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Transportation networks daily provide accessibility and crucial services to societies. However, they must also maintain an acceptable level of service to critical infrastructures in the case of disruptions, especially during natural disasters. We have developed a method for assessing the resilience of transportation network topology when exposed to environmental hazards. This approach integrates graph theory with stress testing methodology and involves five basic steps: (1) establishment of a scenario set that covers a range of seismic damage potential in the network, (2) assessment of resilience using various graph-based metrics, (3) topology-based simulations, (4) evaluation of changes in graph-based metrics, and (5) examination of resilience in terms of spatial distribution of critical nodes and the entire network topology. Our case study was from the city of Kathmandu in Nepal, where the earthquake on April 25, 2015, followed by a major aftershock on May 12, 2015, led to numerous casualties and caused significant damage. Therefore, it is a good example for demonstrating and validating the developed methodology. The results presented here indicate that the proposed approach is quite efficient and accurate in assisting stakeholders when evaluating the resilience of transportation networks based on their topology.  相似文献   
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More than 150 landslides originated in the eastern part of the Czech Republic (region of the Flysch Outer Western Carpathians—hereinafter, OWC) due to soil saturation caused by antecedent precipitation and long lasting and intensive rainfalls on 16–18 May 2010 (>300 mm as measured by some stations). As a consequence, a multitude of small failures originated 88% of which was smaller than 104 m2. Most landslides are characterised as shallow (<10 m) or middle–deep (10–30 m) incipient (rather short travel) landslides, debris slides and soil slips spatially clustered to a geological domain underlain by rather weak thin-bedded flysch and unconsolidated Quaternary deposits. An exception to this is represented by a kilometre-long rockslide (∼2–3 mil m3) affecting tectonically weakened and weathered claystone/mudstone-dominated flysch on the southern slope of Mt. Girová (the Beskydy Mountains). The rockslide is one of the largest long runout landslides in the territory of the Czech Republic activated over the past few decades as it reaches the dimensions of the largest documented Holocene long runout landslides in the Czech part of the OWC. A majority of the May 2010 landslide events developed inside older (Holocene or historic) landslide terrains, which points to their spatial persistency and recurrent nature. In spite of the fact that the May 2010 landslide event was not as destructive as some previous landslide activisation in the OWC region (e.g. July 1997 event), it left many slope failures at the initial stage of their potential future reactivation.  相似文献   
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The sedimentary infills of subglacially eroded bedrock troughs in the Alps are underexplored archives for the timing, extent and character of Pleistocene glaciations but may contain excellent records of the Quaternary landscape evolution over several glacial–interglacial cycles. The onset of sedimentation in these bedrock troughs is often reflected by diamicts and gravels directly overlying bedrock in the deepest basin segments. Subglacial or proglacial depositional environments have been proposed for these coarse‐grained basal units but their characteristics and origin remain controversial. This article presents results from drill cores that recovered a coarse‐grained basal unit in a major buried bedrock‐trough system in the Lower Glatt Valley, northern Switzerland. The excellent core recovery allowed a detailed study combining macroscopic, microscopic and geochemical methods and gives unprecedented insights into the transition from erosion to deposition in overdeepened bedrock troughs. These results show that the basal infill comprises diamicts, interpreted as subglacial tills, separated by thin sorted interbeds, originating from subglacial cavity deposition. The stacking of these units is interpreted to represent repeated switching between a coupled and decoupled ice–bed‐interface indicating an ever‐transforming mosaic of subglacial bed conditions. Decoupling in response to high basal water pressures is probably promoted by the confined subglacial hydraulic conditions resulting from the bedrock acting as aquitards, the narrow reverse sloping outlet and a large catchment area. While stratigraphic and lithological evidence suggests that erosion and the onset of basal sedimentation occurred during the same glaciation, different scenarios for the relative timing of infilling in relation to formation and glaciation of the bedrock trough are discussed. Overlying deltaic and glaciolacustrine sediments suggest deposition during subsequent deglaciation of the bedrock trough. The basal sediment characteristics are in agreement with previous reports in hydrogeological and seismic exploration and suggest the occurrence of similar basal successions in other subglacially overdeepened basins in the Alps and elsewhere.  相似文献   
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The lipids in a sediment core from Lake Valencia, a hypereutrophic freshwater lake in Venezuela, are examined to understand environmental changes over the last ∼13,000 years. From the latest Pleistocene to the earliest Holocene, total organic carbon (TOC) substantially increased from 2.2 to 10%, while total organic carbon over total nitrogen (TOC/TN) decreased from as high as 34 to as low as 10. Correspondingly, the concentration of terrestrially derived triterpenoids markedly decreased, and the dominant n-alkane shifted from C31 to C23 or C25. During the same period, algal biomarkers such as botryococcenes, dinosterol, isoarborinol, C20 HBIs and 1,15C32 keto-ol markedly increased in abundance. These changes suggested a greater contribution of algal organic matter at the onset of the Holocene, which was concurrent with increasing rainfall and the formation of a permanent lake (Lake Valencia) in the Aragua Valley, Venezuela. The age profile of Paq, a n-alkane based proxy, showed large oscillations (0.20–0.81), reflecting historical variations in source strength of submerged/floating vs. terrestrial/emergent OM inputs. An abrupt increase in tetrahymanol abundance at ∼7,260 cal years BP suggests the establishment of an oxic–anoxic boundary in the lake’s water column. After reaching its maximum abundance at ∼2,100 cal year BP, botryococcenes, a biomarker of Botryococcus braunii, gradually decreased to below the detection limit in the uppermost sediments, while different algal/microbial biomarkers such as diploptene, dinosterol and isoarborinol substantially increased. These different historical profiles of algal/microbial biomarkers reflect different responses of source organisms to environmental changes throughout this period. The δ13C determinations presented exceptionally enriched values for botryococcene isomers (−7.7 to −15.1‰), indicating the utilization of bicarbonate as carbon sources in an extremely productive ecosystem.  相似文献   
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Marine waters from six sites around Hong Kong with varying levels of sewage pollution were examined for noroviruses (NoVs) by PCR cloning and sequencing of a highly-variable N-terminal region of the VP1 capsid gene, at the ORF1-ORF2 junction of NoV. Phylogenetic analysis of genogroups GI- and GII-specific PCR clones obtained from different marine sites indicated that human NoV GI.1 and GII.4 strains are the most prevalent genotypes circulating in Hong Kong waters. GI- and GII-specific TaqMan-based real-time PCR assays targeting the ORF1-ORF2 junction of NoVs were used to quantify NoV particles in marine water samples in parallel with total Escherichia coli counts which were enumerated on TBX medium. No correlation of any significance between NoV and E. coli counts was observed which highlighted the inadequacy in using E. coli as a fecal indicator to predict the level of NoVs in marine waters to protect public health.  相似文献   
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A recent study demonstrated that 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) may have an adverse effect on the reproduction in marine medaka (Oryzias melastigma), but the molecular mechanisms remain largely unknown. In this study, we investigated the protein expression profiles of male and female gonads of O. melastigma exposed to dietary BDE-47 at two dosages (0.65 and 1.30 μg/g/day, respectively) for 21 days. Extracted proteins were labeled with iTRAQ and analyzed on a MALDI TOF/TOF analyzer, as results, 133 and 144 unique proteins were identified in testis and ovary, respective, and they exerted dose- and sex-dependent expression patterns. In testis, among the 42 differentially expressed proteins; down-regulation of histone variants and parvalbumins implicated BDE-47 may disrupt the spermatogenesis and induce sterility in fishes. In ovary, 38 proteins were differentially expressed; the elevation of vitellogenins and apolipoprotein A–I expression indicated BDE-47 acts as an estrogen-mimicking compound and led to reproductive impairment in O. melastigma.  相似文献   
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