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1.
如何从脑活动数据中发现具有生物学意义的知识及规律,正成为当今神经信息学理论与实践研究的热点与难点.基于脑电的情绪识别和情绪及其脑机制的关联研究已经成为神经工程和生物医学工程领域的热门课题.本研究基于脑电信号评价情绪状态,尝试借助脑电耳机来监测"毫无头绪"的脑电波,重点开展了听觉激励对改善焦虑情绪状态的实验研究.借助特定中国古风纯音乐产生听觉信号激励,激发出被试者平静放松的情绪状态,从而改善焦虑,发现音乐和情绪之间可能存在的关系.将来在BCI技术研究的基础之上,情绪识别可以进一步满足患有特定疾病（ALS症、脑瘫、脑干中风、脊髓损伤等）的患者人群的某些更高级的需求,即通过脑电分析出其对事物的喜好度,比如音乐的选择,从而设计出更加友善和智能的BCI系统,在医疗康复领域具有很好的应用前景. 相似文献
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人体高发疾病的病理性矿物研究进展 总被引：3，自引：0，他引：3
人体很多疾病病灶中都有矿物晶体沉淀,这些矿物与通过地球化学作用生成的矿物在成分、结构和产状上有很大差异。病理性矿物的矿化过程必然有人体有机组织和成分的参与,并影响着疾病的发生和发展。因此含有丰富的能反映人体环境及周围环境变化影响人体的信息,这些信息具体蕴藏在矿物外部微形貌、内部微结构、化学组成和成因、产状等方面。本文总结了一些高发疾病如肿瘤、心血管疾病、关节炎、中枢神经系统疾病中病理性矿物的分布和特征,综述了矿物与疾病关系的部分研究成果。 相似文献
3.
Pituitary gland, or pituitary for short, is characteristic of all vertebrates. As a “master gland” controlling a multitude of important functions in the body, its evolutionary origin has been an object of investigations of evolutionary biology for two centuries. Previous morphological, ultrastructural and immunohistochemical studies suggested the homology of the Hatschek’s pit of amphioxus and vertebrate pituitary. Developmental genetics study showed that the development of Hatschek’s pit and vertebrate pituitary is both subject to regulation by the common genes such as Pit1, Lhx3 and BMP3b. Our recent studies demonstrated that the Hatschek’s pit is able to secrete growth hormone (GH)-like hormone and thyroid-stimulating hormone (TSH)-like hormone that both play functions similar to vertebrate GH and TSH. We thus think that the emergence of Hatschek’s pit represents one of important events during endocrine network evolution, which laid a foundation for the subsequent formation of a hypothalamic-pituitary system in vertebrates. 相似文献
4.
以太平洋鳕鱼为原料,从鳕鱼脑中分离硫苷脂,确立了提取及纯化的条件,并对硫苷脂的纯度和分子种进行分析。首先,采用氯仿/甲醇(2∶1,v/v)提取总脂。然后,依次采用氯仿/甲醇/水(7∶3∶0.3,v/v/v)洗脱硅胶柱层析,含0.2mol/L乙酸铵的氯仿/甲醇/水(30∶60∶8,v/v/v)洗脱DEAE Sephadex-A25离子交换柱层析,40%甲醇脱盐和100%甲醇洗脱反相C8柱层析,获得硫苷脂纯品。最后,利用500YMC Diol液相色谱柱(3.0mm×250mm,5μm)分离,以正己烷/异丙醇(70∶30,v/v),异丙醇/水/甲酸/氨水(100∶13∶1∶0.14,v/v/v/v)为流动相梯度洗脱,采用负电喷雾电离(ESI)和母离子扫描模式,用液相色谱-串联质谱(LC-MS/MS)法分析了鳕鱼脑硫苷脂的纯度和分子种组成,并比较了其与哺乳动物脑中硫苷脂分子种组成的异同。结果表明,本实验制得的鳕鱼脑硫苷脂纯度为90.74%,与哺乳动物类似,鳕鱼脑硫苷脂的长链碱基以鞘氨醇为主,主要分子种为d18∶1-C24∶1,但脂肪酸的羟基化程度略低,且含少量独特的分子种,如d18∶1-22∶1和d18∶2-25∶2。 相似文献
5.
中国当代地理教授、研究员地域分异 总被引：4，自引：0，他引：4
针对人才地理学对具有特殊专业或学科背景人才研究明显缺失的问题,选取具有地理学背景的教授、研究员为研究对象,对中国当代地理教授、研究员时空格局进行分析,揭示影响其数量、年龄结构及分布特征的因素。结果表明：当代地理教授、研究员地域分布不均衡,南方多于北方,沿海多于内陆。东部多于中部,西部最少。青年地理教授、研究员本区比例则呈现东部少于中部,中部少于西部的特征。工作地区域聚集和空间分异现象明显。其特点反映了中国当代地理教授、研究员地域分异,除受经济地理环境、政治、文化等一系列因素影响外,还有其自身形成原因。 相似文献
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三价砷和五价砷对鱼类乙酰胆碱脂酶的体外抑制比较 总被引：1，自引：0，他引：1
为开展水产品中三价砷的酶法快速检测工作,文中研究了三价砷(As3 + )、五价砷(As5+ )对8种鱼脑中乙酰胆碱酯酶(AChE)的抑制率。结果发现,在10 -7～10 -4mol/L范围内,草鱼和鲫鱼脑中AChE的抑制率与三价砷的浓度负对数值有较好的线性关系,相关系数都在0 .97以上;在10 -6～10 -4mol/L范围内,黑、马鲛、鲈鱼脑中AChE的抑制率与三价砷的浓度负对数值的线性相关系数大于0 .99。对于三价砷,由IC50 得到AChE的敏感性为:美国红鱼>草鱼,鲫,鲈鱼>黑,马鲛>鲤,白鲢。鱼种不同,AChE受到的三价砷、五价砷的抑制作用也不同。在浓度为10 -6～10 -4mol/L范围内,三价砷、五价砷对8种鱼脑中AChE的抑制作用存在极显著差异(p <0 .0 1) ,三价砷对AChE的抑制作用远大于五价砷的抑制作用。 相似文献
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Neuropeptide Y(NPY) is a 36-amino acid peptide of the neuropeptide Y family that plays key roles in the regulation of food intake. In this study,we focused on NPY m RNA expression changes around feeding time and during food deprivation in olive flounder. The olive flounder NPY m RNA levels were analyzed in different tissues and a high level of expression was detected in the brain. We also demonstrated a correlation between NPY expression levels in the brain and feeding schedule. NPY expression levels in olive flounder maintained on a daily scheduled feeding regimen increased shortly before feeding and decreased after the scheduled feeding time. Compared with the-1 h group before feeding,NPY expression in the 3 h group after feeding decreased significantly( P <0.05). Food deprivation led to an 81.7% decrease in NPY m RNA levels in the 24 h fasted group(P <0.05) and a 91.7% decrease in the 48 h fasted group(P <0.05). Therefore,our study demonstrates that NPY expression is associated with food intake in olive flounder. This result reveals the function of NPY in regulating food intake and its potential importance in olive flounder aquaculture. 相似文献
8.
阐述了脑电生理信号检测中,注重低噪声电路设计的同时,特别注重放大器的工艺设计,及应用微机对脑电信号功率谱分析、插值、脑电地形图绘制等系统研制的技术路线和方法。 相似文献
9.
目的 探讨头颅CT增强造影扫描技术在临床应用价值。材料与方法 着重分析48例病例在CT造影增强扫描后的影像表现。结果 病灶均匀一致性强化8袋子例，环状强化9例，点状强化7例，结节状强化12例，不规则强化7例，强化不明显5例，脑膜或小脑幕强化结构清晰38例。结论 头颅CT增强造影扫描能够提高病变的密度分辨力，有利于明确病变的定位和定性，为临床提供更多的重要信息。 相似文献
10.
Are American Interlocking Directorates Associated with Brain Circulation and do They Translate into Higher Corporate Performance? 
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下载免费PDF全文 Sean O'Hagan 《Geographical review》2015,105(3):344-359
This study explores interlocking directorates, with specific focus on those connections when a director sits as an inside director for an American corporation and an outside director for firm located outside of North America. The goal of this study is to explore the spatial relationship between the personal histories of directors and the headquarter's location of the corporate boards on which they sit. First, it was found that a geographical relationship in the interlocking network of American companies exists. Second, it was determined that domestic personal histories played a significant role as 96.5 percent of directors attended a university in the United States and 93.4 percent directors were born there. When North American universities and North American births were deleted from the sample, a geographical pattern also emerges for Asian firms. Finally, the study found that the lone region that consistently displayed greater firm performance where a director's personal history and the interlocked company were the same as Asia. 相似文献