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1.
目的 评价甲强龙联合右美托咪定对体外循环（CPB）心脏瓣膜置换术患者脑认知功能的保护作用。方法 选择内蒙古医科大学附属医院CPB下行心脏瓣膜置换术患者60例,完全随机化分为4组（n=15）,分别为对照组（A组）、甲强龙组（M组）、右美托咪定组（D组）和甲强龙联合右美托咪定组（B组）,在麻醉诱导后气管插管,机械通气。M组在体外循环预冲液加入甲强龙20mg/kg,D组麻醉在诱导后静脉泵注右美托咪定1μg/kg负荷量,之后以0.05μg/（kg·h）速率静脉泵注至术毕,B组既麻醉诱导后静脉注射右美托咪定1μg/kg负荷量,然后以0.05μg/（kg·h）速率静脉输注至术毕又在体外循环预冲液加入甲强龙20mg/kg,A组给于等容量生理盐水。在麻醉后手术前（T1）、CPB即刻（T2）、CPB30min（T3）、CPB结束10min（T4）、术毕（T5）、CPB结束后6h（T6）时采集颈内静脉球部血样,使用酶联免疫吸附实验（ELISA）法测定血清IL-6、IL-10、S100β蛋白和神经元特异性烯醇化酶（NSE）的浓度。记录术前1天术后2天、3天、7天采用简化智能评分量表（MMSE）评估患者认知功能。结果 M组、D组和B组在T1~6各个时间点IL-6、S100β蛋白和NSE均比对照组明显降低,IL-10均比对照组升高,差异有统计学差异（P<0.05）。B组在T1~6各个时间点IL-6、S100β蛋白和NSE均比其他组更低,IL-10均比其他组更高,差异有统计学意义（P<0.05）。M组、D组和B组术后发生认知功能障碍的发生率均高于对照组,B组发生认知功能障碍的发生率最低,差异有统计学意义（P<0.05）。结论 甲强龙和右美托嘧啶均可以有效降低体外循环中IL-6、S100β蛋白和NSE的浓度,降低脑损伤,减少术后认知功能障碍的发生率,联合应用甲强龙和右美托嘧啶对体外循环后脑损伤的保护效果更佳。 相似文献
2.
目的 探讨阿霉素性心肌病大鼠发生心律失常的发病机制。方法 健康wistar雄性大鼠20只,体重200g,适应周围环境1周后,随机将20只wistar雄性大鼠分为对照组（n=10）和阿霉素（ADR）组（n=10）。ADR组的大鼠在1周内进行3次腹腔注射ADR 2mg/kg;同时对照组则进行3次腹腔注射0.9%NaCl （2ml/kg）,停药后让两组大鼠自由饮食4周。7周后对两组大鼠行心脏彩超检测,左心室舒张末径（LVEDd）与左心室收缩末期内径（LVESd）及左心室射血分数（LVEF）,行VG染色观察各组大鼠心肌纤维化情况;扫描电镜染色观察左心室心肌细胞闰盘病理学变化;两组大鼠心肌结缔组织生长因子（CTGF）、转化生长因子β1（TGF-β1）、N型钙黏蛋白（N-cad）、桥粒芯糖蛋白（DSG2）表达应用ELISA法检测;采用Western blot法检测两组大鼠的心肌细胞Cx40 、Cx43、p-Cx43蛋白表达。结果 与对照组相比,阿霉素组大鼠明显出现心室重构,并易出现心律失常;电镜下观察ADR组大鼠心肌细胞闰盘破损严重,间隙增宽,VG染色显示ADR组大鼠病理积分明显高于对照组（P<0.05）;ADR组大鼠相较于对照组大鼠心室肌中CTGF、TGF-β1的表达升高显著,N-cad、DSG2、Cx40、Cx43及p-Cx43的表达明显减低（P<0.05）。结论 ADR组大鼠可能由于心室肌细胞纤维化、闰盘结构受损、缝隙连接重构等原因导致心律失常。 相似文献
3.
目的 探讨研究同型半胱氨酸（homocysteine,Hcy）水平与脑梗死患者亚甲基四氢叶酸还原酶（MTHFR）基因C677T的多态性之间的相关性。方法 选择2012年2月~2015年8月期间在笔者医院住院就诊的450例脑梗死患者作为研究组,其中糖尿病患者181例,非糖尿病患者269例,另外选择285例笔者医院门诊部健康的体检人员作为对照组,分别采用焦磷酸测序的方法检测分析MTHFR基因C677T的多态性,并分析各基因型与Hcy水平之间的相关性。结果 脑梗死组与健康对照组的MTHFR基因型分布之间的差异具有统计学意义（P<0.05）,脑梗死组T基因的频率明显比对照组高,差异有统计学意义（χ2=13.67,P=0.00）。脑梗死组患者的Hcy浓度明显高于健康对照组,差异有统计学意义（t=12.71,P=0.00）。脑梗死组患者各MTHFR基因型患者的Hcy水平之间比较,差异有统计学意义（F=17.68,P=0.00）。非糖尿病脑梗死患者的Hcy水平明显高于糖尿病脑梗死患者,差异有统计学意义（t=2.97,P=0.00）,非糖尿病组TT型的Hcy浓度明显高于糖尿病组,CC型的Hcy浓度明显低于糖尿病组,差异均有统计学意义（t=5.67,2.18;P=0.00,0.03）。糖尿病性脑梗死患者和非糖尿病脑梗死患者中,MTHFR基因为TT型的Hcy水平明显高于CC型和CT型,差异均有统计学意义（P<0.05）,而CC型和CT型的Hcy水平之间比较差异无统计学意义（P>0.05）。结论 脑梗死患者比健康人的MTHFR基因C677T的T等位基因频率高,且脑梗死患者的MTHFR基因C677T为TT基因型时血清中Hcy的水平更高,由此判断TT基因型可能是脑梗死发生的危险因素。 相似文献
4.
目的 通过研究烟草烟雾暴露对哮喘大鼠气道组蛋白去乙酰化酶（histone deacetylase,HDAC）2以及血浆、支气管肺泡灌洗液（BALF）中干扰素（interferon,IFN）-γ、白细胞介素（interleukin,IL）-4表达的影响,探讨HDAC2在辅助性T淋巴细胞（T helper cell）Th1/Th2平衡中的作用。方法 50只雄性Wistar大鼠随机分为对照组、哮喘组、烟雾暴露+哮喘组、布地奈德+哮喘组、布地奈德+烟雾暴露+哮喘组,建立哮喘大鼠模型、哮喘大鼠烟雾暴露模型以及布地奈德干预模型。免疫组织化学法检测各组大鼠气道HDAC2蛋白的表达,酶联免疫吸附试验法（ELISA）检测血浆和BALF中Th1型特征性细胞因子IFN-γ以及Th2型特征性细胞因子IL-4水平。结果 与对照组相比,烟雾暴露+哮喘组、哮喘组大鼠气道HDAC2蛋白表达降低,与哮喘组相比,烟雾暴露+哮喘组大鼠气道HDAC2蛋白表达降低,差异均有统计学意义（P均<0.05）。与布地奈德+哮喘组相比,布地奈德+烟雾暴露+哮喘组大鼠气道HDAC2蛋白表达降低,差异有统计学意义（P<0.05）;与对照组相比,哮喘组大鼠和烟雾暴露+哮喘组大鼠血浆、BALF中IFN-γ表达减少,IL-4表达增加,差异均有统计学意义（P均<0.01）;与哮喘组相比,烟雾暴露+哮喘组大鼠血浆、BALF中IFN-γ表达减少,IL-4表达增加,差异均有统计学意义（P均<0.01）;与布地奈德+哮喘组相比,布地奈德+烟雾暴露+哮喘组大鼠血浆、BALF中IFN-γ表达减少,IL-4表达增加,差异均有统计学意义（P均<0.01）;肺组织HDAC2蛋白的表达与血浆中IFN-γ表达呈正相关（r=0.533,P<0.01）,与IL-4表达呈负相关（r=-0.642,P<0.01）。结论 烟草烟雾暴露可以下调哮喘大鼠模型肺组织HDAC2蛋白的表达,从而影响气道炎症,IFN-γ、IL-4的表达以及布地奈德的治疗效果,这可能是烟草烟雾恶化哮喘气道Th 1/Th2平衡的一个免疫学机制。 相似文献
5.
目的 探讨高脂饮食大鼠肾脏3-羟基-3甲基戊二酰辅酶A合成酶2（HMGCS2）表达及可能调控机制。方法 断乳Wistar 雄性大鼠27只分为3组：正常对照组（CON）、高脂组（HFG）、绿茶多酚（green tea polyphenols,GTPs）组（G）。CON组大鼠喂养普通饲料,HFG组及GTPs组给予高脂饲料,GTPs组同时自由摄食绿茶多酚浓度为1.6g/L水溶液。26周后测定空腹血糖（FPG）、血清胆固醇（TC）、甘油三酯（TG）、低密度脂蛋白（LDL）、高密度脂蛋白（HDL）。免疫印迹法测定肾脏HMGCS2和Sirt3蛋白表达水平。结果 与CON组比较,HFG组大鼠体重和脂肪系数升高,血清FPG、TC、TG、LDL-C/HDLC均升高,差异有统计学意义（P<0.05）;与HFG组比较,GTPs降低大鼠体重和脂肪系数,差异有统计学意义（P<0.05）,GTPs组血清FPG、TC、TG、LDL-C/HDLC均不同程度降低,差异有统计学意义（P<0.05）。与CON组比较,肾脏组织HMGCS2的表达降低,差异有统计学意义（P<0.05）;与HFG组比较,GTPs组增加肾脏HMGCS2的表达,差异有统计学意义（P<0.05）。高脂饮食、正常饮食和GTPs干预后,大鼠肾脏组织Sirt3蛋白表达差异无统计学意义。结论 高脂饮食可降低肾脏组织HMGCS2表达,绿茶多酚可逆转此效应;高脂饮食及绿茶多酚对肾脏组织HMGCS2表达的调控不经Sirt3途径。 相似文献
6.
目的 探讨平均血小板体积等参数在急性胰腺炎病程中变化的临床意义及其对治疗效果评估的价值。方法 回顾性分析53例轻症急性胰腺炎（MAP）患者、25例重症急性胰腺炎（SAP）患者和40例健康者（对照组）的临床资料,检测平均血小板体积（MPV）、血小板计数（PLT）、血小板分布宽度（PDW）、白细胞计数（WBC）、C反应蛋白（CRP）及血清钙离子浓度（Ca2+）等指标。比较并分析上述指标在急性胰腺炎病程中及治疗前后的变化。结果 与对照组比较,急性胰腺炎患者入院时MPV显著升高,差异具有统计学意义（P<0.05）;与MAP组比较,SAP组入院时MPV明显升高,差异具有统计学意义（P<0.05）;SAP组中,MPV在入院后第3天较入院时进一步升高,至入院第5天、第7天逐渐下降;SAP组中,MPV在病程中各时间点与MAP组比较均显著升高,差异有统计学意义（P<0.05）;与治疗前比较,急性胰腺炎患者治疗后MPV显著降低,差异有统计学意义（P<0.05）。结论 急性胰腺炎患者平均血小板体积与病情严重程度及治疗效果相关。 相似文献
7.
We studied pot cultivated Haloxylon ammodendron’s growth, physiological changes and drought resistance under NaCl, H2SiO3,
and NaCl+H2SiO3 treatments. Results show that 0.3 g/kg NaCl, 0.2 g/kg H2SiO3 or 0.3 g/kg NaCl+0.1 g/kg H2SiO3 treatments can
effectively promote growth and improve the drought resistance of H. ammodendron. Compared with that without NaCl treatment,
H. ammodendron’s height, crown diameter and fresh weight increased by 42%, 91% and 62% respectively under 0.3 g/kg NaCl
treatment, and its main stem diameter, main root diameter and main root length increased by 40%, 39% and 23%, respectively.
Compared with that without H2SiO3 treatments, H. ammodendron’s height, crown diameter and fresh weight increased by 36%,
45% and 27% respectively under 0.2 g/kg H2SiO3 treatment, and its main stem diameter, main root diameter and main root length
increased by 23%, 23% and 20%, respectively. Compared with that under 0.3 g/kg NaCl treatment, H. ammodendron’s height,
crown diameter and fresh weight and main root length increased by 9%, 10%, 17% and 12% respectively under 0.3 g/kg
NaCl+0.1 g/kg H2SiO3 treatment. Compared with that under 0.1 g/kg H2SiO3 treatment, H. ammodendron’s height, crown diameter
and fresh weight increased by 28%, 76% and 68% respectively under 0.3 g/kg NaCl+0.1 g/kg H2SiO3 treatment, and its main
stem diameter, main root diameter and main root length increased by 30%, 32% and 27%, respectively. This suggests that moderate
levels of NaCl+H2SiO3 interaction can effectively promote growth and improve drought resistance of H. ammodendron than
separate applications of NaCl or H2SiO3. 相似文献
8.
目的 探讨铁过载对原代培养脐静脉内皮细胞（HUVECS）超氧化物歧化酶（SOD）、活性氧表达的影响及川芎嗪的干预效应。方法 使用酶联免疫法（ELISA）检测体外培养铁过载脐静脉内皮细胞表达的超氧化物歧化酶和活性氧的含量。结果 与空白组比较,模型组超氧化物歧化酶的含量显著降低（P<0.01）,给药组超氧化物歧化酶与模型组比较,差异有统计学意义（P<0.05）;模型组活性氧含量显著高于空白组（P<0.01）,与模型组相比,给药组活性氧含量有明显降低（P<0.05）。结论 川芎嗪能抑制脐静脉内皮细胞铁过载导致的氧化应激,有通过抗氧化应激发挥抗动脉粥样硬化的作用。 相似文献
9.
目的 探讨2型糖尿病（T2DM）、非酒精性脂肪肝（NAFLD）与血清胆碱酯酶（S-CHE）的关系。方法 随机选取221例T2DM患者,将患者分为T2DM合并NAFLD、未合并NAFLD两组。并随机选取同一时期体检的工人及退休人员206例,分为单纯NAFLD和正常对照组。所有被检者进行餐前和餐后2h血糖、糖化血红蛋白（HbA1c）、肝肾功能、血脂、S-CHE的检测以及肝胆胰脾B超检查;对T2DM患者进行空腹C肽和餐后C肽的测定,并计算胰岛素抵抗指数（HOMA2-IR）、胰岛素敏感度指数（HOMA2-%S）、胰岛β细胞功能（HOMA2-%B）。结果 DM合并NAFLD和单纯NAFLD组的S-CHE水平明显高于T2DM未合并NAFLD组和正常对照组（P均<0.01）;随着T2DM病程的延长,S-CHE、ALT、GGT、TG、TC、空腹C肽、餐后C肽的水平逐渐下降,年龄逐渐增高（P<0.05或P<0.01）;将T2DM患者分为A（S-CHE<8900IU/L）、B（S-CHE≥8900IU/L）两组,B组患者的BMI、脂肪肝百分比、ALT、AST、GGT、TG、TC、LDL-C、HOMA2-IR高于A组,HOMA2-%S低于A组（P<0.05或P<0.01）;Pearson偏相关分析显示,校正年龄、性别、病程、HbA1c、FBG、收缩压、舒张压后,S-CHE与HOMA2-IR、BMI、TG、TC、LDL-C、ALT、GGT水平呈正相关,与HOMA2-%S呈负相关（P<0.05或P<0.01）;多元线性回归分析显示,S-CHE与TC、HOMA2-IR、ALT水平呈正相关（R2=0.281,P均<0.01）。结论 S-CHE的水平在NAFLD患者明显增高,而未合并NAFLD的T2DM患者S-CHE的水平并无增高,S-CHE水平升高主要与脂肪肝、胰岛素抵抗及血脂紊乱相关,常规检测S-CHE可以反映T2DM患者胰岛素抵抗的情况以及早期预测NAFLD的发生。 相似文献
10.
目的 探究持续封闭负压引流技术（VSD）对瘢痕切除创面成纤维细胞生长环境的影响。方法 回顾性分析2014年1月~2015年11月于笔者医院行植皮手术的四肢瘢痕切除术后患者60例,根据植皮手术前是否接受VSD治疗分为负压组（n=30）和包扎组（n=30）,负压组均于一期植皮前接受VSD治疗,包扎组未接受VSD治疗。回顾性分析对比两组患者并发症发生率、首次植皮存活率、创面感染率、住院时间之间的差异。并用TUNEL染色、CD34染色法对比瘢痕标本中成纤维细胞凋亡指数及血管生成情况。结果 负压组菌培养阳性率明显低于包扎组（P<0.05）,植皮存活率明显高于包扎组（P<0.05）。两组并发症发生率、住院时间、疼痛评分、随访VSS评分间比较,负压组均明显较低（P<0.05）。负压组成纤维细胞凋亡指数明显较低,微血管计数明显较高（P<0.05）。结论 负压封闭引流可以减轻瘢痕切除创面感染率,有效减轻炎性水肿,且可以通过改变局部血液循环微环境以及机械应力作用促进成纤维细胞增殖分裂,提高创面恢复效果。 相似文献
11.
《The Journal of geography》2012,111(6):290-300
Abstract Ralph and Mollie Izzard. A Walk in the Mountains, A Family's Trip Through the High Lebanon. Wesley Calef. Private Grazing and Public Lands, Studies of the Local Management of the Taylor Grazing Act. S. H. Steinberg (editor). The Statesman's Yearbook, 1960-1961. E. Joseph Dreany. Alaska. John C. and Elsie F. Caldwell. Our Neighbors in Japan. R. J. Harrison Church. West Africa: A Study of the Environment and of Man's Use of it. Alex Somme, editor. A Geography of Norden. 相似文献
12.
13.
《The Journal of geography》2012,111(5):238-243
Abstract The World Book Encyclopedia of People and Places.Chicago: World Book Inc. 1992. $174.00 (school price: $149.00). The Spanish-American Homeland: Four Centuries in New Mexico's Rio ArribaBaltimore and London: 1992. The Johns Hopkins University Press. 294 pp. $39.95, cloth. ISBN 0-8018-3990-4. Place, Modernity, and the Consumer's WorldBaltimore: The Johns Hopkins University Press. 1992. 35 illustrations, endnotes, author index, subject index, ISBN 0-8018-4336-7. Environmental Hazards in the Valley of MexicoLincoln, Nebraska: National Council for Geographic Education, Great Plains National. 60 slides, annotations, bibliography, $70.00. Asian Americans: An Interpretive HistoryBoston: Twayne Publisher. 1991. xv and 242 pp., Maps, photos, chronology, bibliography, index. ISBN 0-8057-84373. $1 1.95, paperback. Latin America and the Caribbean: A Systematic and Regional Survey 相似文献
14.
《The Journal of geography》2012,111(9):391-400
Abstract 1960 Report on Jamaica. British Information Services, 845 Third Ave., New York 22, N.Y., 1963. iv and 477 pages with table of contents, photographs, graphs and bibliography. $3.50. George W. Hoffman. The Balkans in Transition. D. Van Nostrand Co., Princeton, N.J., 1963. 124 pages. $1.45. Stephen W. Sears and Marvin W. McFarland. Air War Against Hitler's Germany. American Heritage Publishing Co., Inc., New York, 1964. 154 pages including index. $3.95. Olive TV. Burt. Wind Before the Dawn. John Day Co., New York, 19G4. 192 pages. $3.50. Los Angeles Geographical Society. Day Tours: Geographical Journeys in the Los Angeles Area. Glenn Cunningham, Editor. Pacific Books, Palo Alto, California, 1964. 277 pages. Maps. $3.95. Editorial note: In answer to inquiries, other Highlighting features on Southeast Asia topics which have appeared in The Journal of Geography are: (1) “Federation of Malaysia,” May, 1963, 230–231, (2) “Indonesian Panism,” May, 1964, 232–233, (3) “Disintegrating Laos,” September, 1964, 284–285, (4) “Splitting Wedge of Communism,” October, 1964, 334–335 and (5) “Cambodia's Three Sea Outlets,” November, 1964, 382–383. John H. Bradley. World Geography. Fourth Edition. Ginn and Co., Boston 17, Mass., 1964. 619 pages with table of contents, list of maps, maps, illustrations, photographs colored and black and white, bibliography, statistics, study guides and index. For high school grades 9–12. $6.20. Atlas of Florida. Compiled by Erwin Raisz and associates; text by John R. Dunkle. University of Florida Press, Gainesville, Fla., 1964. 52 pages with maps, graphs, diagrams, sketches, photographs and fold-in rear cover pocket map. $7.50. Frank R. Brandenburg. The Making of Modern Mexico Prentice-Hall Inc., Englewood Cliffs, N.J., 1964. 379 pages with index $8.95. A. V. Hardy and F. J. Monkhouse. The Physical Landscape in Pictures. Cambridge University Press, American Branch, 32 E. 57th St., New York, 1964. 92 pages with table of contents, preface and 92 black and white photographs. $1.75 paperbound. Mary F. Horkheimer and John W. Diffor (eds.). Educators Guide to Free Films. Educators Progress Service, Randolph, Wis., 1964. 631 pages. $9.00. Marton Pecsi and Bela Sarfalvi. The Geography of Hungary. Collet's, 44–45 Museum St., London, 1964. xii and 299 pages, black and white illustrations and two colored insert maps. About $4.55. Stephen H. Longrigg. The Middle East: A Social Geography. Aldine Publishing Co., Chicago, 1962. 291 pages. $6.95. 相似文献
15.
西江河口段溶解无机碳稳定同位素组成的时空变化 总被引：3，自引：1，他引：2
For researching the spatio-temporal variation of the stable isotopic composition of the riverine dissolved inorganic carbon（DIC）,we had carried out a survey throughout the hydrologic year during which theδ^13CDIC of the surface water and its physicochemical parameter were examined along the Xijiang River Inner Estuarine waterway from September 2006 to June 2007.There was a striking seasonal variation on the averageδ^13CDIC,as the averageδ^13CDIC in summer（-13.91‰）or autumn（-13.09‰）was much less than those in spring（-11.71‰）or winter（-12.26‰）.The riverineδ13C DIC was controlled by decomposed condition of the riverine organic matter linking the seasonal variation of the physicochemical parameter in the surface water according to the correlation analysis which indicated notable relations betweenδ^13CDIC and water temperature（p=0.000;r=-0.569）or betweenδ^13CDIC and oxide-reduction potential（p=0.000;r=0.646）.The striking positive correlation between δ^13CDIC and the sampling distance happened in the summer rainy season,while striking negative correlation happened in the spring dry season,indicating that river-sea interaction influenced water physicochemical parameters and controlled the riverine DIC property in the survey waterway.In view of the riverineδ^13CDIC decreasing for the decomposition of the terrestrial organic matter in the rainy season in summer and increasing for the briny invaded zone extending in the spring dry season along the waterway from the Makou gauging station to the Modaomen outlet,theδ^13CDIC spatio-temporal variation was closely related to the geographical environment of the Xijiang drainage basin. 相似文献
16.
《The Journal of geography》2012,111(3):99-109
17.
《The Journal of geography》2012,111(1):40-45
Abstract Richard Edes Harrison. The Ginn World Atlas. Ginn &; Co., Statler Office Bldg., Boston 17, Mass., 1963. 62 pages (single page 7 1/2 × 10 in.) with table of contents, colored maps and index. $1.00. National Geographic Society. Atlas of the World. National Geographic Society, Washington 6, D.C., 1963. 304 pages, including 115 pages of 11-color maps, with 127,071 place names. With introduction, table of contents, etc. The price for the standard edition in a flexible, leather-grained plastic cover is $18.75. The deluxe edition with hard-backed cover in a matching slipcase and gold-stamped lettering with the owner's name is $24.50. Mary Louise Clifford. The Land and People of Afghanistan. J. B. Lippincott Company, E. Washington Sq., Philadelphia, Pa., 1962. 160 pages, illustrated with photographs, map and index. $3.25. Pradyumna P. Karan and William M. Jenkins, Jr. The Himalayan Kngdoms: Bhutan, Sikkim, and Nepal. D. Van Nostrand Co., Inc., 120 Alexander St., Princeton, N.J., 1963. 144 pages with preface, table of contents, appendix, bibliography and index. Included are maps and sketches. $1.45. Donald B. Cole. Atlas of American History. Ginn and Co., Statler Office Bldg., Boston 17, Mass., 1963. 151 pages with table of contents, maps and index. $1.60. (paperback) D. M. LeBourdais. Stefansson: Ambassador of the North. Harvest House Limited, 220 Elm Ave., Montreal 6, P. Q., Can., 1962. 204 pages with table of contents, map and index. $2.50 (paperback) Elvajean Hall. The Land and People of Norway (Portraits of the Nations Series). J. B, Lippincott Co., E. Washington Sq., Philadelphia 5, Pa., 1963. 158 pages with table of contents, one place name map, photographs and index. $3.25. Sir Alan Burns. Fiji. British Information Services, 845 Third Ave., New York 22, N.Y., 1963. xv and 255 pages with table of contents, illustrations, photographs, drawings, maps, appendices and index. $6.00. George B. Cressey. Asia's Lands and Peoples. McGraw-Hill Book Company, Inc., 330 West 42nd St., New York 36, N.Y., 1963. 652 pages plus table of contents and index. $9.95. S. Carl Hirsch. The Globe for the Space Age. The Viking Press, 625 Madison Ave., New York, N.Y., 1963. 88 pages including table of contents, index, drawings, suggestions for further reading and list of globe manufacturers. $8.75. Cuchlaine A. M. King. An Introduction to Oceanography. McGraw Hill Book Company, Inc., 330 West 42nd Street, New York 36, N.Y., 1963. xii and 337 pages with table of contents, index and illustrations. $7.95. William Bixby. Waves, Pathways of Energy. David McKay &; Co., Inc., 119 W. 40th St., New York 18, N.Y., 1963. 160 pages, illustrations, suggested further readings index. $3.50. Hans H. Lansberg, Leonard L. Fischman and Joseph L. Fisher. Resources in America's Future: Patterns of Requirements and Availabilities 1960–2000. Johns Hopkins Press, Baltimore 18, Md., 1963. 1067 pages with black and white and colored ilustrations, table of contents, appendices and index. $15.00. C. Daryll Forde. Habitat, Economy &; Society. E. P. Dutton &; Co., Inc., 201 Park Avenue South, New York 3, N.Y., 1963. xv and 500 pages with preface, table of contents, illustrations, maps, drawings, chapter references, bibliography and index $2.35. Patricia Horkheimer Suttles. Educators Guide to Free Science Materials, 4th ed. Educators Progress Service, Randolph, Wis., 1963. XV and 313 pages with publisher's foreword, table of contents, general directions, title index, subject index, source and availability index and eleven units. $7.75. Irwin Isenberg (associate editor). The Soviet Satellites of Eastern Europe. Scholastic Book Services, Scholastic Magazines, Inc., New York, N.Y., 1963. 159 pages with photographs and index. Sixty-five cents, (paperback) 相似文献
18.
《Norsk geografisk tidsskrift. Norwegian journal of geography》2012,66(4):253-260
A statistical model for automated mapping of the spatial distribution of permafrost in the area of Corral del Veleta in south-east Spain (3703' N, 322' W; 3398 m a.s.l.) was developed and applied. The model uses a relationship between permafrost occurrence as indicated by BTS measurements, and variables such as altitude, solar radiation and summer snow cover. The model was implemented within a geographical information system (GIS) and determines the spatial distribution of probable permafrost in Corral del Veleta. Validation was achieved by comparing the predicted permafrost distribution with the results of recent fieldwork, such as geomorphic mapping, geophysical soundings and ground temperature logging. 相似文献
19.
目的 研究儿童贵重药片常用剂量,为药片最适包装规格提供参考。方法 根据2013年1月~2016年9月间儿童医院住院患者常用的几种贵重药片各剂量使用情况进行分析,分析现有规格使用率及最高使用率药品剂量,以确定需要生产的儿童药片剂量规格。结果 儿童医院常用的单价 >10元的片剂药品共5种,其中希舒美片剂因有儿童专用的干混悬剂剂型,不列入研究范围。其余4种药品单片价格均 >50元,且斯沃片和威凡片单片价格 >300元。莱立康片和威凡片现有规格剂量可以满足儿科临床需求,而斯沃片和全可利片整理使用率均 <10%,不能满足儿科临床实际需求。需要增加100mg规格的斯沃片和7.8mg规格的全可利片。结论 现有的儿童用贵重片剂不能完全满足儿科临床需求,需要进行适当的剂量调整。 相似文献
20.
Simon Belle Claire Parent Victor Frossard Valérie Verneaux Laurent Millet Panagiota-Myrsini Chronopoulou Pierre Sabatier Michel Magny 《Journal of Paleolimnology》2014,52(3):215-228
Freshwater lakes are important sources of methane (CH4) emissions, by organic matter degradation under anaerobic conditions (methanogenesis). Previous studies suggest that lakes contribute up to 16 % of natural emissions. About 60 % of the CH4 produced is used as an energy source by methane-oxidizing bacteria (MOB—methanotrophs), which could support higher trophic levels, especially Chironomidae (Diptera). Because biogenic methane has a very low stable carbon isotope value, evidence of methane-derived organic-matter assimilation can be tracked by stable carbon isotope analysis in consumers such as chironomids. In some cases, however, chironomid δ13C values are not low enough to unambiguously demonstrate methanotroph assimilation and an alternative line of evidence is required. Analysis of ancient DNA (aDNA) from the methanotroph community preserved in lake sediment provides reliable information about past methane oxidation in freshwater lakes. A combination of these two approaches was used to study a sediment core from the deepest zone of Lake Narlay (Jura, France), which covers the last 1,500 years of sediment accumulation. Results show a significant change ca. AD 1600, with an increase in the proportion of MOB in the total bacteria community, and a decrease in chironomid head-capsule δ13C. These trends suggest assimilation of MOB by chironomid larvae, and account for up to 36 % of the chironomid biomass. The data also provide information about the feeding behavior of chironomids, with evidence for preferential assimilation of methanotroph type I and the NC10 phylum. The combination of aDNA analysis and carbon stable isotopes strengthens the reliability of inferences about carbon sources incorporated into chironomid biomass. 相似文献