参附注射液建立自发性高血压病大鼠肝阳上亢证模型的研究          下载免费PDF全文

周梦  杨文丽  刘晓庆 《应用海洋学学报》2018,34(12):120-122

目的：探讨参附注射液建立自发性高血压大鼠（SHR）模型的可能性。方法：将30只3月龄SPF级健康雄性自发性高血压大鼠称重，随机分为SHR组，附子汤组，参附注射液低、中、高剂量组，每组6只。各组采用对应药物灌胃进行模型制备，另取同品系同周龄雄性魏-凯二氏大鼠（WKY）6只作为正常对照组（WKY组）。观察参附注射液对SHR大鼠24h饮水量、易激惹程度、痛阈、睑结膜充血及收缩压的影响。结果：附子汤组及参附注射液中、高剂量组造模后均出现了易激惹程度增高、睑结膜充血程度增高、饮水量增多、痛阈降低、收缩压升高等肝阳上亢的表现，与WKY组及SHR组比较，差异有统计学意义（P<0.05)，表明造模成功。结论：参附注射液可以制备新型高血压肝阳上亢证模型，但是具体造模机制以及造模药物用量需待进一步探讨确定。  相似文献   

Analytical study of ground motion caused by seismic wave propagation across faulted rock masses          下载免费PDF全文

J.C. Li  N.N. Li  S.B. Chai  H.B. Li 《国际地质力学数值与分析法杂志》2018,42(1):95-109

Studying seismic wave propagation across rock masses and the induced ground motion is an important topic, which receives considerable attention in design and construction of underground cavern/tunnel constructions and mining activities. The current study investigates wave propagation across a rock mass with one fault and the induced ground motion using a recursive approach. The rocks beside the fault are assumed as viscoelastic media with seismic quality factors, Q_p and Q_s. Two kinds of interactions between stress waves and a discontinuity and between stress waves and a free surface are analyzed, respectively. As the result of the wave superposition, the mathematical expressions for induced ground vibration are deduced. The proposed approach is then compared with the existing analysis for special cases. Finally, parametric studies are carried out, which includes the influences of fault stiffness, incident angle, and frequency of incident waves on the peak particle velocities of the ground motions.  相似文献   

两株南极枝孢霉属真菌Cladosporium sp.NJF4和NJF6的次级代谢产物研究          下载免费PDF全文

常俊男  田晓清  樊成奇  黄金昌  陆亚男  韩清华 《极地研究》2020,32(1):60-67

南极因其独特的自然环境成为潜在、重要的微生物资源库,是产生新型生物活性物质和先导化合物菌株的潜在种源地,南极微生物正在成为创新药物研究新的重要资源。虽然近年来对南极微生物次级代谢产物的研究逐渐增加,但与温带和热带微生物研究相比仍处于初级阶段。对从南极普里兹湾海洋沉积物中获得的两株枝孢霉属真菌Cladosporium sp. NJF4和NJF6进行次级代谢产物分离及结构鉴定,获得20个化合物。化合物结构类型包括甾醇(1)、倍半萜类(7—8)、生物碱类(9—14)、二酮哌嗪(2—5、15—17)、芳香酸(6、18—19)等,其中倍半萜类(7—8)为首次从枝孢霉属真菌中分离得到,以上研究将为丰富南极微生物次级代谢产物库奠定一定的研究基础。  相似文献   

宁夏香山-天景山弧形断裂带新活动特征及1709年中卫南71/2级地震形变带   总被引：5，自引：1，他引：4       下载免费PDF全文

张维岐  焦德成  柴炽章  宋方敏  汪一鹏 《地震地质》1988,10(3):12

本文根据野外地质填图和水系位移测量结果,论述了香山-天景山弧形断裂带新生代有两个不同活动性质的阶段,即早期阶段的强烈挤压和晚期阶段的左旋走滑兼挤压。分析、讨论了不同活动阶段的时间界限和转变原因。指出了1709年中卫南71/_2级地震形变带的表现形式、延伸范围  相似文献   

Occurrence and evolution of the Xiaotangshan hot spring in Beijing, China   总被引：1，自引：0，他引：1  

Zhou Haiyan  Zhou Xun  Chai Rui  Yu Lan  Liu Chunhui  Li Liangping 《Environmental Geology》2008,53(7):1483-1489

Thermal groundwater occurs in bedrock aquifers consisting of the dolomite of the Wumishan Group of the Jixianin System and the Cambrian carbonate in the Xiaotangshan geothermal field near the northern margin of the North China Plain, China. The hot water in the geothermal field of basin-type discharges partly in the form of the Xiaotangshan hot spring under natural conditions. The hot water has TDS of less than 600 mg/L and is of Na·Ca-HCO₃ type. The geothermal water receives recharge from precipitation in the mountain area with elevation of about 500 m above sea level to the north of the spring. Thermal groundwater flows slowly south and southeast through a deep circulation with a residence time of 224 years estimated with the Ra–Rn method. The Xiaotangshan hot spring dried up in the middle of the 1980s owing to the increasing withdrawal of the hot water in the geothermal field in the past decades. The water level of the geothermal system still falls continually at an annual average rate of about 2 m, although water temperature changes very little, indicating that the recharge of such a geothermal system of basin-type is limited. Over-exploitation has a dramatic impact on the geothermal system, and reduction in exploitation and reinjection are required for the sustainable usage of the hot water.  相似文献   

A nitrate and silicate budget in the equatorial Pacific Ocean: a coupled physical–biological model study     

M. -S. Jiang  F. Chai  R. C. Dugdale  F. P. Wilkerson  T. -H. Peng  R. T. Barber   《Deep Sea Research Part II: Topical Studies in Oceanography》2003,50(22-26):2971

A coupled physical–biological model was developed to simulate the low-silicate, high-nitrate, and low-chlorophyll (LSHNLC) conditions in the equatorial Pacific Ocean and used to compute a detailed budget in the Wyrtki box (5°N–5°S, 180–90°W) for the major sources and cycling of nitrogen and silicon in the equatorial Pacific. With the incorporation of biogenic silicon dissolution, NH₄ regeneration from organic nitrogen and nitrification of ammonia in the model, we show that silicon recycling in the upper ocean is less efficient than nitrogen. As the major source of nutrients to the equatorial Pacific, the Equatorial Undercurrent provides slightly less Si(OH)₄ than NO₃ to the upwelling zone, which is defined as 2.5°N–2.5°S. As a result, the equatorial upwelling supplies less Si(OH)₄ than NO₃ into the euphotic zone in the Wyrtki box, having a Si/N supply ratio of about 0.85 (2.5 vs. 2.96 mmolm⁻² day⁻¹). More Si(OH)₄ than NO₃ is taken up with a Si/N ratio of 1.17 (2.72 vs. 2.33 mmolm⁻² day⁻¹) within the euphotic zone. The difference between upwelling supply and biological uptake is balanced by nutrient regeneration and horizontal advection. Excluding regeneration, the net silicate and nitrate uptakes are nearly equal (1.76 vs. 1.84 mmolm⁻² day⁻¹). However, biogenic silica export production is slightly higher than organic nitrogen (1.74 vs. 1.59 mmolm⁻² day⁻¹) following a 1.1 Si/N ratio. In the central equatorial Pacific, low silicate concentrations limit diatom growth; therefore non-diatom new production accounts for most of the new production. Higher silicate supply in the east maintains elevated diatom growth rates and new production associated with diatoms dominate upwelling zone. In contrast, the new production associated with small phytoplankton is nearly constant or decreases eastward along the equator. The total new production has a higher rate in the east than in the west, following the pattern of surface silicate. This suggests that silicate regulates the diatom production, total new production, and thereby carbon cycle in this area. The modeled mean primary production is 48.4 mmolCm⁻² day⁻¹, representing the lower end of direct field measurements, while new production is 15.0 mmolCm⁻² day⁻¹, which compares well with previous estimates.  相似文献   

Research on the spectral analysis and test method of period signals in monthly mean sea level     

Ma Jirui  Tian Suzhen  Zheng Wenzhen  Chai Xinmin 《海洋学报(英文版)》1995,14(2):181-190

Ｒｅｓｅａｒｃｈｏｎｔｈｅｓｐｅｃｔｒａｌａｎａｌｙｓｉｓａｎｄｔｅｓｔｍｅｔｈｏｄｏｆｐｅｒｉｏｄｓｉｇｎａｌｓｉｎｍｏｎｔｈｌｙｍｅａｎｓｅａｌｅｖｅｌ￥ＭａＪｉｒｕｉ；ＴｉａｎＳｕｚｈｅｎ；ＺｈｅｎｇＷｅｎｚｈｅｎａｎｄＣｈａｉＸｉｎｍｉｎ（Ｒ...  相似文献   

Several significant hydrographic characteristics and their formation mechanism in the South China Sea during the spring and summer of 1998   总被引：1，自引：1，他引：1  

Xu Jianping  Chai Fei  Liu Zenghong  Zhu Bokang 《海洋学报(英文版)》2003,22(4):491-502

INTRODUCTIONTheSCSisthelargestmarginseainthewestoftheNorthPacificOcean .Theprevailingwindinwinterisnortheast,whileinsummeritissouthwest .Itisstilluncertainthathowthecirculationandtemperature -salinityfieldassociatewiththemonsoonforcingandaccompanywithseveralkindsofvariationsbeforeorafterthesummermonsoonburst .DuringSECMEXin 1 998,twointensiveobservationperiods (IOP)havebeencarriedoutntheSCS (Fig 1 ) :IOP1 ,from 1 0Aprilto 5May ;IOP2 ,from 1 2JunetoJuly 6 ,inordertounderstandthe…  相似文献   

头足类视觉特性的电生理研究 Ⅰ.无针乌贼视网膜电图的特性   总被引：1，自引：0，他引：1  

郑微云  柴敏娟 《海洋学报》1981,3(3):472-476

乌贼是重要的海洋水产资源之一,对其视觉特性的研究在理论上和实践上显然都有一定的意义。视网膜电图(ERG)作为网膜的综合电活动是反映视觉特性的一个良好指标。乌贼的ERG的特性至今缺乏系统的研究。本文对其ERG的波形和适应特性作了较详细的描述。续文将报导对ERG的光谱敏感性的分析。  相似文献   

重金属锌,铅对菲律宾蛤仔的急性毒性试验   总被引：14，自引：1，他引：14  

刘琼玉  洪华生 《台湾海峡》1997,16(1):50-54

本文研究了必需元素Ｚｎ及非必需元素Ｐｂ对菲律宾蛤仔的急性毒性作用，得到Ｚｎ对其的４８ｈＬＤ５０和９６ｈＬＤ５０分别为１４７．９１、１６．４０ｍｇ／ｄｍ＾３；Ｐｂ对其的４８ｈＬＤ５０和９６ｈＬＤ５０分别为３１．６２、１４．２８ｍｇ／ｄｍ＾３。估算得到Ｚｎ、Ｐｂ对菲律宾蛤仔的安全浓度分别为０．８２、０．７１ｍｇ／ｄｍ＾３。  相似文献