Production of the Blood Pressure Lowing Peptides from Brown Alga （ Undaria pinnatifida ）     

Sato Minoru Oba Takashi Hosokawa Takao Yamaguchi Toshiyasu Nakano Toshiki Saito Tadao Muramoto Koji Kahara T akashi Funayama Katsura Kobayashi Akio Nakano Takahisa 《中国海洋大学学报(英文版)》2005,4(3):209-213

Brown alga （ Undaria pinnatifida） was treated with alginate lyase and hydrolyzed using 17 kinds of proteases and the inhibitory activity of the hydrolysates for the angiotensin-I-converting enzyme （ACE） was measured. Four hydrolysates with potent ACE-inhibitory activity were administered singly and orally to spontaneously hypertensive rats （SHRs）. The systolic blood pressure of SHRs decreases significantly after single oral administration of the brown alga hydrolysates by pro- tease S ＇ Amano＇ （from Bacillus stearothermophilus） at the concentration of 10 （mg protein） （kg body weight）^ - 1. In the 17 weeks of feeding experiment, 7-week-old SHRs were fed standard diet supplemented with the brown alga hydrolysates for 10 weeks. In SHRs fed 1.0 and 0.1% brown alga hydrolysates, elevating of systolic bloodpressure was significantly suppressed for 7 weeks. To elucidate the active components, the brown alga hydrolysates were fractionated by 1-butanol extraction and HPLC on a reverse-phase column. Seven kinds of ACE-inhibitory peptides were isolated and identified by amino acid composition analysis, sequence analysis, and LC-MS with the results Val-Tyr, Ile-Tyr, Ala-Trp, Phe-Tyr, Val-Trp, Ile-Trp, and Leu-Trp. Each peptide was determined to have an antihypertensive effect after a single oral administration in SHRs. The brown alga hydrolysates were also confirmed to decrease the blood pressure in humans.  相似文献   

Turbulence,convection, and mixing in red giant stars: Some empirical approaches based on high resolution spectroscopy     

Takashi Tsuji 《Astrophysics and Space Science》1986,118(1-2):227-235

The differential velocity field in cool stars can be measured effectively on photographic plates by the use of a PDS micro-densitometer, from which it is shown that radial velocity gradients are larger for stars with larger turbulent velocities, which are determined from the high resolution echellograms. This indicates that the stellar turbulence may have something to do with the differential velocity field in stellar atmospheres. As an observational probe of the mixing processes in red giant stars, stellar abundances that are sensitive to mixing are determined on the basis of high resolution Fourier Transform spectroscopy. For example, the¹²C/¹³C ratio has now been determined for large number of red giant stars and shows characteristic changes through the first red giant branch to the asymptotic giant branch, including both the pre-thermal pulsing and the thermal pulsing phases. This information, together with additional information on the¹⁶O/¹⁷O ratio and on CNO abundances, provides useful constraints on the theory of mixing in red giant stars.Paper presented at the IAU Third Asian-Pacific Regional Meeting, held in Kyoto, Japan, between 30 September-6 October, 1984.  相似文献   

Phase boundary between ilmenite and perovskite structures in MnGeO3 determined by in situ X-ray diffraction measurements     

Daisuke Yamazaki  Eiji Ito  Yoshinori Tange  Takashi Yoshino  Shuangmeng Zhai  Hiroshi Fukui  Anton Shatskiy  Tomoo Katsura  Ken-ichi Funakoshi 《Physics and Chemistry of Minerals》2007,34(4):269-273

In situ X-ray observations of the phase transition from ilmenite to perovskite structure in MnGeO₃ were carried out in a Kawai-type high-pressure apparatus interfaced with synchrotron radiation. The phase boundary between the ilmenite and perovskite structures in the temperature range of 700–1,400°C was determined to be P (GPa) = 16.5(±0.6) − 0.0034(±0.0006)T (°C) based on Anderson’s gold pressure scale. The Clapeyron slope, dP/dT, determined in this study is consistent with that for the transition boundary between the ilmenite and the perovskite structure in MgSiO₃.  相似文献   

Intrinsic properties of carbon stars. I. Effective temperature scale of N-type carbon stars     

Takashi Tsuji 《Journal of Astrophysics and Astronomy》1981,2(2):213

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Influence of the east-west component of the interplanetary magnetic field on the intensity of the auroral electrojet     

Kazuyuki Hakamada  Takao Aoki  Takashi Murayama 《Planetary and Space Science》1980,28(1):29-39

Analysis of interplanetary data has been made to evaluate the influence of the Biny component of the IMF on the magnitude of the AL index, especially with reference to the contribution of B_y in the reconnection process between the IMF and geomagnetic fields in the dayside part of the magnetosphere. The results of the analysis showed that the effect of Biny on AL is predominantly of a different type from that expected by the current theory of reconnection, and the B_y effect of the latter type was found to be much less significant in magnitude than the theory predicts. The discrepancy may be resolved if the region where the reconnection takes place has an elongated shape.  相似文献   

Magnetic field and current sheets in the corona above active regions     

Takashi Sakurai  Yutaka Uchida 《Solar physics》1977,52(2):397-416

A new method for the calculation of coronal magnetic field is proposed and it is shown to reproduce the EUV features in the corona as observed by Skylab experiments satisfactorily well. One of the remarkable points is that it reproduces the loopy threads in the active region corona and also the large scale field lines connecting active regions. The existence of coronal current is expected wherever the present coronal-current-free model fails to represent the feature. A method of calculating the coronal sheet-current is also developed with the purpose of knowing the shape of the current sheet and the amount of magnetic stress energy stored due the the presence of it by comparing the calculated field configuration with the observed local distortion of the EUV threads. This may be used in pinning down the possible site of the flare and in discussing the flare occurrence in terms of the energy stored there.During the preparation of this work, Poletto et al. (1975) calculated the magnetic field shape in Schmidt's method to compare with the soft X-ray feature obtained by Skylab.  相似文献   

Concentrations of trace elements in marine fish and its risk assessment in Malaysia   总被引：1，自引：0，他引：1  

Agusa T  Kunito T  Yasunaga G  Iwata H  Subramanian A  Ismail A  Tanabe S 《Marine pollution bulletin》2005,51(8-12):896-911

Concentrations of trace elements (V, Cr, Mn, Co, Cu, Zn, Ga, Se, Rb, Sr, Mo, Ag, Cd, Sn, Sb, Cs, Ba, Hg, Tl, Pb and Bi) were determined in muscle and liver of 12 species of marine fish collected from coastal areas in Malaysia. Levels of V, Cr, Mn, Co, Cu, Zn, Ga, Sr, Mo, Ag, Cd, Sn, Ba and Pb in liver were higher than those in muscle, whereas Rb and Cs concentrations showed the opposite trend. Positive correlations between concentrations in liver and muscle were observed for all the trace elements except Cu and Sn. Copper, Zn, Se, Ag, Cd, Cs and Hg concentrations in bigeye scads from the east coast of the Peninsular Malaysia were higher than those from the west, whereas V showed the opposite trend. The high concentration of V in the west coast might indicate oil contamination in the Strait of Malacca. To evaluate the health risk to Malaysian population through consumption of fish, intake rates of trace elements were estimated on the basis of the concentrations of trace elements in muscle of fish and daily fish consumption. Some specimens of the marine fish had Hg levels higher than the guideline value by US Environmental Protection Agency (EPA), indicating that consumption of these fish at the present rate may be hazardous to Malaysian people. To our knowledge, this is the first study on multielemental accumulation in marine fish from the Malaysian coast.  相似文献   

New Boundary Integral Equation Representation for Finite Energy Force-Free Magnetic Fields in Open Space above the Sun   总被引：4，自引：0，他引：4  

Yan  Yihua  Sakurai  Takashi 《Solar physics》2000,195(1):89-109

A boundary integral equation to describe a force-free magnetic field with finite energy content in the open space above the solar surface is found. This is a new representation for a 3-D nonlinear force-free field in terms of the boundary field and its normal gradient at the boundary. Therefore the magnetic field observed on the solar surface can be incorporated into the formulation directly and a standard numerical technique, the boundary element method, can be applied to solve the field. A numerical test case demonstrates the power of the method by recovering the analytical solution to the desired accuracy and its application to practical solar magnetic field problems is straightforward and promising.  相似文献   

Bio-Optical Relationship of Case I Waters: The Difference between the Low- and Mid-Latitude Waters and the Southern Ocean     

Toru Hirawake  Hiroo Satoh  Takashi Ishimaru  Yukuya Yamaguchi  Motoaki Kishino 《Journal of Oceanography》2000,56(3):245-260

Both historic and currently operational chlorophyll algorithms of the satellite-borne ocean color sensors, such as SeaWiFS, were evaluated for in situ spectral radiation and chlorophyll data in some Case I waters, including the waters in the Indian Ocean sector of the Southern Ocean. Chlorophyll a concentration of the data set (n = 73) ranged from 0.04 to 1.01 mg m^–3. The algorithms had higher accuracy for the low- and mid-latitude waters (RMSE: 0.163–0.253), specifically the most recently developed algorithms of OCTS and Sea WiFS showed 0.163 and 0.170 of Root Mean Square Errors, respectively. However, these algorithms had large errors (0.422–0.621) for the Southern Ocean data set and underestimated the surface chlorophyll by more than a factor of 2.6. The absorption coefficients in the blue spectral region retrieved from remote sensing reflectance varied in a nonlinear manner with chlorophyll a concentration, and the value in the Southern Ocean was significantly lower than that in the low- and mid-latitude waters for each chlorophyll a concentration. The underestimation of chlorophyll a concentration in the Southern Ocean with these algorithms was caused by the lower specific absorption coefficient in the region compared with the low- and mid-latitude waters under the same chlorophyll a concentration.  相似文献   

Downslope soil detachment–transport on steep slopes via rain splash     

Afshin Ghahramani  Yoshiharu Ishikawa  Takashi Gomi  Shusuke Miyata 《水文研究》2011,25(15):2471-2480

This study developed a one‐dimensional model of downslope rain splash transport based on field experiments and previous studies. The developed model considers soil detachment processes, ground cover, probability densities, and the effect of overland run‐off in preventing detachment. Field monitoring was conducted to observe precipitation run‐off, ground cover, and sediment production on steep hillslopes. Field‐observed data were used to develop the splash detachment rate equation, probability densities for splash transport, and the maximum splash transport distance. Observed and estimated splash transport showed overall agreement, with some differences for small storm events or events with relatively low intensity, probably caused by variation of overland run‐off depth and connectivity as well as differences in soil surface cohesion at various degrees of wetness. Our model can provide insights on the interactions among rainfall intensity, soil surface condition, soil wetness, and splash transport on forested hillslopes. Copyright © 2011 John Wiley & Sons, Ltd.  相似文献