肝素酶Ⅰ对合成的肝素五糖的酶解作用及对其抗Xa因子活性的影响     

于广利  管华诗  Jawed Fareed 《中国海洋大学学报(自然科学版)》2001,31(4):529-535

研究肝素酶Ⅰ(来源于Flavobacterumheparinase，EC4.2.2.7)对人工合成的且含有与抗凝血酶Ⅲ特定结合位点的肝素五糖(SHP)的酶解作用，并对酶解作用的动力学进行研究。利用强阴离子高效液相色谱(SAX-HPLC)对酶解混合物进行分离，利用质谱(ESIMS)和核磁共振波谱(1H-NMR)技术对得到的二糖和三糖的结构进行确证。研究结果表明，这种被作为肝素反向试剂的肝素酶Ⅰ可水解人工所合成的肝素五糖，从而使之丧失抗Xa因子活性。  相似文献   

苏澳一与那国岛断面上黑潮流速结构的特征及其季节变化     

管秉贤 《海洋科学集刊》1981,(18):1-18

自北赤道流延伸而来的黑潮，起源于我国台湾省的东南海域。当黑潮沿着台湾岛东岸北上时，它的主轴通过苏澳-与那国岛断面，自北太平洋进入我国东海，成为我国东、黄海海流系统的“大动脉”。显然，黑潮的流速结构及其变化，对东、黄海水文特征的分布、变化以及我国东部沿海地区的气候，特别是旱涝现象，都有着密切的关系。所以，有关这一问题的探讨是很有意义的。而欲研究黑潮的上述问题，取苏澳-与那国岛断面作为探讨的核心是很合适的，因为这个断面不仅离黑潮源地较近，而且位于黑潮进入东海首当其冲的关键性区域。 关于黑潮在这一断面上海洋水文状态的变化情况，日本学者须田晥次(K.Suda,1937-1938)曾作过广泛的研究，他主要分析了黑潮源地区域标量场(温、盐、密度等)的逐月变化特征。本文拟引用须田当年所列举的温、盐度资料，来研究黑潮的流速结构(主要是流速分布和输送量)及其季节变化，并结合现有的海面风应力资料，试图对黑潮输送量的季节变化及其原因作一初步的探讨，并作为进一步研究黑潮变动规律的参考。  相似文献   

藻类功能食品的物质基础与研究开发现状   总被引：3，自引：0，他引：3  

周德庆  管华诗 《中国海洋大学学报(自然科学版)》1995,(Z1)

对藻类功能食品的研究和开发现状作综述报道。涉及的主要内容有：作为功能食品物质基础的食物纤维、ＰＵＦＡ、维生素、矿物质和微量元素、氨基酸以及其它有生理活性的物质。  相似文献   

赤道暖池区漂流浮标运动轨迹分析     

侍茂崇  刘士军  周冰  温之平 《中国海洋大学学报(自然科学版)》1993,(Z2)

TOGA—COARE强化观测期间,对赤道暖池区海流作了多种方法、多层次的观测;根据美国释放的漂流浮标不同时刻位置的资料,分别对赤道及其南、北海域的表层漂流状况作了计算分析,指出:从1°N向北存在单一的北向流;从1°N～1°S这个近赤道区域内为东向流;1°N～2°S区域为过渡区,以东向流为主,个别浮标出现涡旋状运动。2°S以南为一反时针运动的大涡旋。  相似文献   

A proposed directional function and wind-wave directional spectrum   总被引：4，自引：0，他引：4  

Wen Shengchang  Wu Kejian  Guan Changlong  Sun Shicai  Zhang Dacuo 《海洋学报(英文版)》1995,14(2):155-166

Ａｐｒｏｐｏｓｅｄｄｉｒｅｃｔｉｏｎａｌｆｕｎｃｔｉｏｎａｎｄｗｉｎｄ－ｗａｖｅｄｉｒｅｃｔｉｏｎａｌｓｐｅｃｔｒｕｍ￥ＷｅｎＳｈｅｎｇｃｈａｎｇ；ＷｕＫｅｊｉａｎ；ＧｕａｎＣｈａｎｇｌｏｎｇ；ＳｕｎＳｈｉｃａｉａｎｄＺｈａｎｇＤａｃｕｏ（Ｒｅｃｅｉ...  相似文献   

气候转型与早期人类迁徙   总被引：4，自引：0，他引：4  

吴文祥  刘东生 《海洋地质与第四纪地质》2001,21(4):103-109

目前的旧石器考古证据表明，更新世早期可能发生了两次人类迁徙浪潮，时间分别在1.8-1.6MaBP和1.0MaBP左右，第一阶段，古人类演化为直立人并开始走出非洲、迁徙至其它中低纬度的热带－亚热带地区；第二阶段，直立人开始占据中高纬度的温带和干旱－半干旱地区。这两个阶段也是第四纪气候发生转型、环境产生重大调整的时期。二者在发生时间上的一致性揭示了它们之间的内在联系，推测气候转型时期环境转变是这两次人类迁徙浪潮的主要驱动力。  相似文献   

Chronic sublethal effects of the water soluble fractions of no. 2 fuel oils on the marine isopod, Sphaeroma quadridentatum     

Wen Yuh Lee 《Marine environmental research》1978,1(1):5-17

Two series of experiments were carried out to assess the long-term effects of the water soluble fractions (WSF) of fuel oils on the marine isopod, Sphaeroma quadridentatum. In one experiment, juvenile isopods (one month old) were exposed to sublethal concentrations (0·1% to 15% WSF) of a fuel oil (Baytown, Exxon) at room temperatures of 24 ± 1–6°C for nine months. These isopods survived to maturity and reproduced. However, growth rate was adversely affected at concentration ≥ 3% WSF and fecundity was depressed at concentrations ≥ 1% WSF. Survival of offspring in clean seawater was dependent to a large extent on the history of the previous generation. Offspring from groups exposed to ≥ 1% WSF experienced high mortality (> 70% within five weeks) even in clean seawater. This may imply that a population of Sphaeroma exposed to WSF as low as 0·2 ppm may eventually disappear, although animals can grow to maturity and reproduce at concentrations < 3 ppm.In another experiment, adult Sphaeroma (three months old) were subjected to the WSFs of four fuel oils (Baton Rouge, Baytown, Montana and New Jersey) for one month. Fecundity was depressed at a concentration > 15% WSF, regardless of the kind of fuel oil. On the other hand, the number of young produced bythe surviving females varied with the type of fuel oil for the same level of WSF. This may be attributed to different relative amounts of toxic components present in the WSF.  相似文献   

长江口泥沙絮凝静水沉降动力学模式的试验研究   总被引：10，自引：1，他引：10  

关许为  陈英祖 《海洋工程》1995,(1)

细颗粒泥沙在咸水中的絮凝沉降是河流泥沙向海输送过程中在河口区发生的重要现象，是河口拦门沙形成与发育的主要原因之一。本文根据室内模拟试验研究，提出长江口泥沙絮凝静水沉降的二级动力学模式，通过该式求得不同泥沙含量和盐度情况下絮凝沉降的衰减系数，半衰期和平均沉降速率等动力学参数，定量地分析泥沙含量和盐度对泥沙絮凝沉降过程的影响。  相似文献   

Improved form of wind wave frequency spectrum   总被引：5，自引：0，他引：5  

Wen Shengchang 《海洋学报(英文版)》1989,8(4):467-483

The lower frequency part of the theoretical wind wave spectrum proposed by the authors (Wen et al. , 1988a, b,c) has been improved and the form of spectrum is appreciably simplified. In addition to the field data collected in the Bohai Sea region and used in the previous papers, those obtained in the Huanghai Sea, the East China Sea and the South China Sea have been employed so that the improved spectra can be verified on a more extensive observational basis. Computed results agree with the observations well. Further comparisons have been made between the proposed spectra and the JONSWAP spectrum. Though the two types of spectrum are close to each other in form, the former shows, as a whole, better agreement with the observation than the latter. By introducing an improved relation between the peak-ness factor and significant wave steepness, the spectrum contains only significant wave height and period as parameters. For spectra given in this form, the computed peak frequencies coincide approximately wit  相似文献   

Stress and deformation of offshore piles under structural and wave loading   总被引：3，自引：0，他引：3  

J. A. Eicher  H. Guan  D. S. Jeng   《Ocean Engineering》2003,30(3):369-385

Various offshore structures, especially large structures such as Tension Leg Platforms (TLP), are usually supported by concrete piles as the foundation elements. The stress distribution within such a large structure is a dominant factor in the design procedure of an offshore pile. To provide a more accurate and effective design for offshore foundation systems under axial and lateral wave loads, a finite element model is employed herein to determine the stresses and displacements in a concrete pile under similar loading conditions. A parametric study is also performed to examine the effects of the stress distribution due to the changing loading conditions.  相似文献