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901.
902.
手足口病(HFMD)是一种多发于儿童的常见传染病。近年来,中国HFMD发病人数逐年上升,疾病疫情也日益受到社会广泛关注。虽已有不少相关研究,但对于探测其时空异质性及量化潜在影响因子解释力的研究仍然较少。本文采用地理探测器及贝叶斯时空层次模型,对2009-2013年京津唐地区HFMD发病率的时空异质性进行分析,并量化各影响因子及其两两交互作用对HFMD发病率的解释力。结果表明:① HFMD的相对风险存在时间异质性,其发病风险在春夏季(5-7月)达到峰值,而冬季(12-次年2月)发病风险最低;② HFMD的相对风险存在空间异质性,在经济发达的地区HFMD发病率较高;③ 影响HFMD发病率时间异质性的主要气象因子为平均温度、累积降水、相对湿度,解释力分别为0.38,0.27,0.13,且交互作用都大于独自影响的作用,如平均温度和相对湿度、平均温度和降水,平均温度和风速两两交互的解释力分别为0.43, 0.40, 0.42。通过研究京津唐地区HFMD发病率的时空异质性以及影响因子的量化状况,为本地区HFMD的预防和控制提供理论依据。  相似文献   
903.
Gao  Yuting  Gao  Yang  Liu  Baoyu  Jiang  Yang 《GPS Solutions》2021,25(3):1-15
GPS Solutions - The tropospheric delay is an important error source in the Global Positioning System (GPS) positioning and navigation applications. Although most of the tropospheric delays can be...  相似文献   
904.
A cavity expansion–based solution is proposed in this paper for the interpretation of CPTu data under a partially drained condition. Variations of the normalized cone tip resistance, cone factor, and undrained-drained resistance ratio are examined with different initial specific volume and overconsolidation ratio, based on the exact solutions of both undrained and drained cavity expansion in CASM, which is a unified state parameter model for clay and sand. A drainage index is proposed to represent the partially drained condition, and the critical state after expansion and stress paths of cavity expansion are therefore predicted by estimating a virtual plastic region and assuming a drainage-index–based mapping technique. The stress paths and distributions of stresses and specific volume are investigated for different values of drainage index, which are also related to the penetration velocity with comparisons of experimental data and numerical results. The subsequent consolidation after penetration is thus predicted with the assumption of constant deviatoric stress during dissipation of the excess pore pressure. Both spherical and cylindrical consolidations are compared for dissipation around the cone tip and the probe shaft, respectively. The effects of overconsolidation ratio on the stress paths and the distributions of excess pore pressure and specific volume are then thoroughly investigated. The proposed solution and the findings would contribute to the interpretation of CPTu tests under a random drained condition, as well as the analysis of pile installation and the subsequent consolidation.  相似文献   
905.
Most of previous analyses on the active earth pressure were performed in two-dimensional cases using the Mohr-Coulomb (M-C) failure function to describe the soil strength. However, all failures of retained slopes indicate a somewhat three-dimensional (3D) feature, and the M-C function is found to overestimate the tensile strength of cohesive soil. In this work, a kinematic limit analysis–based approach is developed for computing the 3D active earth pressure resulting from cohesive backfills. The concept of tensile strength cutoff is adopted to implement the reduction or elimination of tensile strength from the strength envelope. An extended 3D horn failure mechanism that is associated with the modified strength envelope is developed to characterize the collapse of retained slopes. The resultant of active earth pressure is evaluated from the work rate balance equation and expressed as an unfactored coefficient. The obtained results indicate that less support provided by the wall is required when allowing the existence of soil cohesion and 3D effects and that eliminating the tensile strength can observably increase the active earth pressure, especially for the backfill with a great level of cohesion.  相似文献   
906.
精氨酸/赖氨酸特异性半胱氨酸蛋白酶(Metacaspase)在浮游植物程序性细胞死亡(programmed cell death.PCD)过程中起着关键作用。本文利用生物信息学方法分析metacaspase基因在浮游植物中的分布,并以海洋球石藻(Emilianiahuxleyi)metacaspases(EhMCs)为代表分析其结构和功能,依据Uniprot和String数据库挖掘与metacaspase功能相关并参与浮游植物PCD过程的互作蛋白。结果发现:共计29条、四种类型的metacaspases分布于11种浮游植物中,它们的metacaspase蛋白一级结构存在明显差异,但位于p20的组氨酸和半胱氨酸活性位点均具有高度的保守性;EhMCs三级结构与酵母的metacaspase十分相似,暗示它们具有类似的功能;浮游植物metacaspases与多种蛋白存在直接或间接的互作关系,在细胞PCD过程、响应环境胁迫和能量代谢等方面发挥重要作用。另外.metacaspase的磷酸化修饰可能在浮游植物PCD信号转导过程中起调节作用。  相似文献   
907.
Radio observation is one of important methods in solar physics and space science. Sometimes, it is almost the sole approach to observe the physical processes such as the acceleration, emission, and propagation of non-thermal energetic particles, etc. So far, more than 100 solar radio telescopes have been built in the world, including solar radiometers, dynamic spectrometers, and radioheliographs. Some of them have been closed after the fulfillment of their primary scientific objectives, or for their malfunctions, and thus replaced by other advanced instruments. At the same time, based on some new technologies and scientific ideas, various kinds of new and much more complicated solar radio telescopes are being constructed by solar radio astronomers and space scientists, such as the American E-OVSA and the solar radio observing system under the framework of Chinese Meridian Project II, etc. When we plan to develop a new solar radio telescope, it is crucial to design the most suitable technical parameters, e.g., the observing frequency range and bandwidth, temporal resolution, frequency resolution, spatial resolution, polarization degree, and dynamic range. Then, how do we select a rational set of these parameters? The long-term observation and study revealed that a large strong solar radio burst is frequently composed of a series of small bursts with different time scales. Among them, the radio spike burst is the smallest one with the shortest lifetime, the narrowest bandwidth, and the smallest source region. Solar radio spikes are considered to be related to a single magnetic energy release process, and can be regarded as an elementary burst in solar flares. It is a basic requirement for the new solar radio telescope to observe and discriminate these solar radio spike bursts, even though the temporal and spatial scales of radio spike bursts actually vary with the observing frequency. This paper presents the scaling laws of the lifetime and bandwidth of solar radio spike bursts with respect to the observing frequency, which provide some constraints for the new solar radio telescopes, and help us to select the rational telescope parameters. Besides, we propose a spectrum-image combination mode as the best observation mode for the next-generation solar radio telescopes with high temporal, spectral, and spatial resolutions, which may have an important significance for revealing the physical essence of the various non-thermal processes in violent solar eruptions.  相似文献   
908.
吕阳 《海洋科学》2018,42(10):94-102
文章用文献计量与科学知识图谱方法呈现海洋药物研究态势与热点,旨在为海洋药物研究提供参考。本文以SCIE(Science Citation Index Expanded)为数据源,以1980~2017年海洋药物领域论文为研究对象,采用文献计量与知识图谱可视化分析方法,结合Excel、VOSviewer软件,对论文年代分布、研究机构、期刊、作者、高被引论文及研究热点进行分析。结果表明,海洋药物研究的热点方向为海洋天然产物、抗菌活性、细胞毒性、海绵等,应重点关注海洋天然产物及其抗菌药理作用的研究。世界范围内关于海洋药物研究的论文数量呈逐年上升趋势,美国在该领域研究占据绝对优势,其发文量、总被引和H指数均占绝对地位。该领域主要发文期刊为《Marine Drugs》、《Journalof Natural Products》。发文机构中中国科学院位列世界第一,但整体论文质量欠佳,中国在该领域研究水平有待加强,论文影响力仍需提高。  相似文献   
909.
黄河三角洲是中国唯一一块保存最完整、最典型、最年轻的湿地生态系统,由于其地理位置优越、自然资源丰富等特点,在国际上备受关注。该文在已有资料分析、现场地质调查、遥感数据分析的基础上,构建了黄河三角洲湿地资源地质环境评价指标体系,采用定量与定性相结合的方法,将黄河三角洲湿地地质环境质量分为5个等级(优、良、一般、较差和差),研究结果表明,该地区19个县(市、区)中湿地地质环境资源质量为良的有8个,质量一般的为11个,总体处于健康-疾病的临界状态。并基于以上研究成果,针对性地提出了黄河三角洲湿地资源保护对策。  相似文献   
910.
浅水地震勘探对于了解近海底地质构造具有重要意义,目前已被广泛用于油气开发、近岸工程等领域。表面多次波的存在干扰了有效波信息,影响了资料品质,造成解释假象,如何有效地压制多次波,已成为浅水地震勘探中的关键问题。表面多次波衰减方法(SRME)是一种去除海面相关多次波效果较好的技术方法,但是,一般认为SRME技术并不适合于浅水区域。分析了SRME去除多次波的基本原理,并将其应用于海洋高分辨率浅水区域多次波的去除。实际处理效果表明,使用SRME技术处理后的叠加剖面多次波去除效果明显,剖面基底清楚,断面清晰。通过对SRME技术应用于浅水区域的探讨,证实了SRME技术在海洋高分辨率地震勘探浅水区域应用效果较好。  相似文献   
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