlights serious needs in applied research.  相似文献   

Comparison of SPT-N-based analysis methods in evaluation of liquefaction potential during the 1999 Chi-chi earthquake in Taiwan     

Muhsiung Chang  Chih-ping Kuo  Shih-hui Shau  Ron-eeh Hsu 《Computers and Geotechnics》2011

SPT-N-based methods have been adopted for liquefaction assessment of soils during earthquakes for decades. However, there has not been a consistent way of assessing the accuracy and applicability of these methods. The Chi-chi earthquake of 1999, which has been the most serious ground shaking in Taiwan within the century, caused extensive liquefactions in mid-west alluvial deposits of the island. This paper assesses the prediction accuracy of several SPT-N-based methods using liquefaction and non-liquefaction incidents observed during the earthquake. A sensitivity study on commonly adopted parameters shows that the SPT blow count and peak ground acceleration are most sensitive in computing liquefaction potential. By comparing the error in predicting liquefaction and non-liquefaction incidents, this study concludes that Tokimatsu and Yoshimi’s method is more accurate than the other methods. However, the differences between prediction errors of various methods are minimal, indicating all of the methods examined are applicable for the 1999 earthquake in Taiwan.  相似文献   

基于强度与稳定性的端头加固理论模型及敏感性分析     

罗富荣  江玉生  江华 《工程地质学报》2011,19(3):364-369

为确保盾构始发与到达的顺利进行,避免施工过程中发生端头土体失稳,引发地表沉陷、塌方等工程事故,基于土体强度与稳定性的基本理论,作者就如何确定端头土体纵向加固范围和建立砂土复合地层端头滑动模型进行了研究.在具体分析了现有端头加固理论模型的优缺点后,提出一种基于强度理论的荷载等效模型和基于稳定性理论的砂性土端头滑动模型.该...  相似文献   

横断山区近代气候变化的研究   总被引：6，自引：1，他引：5  

吴祥定  林振耀 《地理研究》1987,6(2):48-56

横断山地处我国西南的藏东、川西和滇西北一带,境内地形复杂,平均海拔在3000米以上。长期以来,由于资料短缺,对该地区历史时期气候变化研究甚少。经实地考察,作者获取若干树木年轮标本,辅以其它类型资料,对该地区最近数百年来的温度、降水变化及气候类型演替,予以初步分析。并论及气候变化的振幅与周期性。  相似文献   

日像仪的电磁干扰分析     

王威  陈志军  刘玉英  颜毅华  姬国枢 《天文研究与技术》2006,3(2):176-182

讨论了日像仪的干扰容限，列出了干扰源分布，估算出干扰测试仪灵敏度。计算了同步卫星干扰及干扰时间预测，也分析了中低轨道卫星干扰问题。对移动通信基站产生的干扰作了传播分析、计算，对脉冲雷达干扰作了谱分析及保守计算。  相似文献   

Quantifying the impact of small variations in fracture geometric characteristics on peak rock mass properties at a mining project using a coupled DFN–DEM approach     

《Computers and Geotechnics》2014

Using field data from Agnico-Eagle’s Meliadine gold project located in Nunavut Territory in northern Canada, a coupled DFN–DEM approach was used to evaluate the rock mass mechanical properties at REV. Variability in the structural data gathered on site and the variability associated with the stochastic modeling process have an impact on discrete fracture model (DFN) properties. Through a sensitivity analysis, this paper assesses the influence of a variation in the DFN model input parameters’ values on the rock mass peak properties – uniaxial compressive strength, Young modulus and Poisson ratio. The results not only highlight the possibilities associated with DFN–DEM modeling in characterizing rock mass properties at the engineering scale, they also provide a systematic way to assess the critical structural parameters controlling the rock mass properties.  相似文献