排序方式： 共有5条查询结果，搜索用时 0 毫秒
1
1.
Gozari Mohsen Bahador Nim Jassbi Amir Rez Mortazavi Mohammad Seddiq Hamzehei Sam Eftekhar Ebrahim 《海洋学报(英文版)》2019,38(12):84-90
Screening bioactive natural products from bacteria is a determinative step in the drug discovery programs. The present study aim to isolate actinobacteria from the Oman Sea sediments for determining the effects of different culture media and treatments on the yield of the isolation process, and measure the DPPH radical scavenging and Artemia cytotoxic activity of culture extracts of the actinobacterial isolates. A total of 290 actinobacterial isolates were collected from 14 sediment samples. Heat treatment(40.68%) and M_4 medium(29.31%) exhibited the maximum isolation rates of actinobacteria. Streptomyces isolates were dominantly distributed in all of the investigated stations according to 16 S rRNA gene sequencing. The distribution pattern of Streptomyces followed a depth-dependent frequency trend, whereas the members of rare genera including Micromonospora, Nocardia Actinoplanes, Nocardiopsis, Saccharopolyspora and Crossiella were distributed in deeper stations. Approximately,25% of the examined isolates could scavenge 90% of 10~(–4) mol/L DPPH solutions at 1 250 μg/mL final concentration of their ethyl acetate culture extracts. Furthermore, the most potent extracts could scavenge DPPH radicals with IC50 ranges from 356.8 to 566.4 μg/mL. Brine shrimp cytotoxicity tests showed that 38.88% of the examined culture extracts exhibited LC_(50) lower than 1 000 μg/mL against the Artemia cells. Moreover, the most potent culture extracts exhibited LC_(50) range from 335.4 to 534.4 μg/mL. Phylogenetic analysis by 16 S rRNA gene sequence revealed that the OS 005, OS 263 and OS 157 closely related to Streptomyces djakartensis, Streptomyces olivaceus and Nocardiopsis dassonvillei respectively. These results suggested the widespread distribution of the antioxidant and cytotoxic producing actinobacteria in the Oman Sea sediments, which could be considered as promising candidates for the discovery of microbial bioactive compounds. 相似文献
2.
3.
Liquid sloshing is a common phenomenon in the liquid tanks transportation. Liquid waves lead to fluctuating forces on the tank wall. Uncontrolled fluctuations lead to large forces and momentums. Baffles can control these fluctuations. A numerical method, which has been widely used to model this phenomenon, is Smoothed Particle Hydrodynamics(SPH). The Lagrangian nature of this method makes it suitable for simulating free surface flows. In the present study, an accurate Incompressible Smoothed Particle Hydrodynamics(ISPH) method is developed and improved using the kernel gradient correction tensors, particle shifting algorithms, k–ε turbulence model, and free surface particle detectors. Comparisons with the experimental data approve the ability of the present algorithm for simulating shallow water sloshing. The main aim of this study is to investigate the effects of the vertical baffle on the damping of liquid sloshing. Results show that baffles number has a major role in sloshing fluctuation damping. 相似文献
4.
尼泊尔8.1级地震对中国西藏地区造成的震害特征分析 总被引：1，自引：0，他引：1
2015年4月25日尼泊尔发生8.1级地震,对我国西藏地区造成较大人员伤亡与房屋破坏,道路、通讯等生命线工程及水利等基础设施损坏严重。本文介绍了本次地震的基本情况,并在现场地震烈度调查和地震损失评估的基础上,对灾区震害进行了分析,给出了灾区房屋类别与破坏情况以及生命线系统与各行业的受损情况。通过分析此次地震的灾害特点,指出了灾区在抗震设防中存在的问题,并提出加大地震地质灾害的防治力度,科学编制恢复重建规划,加强防震减灾宣传,提高农牧民抗震设防意识,加强农牧区房屋建筑的指导和监管等建议,以减少地震造成的人员伤亡和财产损失,促进西藏地区经济和社会的和谐发展。 相似文献
5.
An experimental study is conducted to measure small-strain shear modulus of clay-cement mixture using bender element apparatus
setup in a triaxial cell. Bender element tests were conducted on cement-treated soils and the results were analyzed to study
the variation of shear modulus properties of soil specimens at different cement contents, confining pressures, curing times,
and compaction moisture contents. Based on the obtained results increasing the cement ratio has a significant effect on the
small-strain shear modulus of the treated soils, and this effect signifies with increasing the moisture content and curing
time. Rates of shear modulus enhancements due to cement content, curing time, and compaction moisture content are quantified
and presented. In this study, a clay–cement–water ratio formulation is proposed that enables one to calculate cement and water
contents required to obtain specific small-strain shear modulus. 相似文献
1