参附注射液建立自发性高血压病大鼠肝阳上亢证模型的研究          下载免费PDF全文

周梦  杨文丽  刘晓庆 《应用海洋学学报》2018,34(12):120-122

目的：探讨参附注射液建立自发性高血压大鼠（SHR）模型的可能性。方法：将30只3月龄SPF级健康雄性自发性高血压大鼠称重，随机分为SHR组，附子汤组，参附注射液低、中、高剂量组，每组6只。各组采用对应药物灌胃进行模型制备，另取同品系同周龄雄性魏-凯二氏大鼠（WKY）6只作为正常对照组（WKY组）。观察参附注射液对SHR大鼠24h饮水量、易激惹程度、痛阈、睑结膜充血及收缩压的影响。结果：附子汤组及参附注射液中、高剂量组造模后均出现了易激惹程度增高、睑结膜充血程度增高、饮水量增多、痛阈降低、收缩压升高等肝阳上亢的表现，与WKY组及SHR组比较，差异有统计学意义（P<0.05)，表明造模成功。结论：参附注射液可以制备新型高血压肝阳上亢证模型，但是具体造模机制以及造模药物用量需待进一步探讨确定。  相似文献   

两株南极枝孢霉属真菌Cladosporium sp.NJF4和NJF6的次级代谢产物研究          下载免费PDF全文

常俊男  田晓清  樊成奇  黄金昌  陆亚男  韩清华 《极地研究》2020,32(1):60-67

南极因其独特的自然环境成为潜在、重要的微生物资源库,是产生新型生物活性物质和先导化合物菌株的潜在种源地,南极微生物正在成为创新药物研究新的重要资源。虽然近年来对南极微生物次级代谢产物的研究逐渐增加,但与温带和热带微生物研究相比仍处于初级阶段。对从南极普里兹湾海洋沉积物中获得的两株枝孢霉属真菌Cladosporium sp. NJF4和NJF6进行次级代谢产物分离及结构鉴定,获得20个化合物。化合物结构类型包括甾醇(1)、倍半萜类(7—8)、生物碱类(9—14)、二酮哌嗪(2—5、15—17)、芳香酸(6、18—19)等,其中倍半萜类(7—8)为首次从枝孢霉属真菌中分离得到,以上研究将为丰富南极微生物次级代谢产物库奠定一定的研究基础。  相似文献   

一种污水排海的近远区计算与控制方法──以大亚湾水容量计算及污水排海为例     

韩保新  彭海君  曾小清  胡康萍  吕先林 《热带海洋学报》1996,(4)

针对点容量计算中混合区限制的要求，采用了动量积分法、经验公式法和有限差分法，分别对污水排放后可能引起的近区、过渡区和远区的污水浓度变化进行了模拟预测，并就一定的限制性条件对容量点近区、高浓度混合区及容量点远区影响范围进行了分析。在大亚湾水容量计算及污水排海规划中的应用表明，该法具有计算机时较省、精度相对较高等优点。  相似文献   

SPOT5 HRG严格物理模型转换成RPC模型的方法   总被引：1，自引：1，他引：0  

程晓庆  孙建 《地理空间信息》2008,6(4):107-109

SPOT5 HRG使用的越来越多,使用SPOT5 HRG进行测图,就必然需要推导SPOT5 HRG严格物理模型,通过推导SPOT5 HRG严格物理模型,我们发现该模型计算量很大,为了解决这个问题,我们使用虚拟点阵将RPC模型和严格物理模型联系起来,这样就能将SPOT5 HRG物理模型转换为RPC模型,最后用实际生产数据检验了该RPC模型的正确性  相似文献   

Indium Enrichment in the Meng'entaolegai Ag-Pb-Zn Deposit, Inner Mongolia, China   总被引：3，自引：0，他引：3  

Qian Zhang    Xiaoqing Zhu    Yuliang He  Junjie Jiang  Dapeng Wang 《Resource Geology》2006,56(3):337-346

Abstract. The Meng'entaolegai In-rich Ag-Pb-Zn deposit is located in the eastern part of Inner Mongolia. It is one of the In-richest deposits in China. Large amounts of quartz and sulfide minerals constitute a hydrothermal quartz-sulfide vein deposit within a Hercynian acidic granite massif, which occupies an area of about 400 km². Thirty-six orebodies, controlled strictly by the E-W trend faults, are found in the orefield of 6 km in length from east to west and 200 to 1,000 m in width from south to north. The ore minerals are mainly galena, sphalerite and pyrite, and subordinate chalcopyrite, arsenopyrite, cassiterite and stannite with many Ag-minerals. The gangue minerals are mainly quartz, calcite, sericite and chlorite. Economic components of the deposit are dominated by Pb andZn (reserves of Pb and Zn are 0.17 Mt and 0.37 Mt, and their grades are 1 % and 2.3 %, respectively), with Ag, Sn, In and Cd (1,800 t Ag, >2,000 t Sn, >500 t In and 1,800 t Cd) as by-products. Indium is highly enriched in ores and its contents are 9 to 295 ppm in ores and 85 to 2,660 ppm in sphalerite. Analytical results show that the ore-forming fluid of this deposit contains 0.8–3.5 ppm In and 4–36 ppm Sn, and the two elements show a very good positive correlation with a correlation coefficient of 0.8672, while the correlation between In and Zn in the ore-forming fluids, with a correlation coefficient of 0.5723, is not as good as that between In and Sn. This indicates that indium has an affinity with tin in the ore-forming fluids. The authors think that this is probably the main reason why those In-rich deposits spread over the world are simultaneously enriched in tin.  相似文献   

良好植被区泥石流防治初探   总被引：10，自引：0，他引：10  

陈晓清  崔鹏  韦方强 《山地学报》2006,24(3):333-339

通过对近年来发生在良好植被区的几次重大泥石流、滑坡灾害的考察,发现植被在泥石流、滑坡形成中的作用有待于进一步认识。通过分析,当中小强度降雨激发下,植被能够削减泥石流、滑坡灾害的规模,甚至抑制泥石流、滑坡灾害的发生;当降雨超过一定阀值后,在水作用下,植被不但不能削减灾害规模,反而增大灾害的规模。在这类地区,简单地使用一般的防治措施,已经不能满足防灾、减灾的需要,客观要求针对这些地区泥石流灾害的形成原因、危害特征,研究防治对策。经初步研究提出3点防治措施:1)加强泥石流滑坡灾害的预测预报工作;2)在重点区域设置自动雨量记录报警装置;3)特别针对漂木拦挡,采取新型结构减轻泥石流的危害。  相似文献   

REE characteristics of the Fanshan alunite deposit in Zhejiang Province, China     

何玉良  张乾  邵树勋  朱笑青  祝朝辉  王大鹏 《中国地球化学学报》2006,25(4):366-373

1 Introduction Alunite [KAl3(SO4)2(OH)6] is a very important non-ferrous metal resource, so many countries throughout the world have made great investments in research on the mechanism of its formation, its geological characteristics and applications. O…  相似文献   

Gold Occurrence and Ore Genesis,Yata Micro—Disseminated Gold Deposit,Guizhou,Southwest China     

朱笑青  王中刚 《中国地球化学学报》2002,21(4):370-373

The mode of occurrence of gold in the Yata micro-disseminated gold deposit is ap-proached through chemical phase studies coupled with ore-dressing monitoring and micro-beam analysis.The results showed that gold occurred for the most part as ultra-microscopic particles adsorbed on the surfaces or fracture planes of pyrite and other sulphides.The proportions of gold of different occurrences were estimated solutions containing nanometer-sized gold particles were prepared following the hydrolysis-reduction procedure and the adsorption of nanometer-sized gold on ordinary sulphides and rocks was experimentally determined.It is evident that sulphides are good adsorbents of gold and this is consistent with geological observations.  相似文献   

THE SEDIMENTATION AND DREDGING OF GUANTING RESERVOIR     

Xiaoqing YANG  Shanzheng LI  Shiqi ZHANG 《国际泥沙研究》2003,18(2)

1 INTRODUCTION Guanting Reservoir is located on the Yongding River (a large tributary of the Haihe River) and at the border of Beijing Municipality and Hebei Province. The reservoir receives three tributaries: the Sanggan River with a drainage area of 25,840 km2, the Yanghe River with 16,170 km2, and the Guishui River with 852 km2. The drainage area above the reservoir is 43,402 km2. The reservoir has two arms. The Sanggan River and Yanghe River join the Yongding River at the ups…  相似文献   

空间移动信息服务客户端实现   总被引：5，自引：0，他引：5  

余涛平  闫利  谢智颖  左小清 《武汉大学学报(信息科学版)》2003,28(1):80-85

介绍了LBS及其相关技术——定位技术、GIS技术和互联网技术，并从开发平台出发比较了当前的几种LBS解决方案。针对空间信息服务的内容和特点，从系统的关键性技术出发，分析了客户端解决方案的数据模型和功能模型，最后介绍了系统实现的情况。  相似文献