大黄鱼白细胞介素17受体E-like的分子特征及进化分析          下载免费PDF全文

丁扬  敖敬群  艾春香  陈新华 《应用海洋学学报》2016,35(1):107-115

白细胞介素17受体(Interleukin 17 receptor,IL-17R)家族与IL-17细胞因子家族介导的各类反应有着密切联系.IL-17RE-like(IL-17REL)是一类最新发现的IL-17受体,其结构与IL-17RE相似,但尚未发现其配体.本研究克隆得到大黄鱼(Larimichthys crocea)IL-17REL(Lyc IL-17REL)的全长c DNA,其开放阅读框全长1 659个核苷酸,推断可编码一个由552个氨基酸组成的蛋白,含有信号肽、胞外段、跨膜区和胞内段.与其他物种的IL-17REL相似,Lyc IL-17REL蛋白的胞外段具有一个保守的FN I-like结构域,而胞内段缺少IL-17受体家族保守的SEFIR(SEF and IL-17R)结构域.多序列比对分析表明Lyc IL-17REL与日本河豚(Takifugu rubripes)IL-17REL的氨基酸序列同源性最高,序列一致性可达57.0%.系统进化分析表明,脊椎动物的IL-17受体家族可分为2类,IL-17RA/RB/RD为一类,IL-17RC/RE/REL为一类.其中鱼类及高等脊椎动物的IL-17REL与IL-17RE亲缘关系最近,并且推测二者可能是由同一基因从硬骨鱼类之前的物种中分化而来.组织分布表明Lyc IL-17REL在所有被检测的组织中为组成型表达,在黏膜相关组织如小肠和鳃中的表达量最高.大黄鱼受嗜水气单胞菌(Aeromonas hydrophila)诱导刺激后,Lyc IL-17REL在其头肾及鳃中的基因转录水平均显著上调.这表明Lyc IL-17REL可能在细菌感染引起的免疫反应中起着重要作用.  相似文献   

川西坳陷东坡沙溪庙组气藏成藏演化模式   总被引：1，自引：0，他引：1  

徐敏  刘建  林小云  熊山  牛斌莉 《现代地质》2018,32(5):953

川西坳陷东坡气藏主力产层为沙溪庙组,其圈闭类型以构造-岩性圈闭为主,多为致密砂岩储层,但断层发育,有效改善了储层物性,断砂匹配样式与构造演化对油气成藏过程有重要影响。基于前人已有的认识,通过沙溪庙组气藏成藏动力演化、气水分布特征及生烃期次分析,结合构造演化、成藏幕次等研究,认为沙溪庙组天然气成藏受构造古隆起、断砂配置、储层物性、构造演化影响,形成了“构造控向、断砂控运、储层控藏、演化控调”的成藏演化模式,同中存异,高庙子地区古构造的控制作用更为明显,而中江地区岩性控制作用占主导。沙溪庙组气藏间歇性充注具“燕山期三幕成藏,喜山期调整改造”的成藏特征,多期构造演化和较强的储层非均质性影响了含气饱和度,导致沙溪庙组气藏分布、气藏产能差异大。  相似文献   

Sedimentology and Sequence Stratigraphy of Marine to Lacustrine Deltaic Deposits in a Craton Basin and Their Controlling Factors: Shan 2 Member–He 8 Member (Guadalupian–Lopingian, Permian), Southeast Ordos Basin, North China     

SHAN Xin  YU Xinghe  Peter ?CLIFT  LI Yalong  JIN Lin  SU Dongxu  DU Yonghui  ZHOU Jinsong  HAN Xiaoqin 《《地质学报》英文版》2018,92(1):268-285

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Tectono–Thermal Evolution, Hydrocarbon Filling and Accumulation Phases of the Hari Sag, in the Yingen–Ejinaqi Basin, Inner Mongolia, Northern China     

YANG Peng  REN Zhanli  XIA Bin  TIAN Tao  ZHANG Yong  QI Kai  REN Wenbo 《《地质学报》英文版》2018,92(3):1157-1169

This work restored the erosion thickness of the top surface of each Cretaceous formations penetrated by the typical well in the Hari sag, and simulated the subsidence burial history of this well with software BasinMod. It is firstly pointed out that the tectonic subsidence evolution of the Hari sag since the Cretaceous can be divided into four phases: initial subsidence phase, rapid subsidence phase,uplift and erosion phase, and stable slow subsidence phase. A detailed reconstruction of the tectonothermal evolution and hydrocarbon generation histories of typical well was undertaken using the EASY R_0% model, which is constrained by vitrinite reflectance(R_0) and homogenization temperatures of fluid inclusions. In the rapid subsidence phase, the peak period of hydrocarbon generation was reached at c.a.105.59 Ma with the increasing thermal evolution degree. A concomitant rapid increase in paleotemperatures occurred and reached a maximum geothermal gradient of about 43-45℃/km. The main hydrocarbon generation period ensued around 105.59-80.00 Ma and the greatest buried depth of the Hari sag was reached at c.a. 80.00 Ma, when the maximum paleo-temperature was over 180℃.Subsequently, the sag entered an uplift and erosion phase followed by a stable slow subsidence phase during which the temperature gradient, thermal evolution, and hydrocarbon generation decreased gradually. The hydrocarbon accumulation period was discussed based on homogenization temperatures of inclusions and it is believed that two periods of rapid hydrocarbon accumulation events occurred during the Cretaceous rapid subsidence phase. The first accumulation period observed in the Bayingebi Formation(K_1 b) occurred primarily around 105.59-103.50 Ma with temperatures of 125-150℃. The second accumulation period observed in the Suhongtu Formation(K_1 s) occurred primarily around84.00-80.00 Ma with temperatures of 120-130℃. The second is the major accumulation period, and the accumulation mainly occurred in the Late Cretaceous. The hydrocarbon accumulation process was comprehensively controlled by tectono-thermal evolution and hydrocarbon generation history. During the rapid subsidence phase, the paleo temperature and geothermal gradient increased rapidly and resulted in increasing thermal evolution extending into the peak period of hydrocarbon generation,which is the key reason for hydrocarbon filling and accumulation.  相似文献   

Late Cenozoic Sedimentary Evolution of Pagri‐Duoqing Co graben,Southern End of Yadong‐Gulu Rift,Southern Tibet   总被引：1，自引：0，他引：1  

HA Guanghao  WU Zhonghai  HE Lin  WANG Shubing 《《地质学报》英文版》2018,92(3):972-987

The north trending rifts in southern Tibet represent the E–W extension of the plateau and confirming the initial rifting age is key to the study of mechanics of these rifts. Pagri–Duoqing Co graben is located at southern end of Yadong–Gulu rift, where the late Cenozoic sediments is predominately composed of fluvio-lacustrine and moraine. Based on the sedimentary composition and structures, the fluvio-lacustrine could be divided into three facies, namely, lacustrine, lacustrine fan delta and alluvial fan. The presence of paleo-currents and conglomerate components and the provenance of the strata around the graben indicate that it was Tethys Himalaya and High Himalaya. Electron spin resonance (ESR) dating and paleo-magnetic dating suggest that the age of the strata ranges from ca. 1.2 Ma to ca. 8 Ma. Optically stimulated luminescence (OSL) dating showed that moraine in the graben mainly developed from around 181–109 ka (late Middle Pleistocene). Combining previous data about the Late Cenozoic strata in other basins, it is suggested that 8–15 Ma may be the initial rifting time. Together with sediment distribution and drainage system, the sedimentary evolution of Pagri could be divided into four stages. The graben rifted at around 15–8 Ma due to the eastern graben-boundary fault resulting in the appearance of a paleolake. Following by a geologically quiet period about 8–2.5 Ma, the paleolake expanded from east to west at around 8–6 Ma reaching its maximum at ca. 6 Ma. Then, the graben was broken at about 2.5 Ma. At last, the development of the glacier separated the graben into two parts that were Pagri and Duoqing Co since the later stages of the Middle Pleistocene. The evolution process suggested that the former three stages were related to the tectonic movement, which determined the basement of the graben, while the last stage may have been influenced by glacial activity caused by climate change.  相似文献   

论羌塘盆地沉积演化   总被引：4，自引：2，他引：2       下载免费PDF全文

王剑  付修根 《中国地质》2018,45(2):237-259

羌塘盆地位于可可西里—金沙江缝合带与班公湖—怒江缝合带之间,其沉积演化对于正确认识古、中特提斯洋盆构造演化具有重要意义。本文通过沉积序列、岩相古地理、沉积盆地分析,结合年代地层学等最新研究成果,建立了羌塘中生代盆地(T3—K1)的沉积演化模式,讨论了羌塘盆地演化与古特提斯洋盆关闭、中特提斯洋盆形成的关系。羌塘中生代盆地(T3—K1)是由冲洪积相沉积超覆开始的,总体上为一个向上变深的海侵序列,表现为冲洪积相、河湖相逐渐演化为滨海相及浅海相,可划分出3种典型的沉积超覆类型及5个主要阶段的沉积演化序列。羌塘中生代盆地整体上为一个由前陆盆地演化为裂谷盆地、被动大陆边缘盆地、最终转化为活动大陆边缘盆地并萎缩消亡的叠合盆地。羌塘早—中三叠世前陆盆地的关闭,与古特提斯洋盆的关闭有关,羌塘中生代盆地(T3—K1)的演化受中特提斯洋的快速开启及关闭的制约。  相似文献   

柴达木盆地1:50 000尕海镇幅水文地质图数据集   总被引：1，自引：1，他引：0       下载免费PDF全文

党学亚  曾庆铭  杨炳超  顾小凡 《中国地质》2018,45(S2):30-38

尕海镇幅位于柴达木盆地东北缘的巴音河山前平原,是1：50 000国际标准图幅。其水文地质图是根据中国地质调查局组织编制并即将颁布实施的《水文地质图编制规范（1：50 000）》的基本要求,结合区内发展建设的需求,利用2016年1：50 000水文地质调查最新获取的尕海镇幅钻孔抽水试验成果数据（本次施工以及收集已有钻孔资料共48个钻孔）,水化学（61个水样）、同位素（12个同位素样）和土壤易溶盐（55个土样）分析成果数据,地下水位统测成果数据（68个统测点）,以及已有资料与成果数据编制而成。编图以地下水系统理论和生态水文地质理论为指导,按地下水系统、水文地质结构、含水岩组及富水性、地下水补给-径流-排泄条件、地下水化学特征、地下水水位埋深与流场、地下水与生态植被关系、地下水开发利用等分类加工处理数据形成水文地质图数据集,使大量的信息在图面上以主图结合镶图的形式主次分明、层次清晰地加以展现,以便为当地水资源开发利用和生态环境保护提供直观易用的地下水资料支撑。  相似文献   

祁连山新元古代——早古生代火山作用与铁-铜多金属成矿     

李向民  余吉远  王国强  黄博涛  武鹏 《地质通报》2018,37(4):693-703

祁连山造山带新元古代—早古生代是板块构造演化与成矿的最重要时段,铁、铜多金属矿产资源丰富,成矿作用与新元古代—早古生代火山作用密切相关。根据矿床产出构造位置,将祁连山铁、铜多金属矿床分为4类:大陆裂谷型铁(铜)矿床、岛弧-岛弧裂谷型铜多金属矿床、陆缘裂谷型铜多金属矿床、扩张脊型铜矿床。镜铁山铁(铜)型矿床是新元古代大陆裂谷火山作用过程中热水沉积作用的产物;东沟铜矿为晚寒武世大洋扩张脊火山作用的产物;白银矿田铜多属矿床是奥陶纪与岛弧-岛弧裂谷火山作用的产物;石居里铜矿是晚奥陶纪弧后扩张脊有关火山作用的产物;红沟铜矿则是晚奥陶世陆缘裂谷火山作用的产物。  相似文献   

川西坳陷新场构造带须家河组超压演化与流体的关系   总被引：1，自引：0，他引：1  

黄丽飞  楼章华  陈明玉  朱蓉  王君 《地质通报》2018,37(5):954-964

沉积盆地超压体系是油气勘探与开发过程中一个不容忽视的问题,不仅影响了地质流体的运移和聚集,更为勘探带来安全隐患。以实测地压和油田水化学数据为基础,对川西坳陷新场构造带须四段和须二段现今地层水矿化度与现今压力系数关系进行比较,结合地层水特征系数和阴阳离子关系,综合前人研究结果,对须四段和须二段压力演化史与地层水演化过程进行分析,考察川西坳陷须家河组超压系统演化与地层水演化的耦合关系。结果表明,须家河组超压发育与地层水具有密切的联系:(1)须家河组储层段压力分布范围较广,在弱超压至超强压之间,须二段属于中超压而须四段属于超高压,平面分布中须二段探测井中矿化度随压力系数增加而减少,须四段则相反;(2)在压实过程中,由于流体排驱受阻导致"欠压实"超压的产生,随着超压的不断积聚,局部出现裂缝,导致地层水更加强烈的混合作用和运移;(3)生烃作用导致自生压力增大,地层水离子水岩作用强烈,造成流体包裹体与现今地层水离子成分分异;(4)构造挤压抬升过程中,须四段裂缝不发育,压力进一步升高,须二段则产生泄压,出现了凝析水和水侵现象,造成须四段和须二段现今地层水特征的差异。  相似文献   

Role of heterogeneities in jointing (fracturing) of geological media: Numerical analysis of fracture mechanisms     

《Comptes Rendus Geoscience》2018,350(8):452-463

Fracture process is investigated using finite-difference simulations with a new constitutive model. It is shown that both geometry and fracture mechanism itself depend on the preexisting heterogeneities that are stress concentrators. In the brittle regime (low pressure, P), Mode-I fractures propagate normal to the least stress σ₃ from the imposed weak zones. At high P, shear deformation bands are formed oblique to σ₃. At intermediate values of P, the fracture process involves both shear banding and tensile cracking and results in the initiation and propagation of pure dilation bands. The propagating band tip undulates, reacting on the failure mechanism changes, but its global orientation is normal to σ₃. The σ₃-normal fractures are joints. There are thus two types of joints resulting from Mode-I cracking and dilation banding, respectively. The obtained numerical results are in good agreement with and explain the results from previous similar experimental study.  相似文献