Stress Sharing Behavior and Its Mechanism during Consolidation Process in Composite Ground Improved by Sand Compaction Piles with Low Replacement Area Ratio     

S. -K. You  K. Oda  T. -H. Kim 《Marine Georesources & Geotechnology》2006,24(4):287-304

In order to accurately design a sand compaction pile (SCP) with low replacement area ratio, it is important to understand the mechanical interaction between the sand pile and clay ground and its mechanism during consolidation process in composite ground. In this article, therefore, a series of numerical analyses on composite ground improved by SCP with low replacement area ratio were carried out. The applicability of numerical analyses, in which an elasto-viscoplastic consolidation finite element method was applied, were confirmed by comparing the results obtained from a series of laboratory model tests with the composite ground improved by SCP. Through the results of the numerical analyses, mechanical behavior of the sand pile and clay in composite ground during consolidation is elucidated, together with a stress sharing mechanism between sand pile and clay.  相似文献   

基于网络药理学探究补阳还五汤治疗颈椎病的作用机制          下载免费PDF全文

王淑江  叶豪  龙胜利 《应用海洋学学报》2024,40(1):174

目的：基于网络药理学与分子对接技术分析补阳还五汤治疗颈椎病的作用机制。方法：使用TCMSP、化学专业数据库获取补阳还五汤的活性成分,并对潜在靶点进行预测及规范。分别从PharmGKB、DisGeNET、OMIM、GeneCards数据库中得到颈椎病疾病靶点,利用韦恩图获取补阳还五汤与颈椎病的交集靶点。通过CytoScape软件构建中药-活性成分-疾病靶点和蛋白质-蛋白质相互作用（PPI）网络,获得核心有效成分与关键靶点,利用David数据库对潜在靶点进行富集分析。最后运用AutoDock Vina软件对补阳还五汤核心有效成分与关键靶点进行分子对接验证。结果：共获得补阳还五汤治疗颈椎病的有效活性成分97个,包括槲皮素、山柰酚、黄芩素、木犀草素等;交集靶点64个,关键靶点有白细胞介素-6（IL-6）、肿瘤坏死因子（TNF）、丝氨酸/苏氨酸蛋白激酶1（AKT1）、白细胞介素-1B（IL-1B）等;主要涉及肿瘤坏死因子（TNF）、白细胞介素-17（IL-17）、磷脂酰肌醇3-激酶（PI3K）/蛋白激酶B（Akt）等信号通路,分子对接结果显示核心有效成分与关键靶点之间结合紧密,为补阳还五汤治疗颈椎病提供相应条件。结论：该研究在总体上预测了补阳还五汤治疗颈椎病的活性成分、靶点和信号通路,作用途径广泛,为下一步的临床应用提供参考及思路。  相似文献   

Documenting hurricane impacts on coral reefs using two-dimensional video-mosaic technology     

Arthur C. R. Gleason  Diego Lirman  Dana Williams  Nuno R. Gracias  Brooke E. Gintert  Hossein Madjidi  R. Pamela Reid  G. Chris Boynton  Shahriar Negahdaripour  Margaret Miller  & Philip Kramer 《Marine Ecology》2007,28(2):254-258

Four hurricanes impacted the reefs of Florida in 2005. In this study, we evaluate the combined impacts of hurricanes Dennis, Katrina, Rita, and Wilma on a population of Acropora palmata using a newly developed video‐mosaic methodology that provides a high‐resolution, spatially accurate landscape view of the reef benthos. Storm damage to A. palmata was surprisingly limited; only 2 out of 19 colonies were removed from the study plot at Molasses Reef. The net tissue losses for those colonies that remained were only 10% and mean diameter of colonies decreased slightly from 88.4 to 79.6 cm. In contrast, the damage to the reef framework was more severe, and a large section (6 m in diameter) was dislodged, overturned, and transported to the bottom of the reef spur. The data presented here show that two‐dimensional video‐mosaic technology is well‐suited to assess the impacts of physical disturbance on coral reefs and can be used to complement existing survey methodologies.  相似文献   

随机载荷下的疲劳损伤计算公式     

伍义生 《海洋工程》1994,(1)

本文推导了随机载荷下的疲劳损伤计算公式。数值计算结果表明：Ｐ．Ｈ．Ｗｉｒｓｃｈｉｎｇ给出的公式在宽带情况下与实际情况不符；Ｇ．Ｃｈａｕｄｈｕｒｙ给出的公式在窄带情况下与实际不符；本文绘出的公式不仅适合于窄带，也适合于具有各种不同带宽的宽带随机载荷。  相似文献   

黄河口及渤海中南部沉积物工程特性及其机理   总被引：3，自引：0，他引：3  

郑继民  沈谓铨  陆念祖  冯秀丽 《中国海洋大学学报(自然科学版)》1994,(2)

采用Ｋａｓｔｅｎ取样器从黄河口及渤海湾中南部海底沉积物中取样，对样品通过土工性质、微结构研究以及粘土矿物分析，阐明本研究区三维空间展布的海底沉积物形成机理及其工程地质规律，论证水动力作用和斜坡不稳定性对工程特性和微结构的重要影响．  相似文献   

非常规管节点疲劳寿命分析与计算   总被引：6，自引：1，他引：6  

谭开忍肖熙  黄小平 《海洋工程》2005,23(3):51-54,59

对非常规管节点的疲劳寿命进行了分析研究，用SESAM计算疲劳载荷，应用精细有限元分析计算热点应力，用规范的S—N曲线计算管节点的疲劳寿命。通过实例计算表明，这些处理对非常规管节点疲劳寿命分析与计算是很有效的。  相似文献   

潜艇疲劳载荷的概率模型   总被引：1，自引：0，他引：1  

黄小平  崔维成 《海洋工程》2003,21(3):18-23

探讨了建立潜艇疲劳载荷概率模型的方法，引入了正态分布和两参数威布尔分布两种概率模型。两参数威布尔分布较适合于用来描述潜艇下潜深度分布的概率特征。可根据潜艇的设计参数、任务及航行区域等因素来选取最可能的分布形式获得潜深分布密度函数。潜艇疲劳热点部位的应力(应变)幅值分布，可由应力(应变)和潜深的关系通过相应的变换得到。  相似文献   

秦皇岛昌黎黄金海岸的沙丘沉积和发育机理   总被引：7，自引：0，他引：7  

曾照爽  庄振业  祁兴芬  刘志杰 《海洋地质前沿》2003,19(7):23-27

昌黎黄金海岸长40km，分布1～1．5km宽的风成沙丘。主沙丘链高30～40m，顺岸线分布，与其斜交数列新月形横向沙丘链。沙丘以中细砂组成，分选极好，层理构造十分丰富。距今3～4ka以前，沙坝形成时就开始形成沙丘；1915年滦河新三角洲发育以来增加了风沙的输沙量，增高沙丘和扩宽了沙丘带。  相似文献   

黄河三角洲河道沉积规律研究Ⅱ. 建林边滩沉积作用机理     

范德江  陈彰榕  栾光忠 《中国海洋大学学报(自然科学版)》2001,31(2):237-242

通过对建林边滩沉积物粒度分布、粒度参数及水体流变性质的分析，阐述了黄河三角洲上河道水流属于牵引流范畴，与低含沙水流无本质上的差别，并探讨沉积物搬运和沉积的基本特征。  相似文献   

Rain-Flow and Reverse Rain-Flow Counting Method for the Compilation of Fatigue Load Spectrum     

宋玉普  王立成  李朝阳 《中国海洋工程》2001,(3):429-435

The rain-flow counting method is widely used to compile the fatigue load spectrum. The second stage counting of the rain-flow method is a troublesome process. In order to overcome this drawback, the rain-flow and reverse rain-flow counting method is proposed in this paper. In this counting method, the rule for counting of the rain-flow method is modified, so that the sequence of load-time need not be adjusted. This is a valid and useful method to count cycles and compile the load spectrum and it can be widely used in ocean engineering.  相似文献